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New avenues for anti-epileptic drug discovery and development

Nature reviews. Drug discovery, 2013-10, Vol.12 (10), p.757-776

2013

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Strengthening the Case for Epilepsy Drug Development: Bridging Experiences from the Alzheimer’s Disease Field—An Opinion

Neurochemical research, 2017-07, Vol.42 (7), p.2099-2115

Twyman, Roy E.

2017

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Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap

Nature reviews. Neurology, 2021-04, Vol.17 (4), p.231-242

2021

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Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?

Epilepsia (Copenhagen), 2020-03, Vol.61 (3), p.359-386

2020

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Revision of Unicompartmental Knee Arthroplasty Versus Primary Total Knee Arthroplasty

The Journal of arthroplasty, 2015-04, Vol.30 (4), p.592-594

2015

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Large-conductance calcium-activated potassium channel haploinsufficiency leads to sensory deficits in the visual system: a case report

Journal of medical case reports, 2022-05, Vol.16 (1), p.180-180, Article 180

2022

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Electroretinography and contrast sensitivity, complementary translational biomarkers of sensory deficits in the visual system of individuals with fragile X syndrome

Journal of neurodevelopmental disorders, 2021-12, Vol.13 (1), p.1-45, Article 45

2021

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Validation of revision data for total hip and knee replacements undertaken at a high volume orthopaedic centre against data held on the National Joint Registry

Journal of orthopaedic surgery and research, 2019-10, Vol.14 (1), p.318-318, Article 318

2019

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Antiepileptogenesis and disease modification: Clinical and regulatory issues

Epilepsia open, 2021-09, Vol.6 (3), p.483-492

2021

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Blinded prospective evaluation of computer-based mechanistic schizophrenia disease model for predicting drug response

PloS one, 2012-12, Vol.7 (12), p.e49732-e49732

2012

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Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored antiepileptogenesis and disease modification workshop

Epilepsia open, 2021-06, Vol.6 (2), p.276-296

2021

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Pharmacokinetic interactions of topiramate

Clinical pharmacokinetics, 2004-01, Vol.43 (12), p.763-780

2004

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Can local administration of tranexamic acid during total knee arthroplasty reduce blood loss and transfusion requirements in the absence of surgical drains?

European journal of orthopaedic surgery & traumatology, 2014-04, Vol.24 (3), p.379-384

2014

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The Caenorhabditis elegans unc-49 Locus Encodes Multiple Subunits of a Heteromultimeric GABA Receptor

The Journal of neuroscience, 1999-07, Vol.19 (13), p.5348-5359

1999

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Short-term outcome of unicompartmental knee arthroplasty in the octogenarian population

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2018-05, Vol.26 (5), p.1571-1576

2018

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Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels

Epilepsy & behavior, 2004-12, Vol.5 (6), p.866-872

2004

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Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site

Neuron (Cambridge, Mass.), 1995-04, Vol.14 (4), p.755-762

1995

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Pharmacological characterization of the homomeric and heteromeric UNC‐49 GABA receptors in C. elegans

British journal of pharmacology, 2003-03, Vol.138 (5), p.883-893

2003

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A case report: painful Hoffa’s fat pad herniation

Current orthopaedic practice, 2018-09, Vol.29 (5), p.510-511

2018

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Potent and selective pharmacodynamic synergy between the metabotropic glutamate receptor subtype 2–positive allosteric modulator JNJ‐46356479 and levetiracetam in the mouse 6‐Hz (44‐mA) model

Epilepsia (Copenhagen), 2018-03, Vol.59 (3), p.724-735

2018

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Efficacy of mGlu2‐positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures

Epilepsia (Copenhagen), 2017-03, Vol.58 (3), p.484-493

2017

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p11 and gene therapy for severe psychiatric disorders: a practical goal?

Science translational medicine, 2010-10, Vol.2 (54), p.54ps51

2010

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Removal of screws with damaged heads—A technical tip

Injury extra, 2008-10, Vol.39 (10), p.345-346

2008

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Randomized dose-controlled study of topiramate as first-line therapy in epilepsy

Acta neurologica Scandinavica, 2005-10, Vol.112 (4), p.214-222

2005

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Efficacy of mGlu 2 -positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures

Epilepsia (Copenhagen), 2017-03, Vol.58 (3), p.484-493

2017

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New avenues for anti-epileptic drug discovery and development

Strengthening the Case for Epilepsy Drug Development: Bridging Experiences from the Alzheimer’s Disease Field—An Opinion

Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap

Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?

Revision of Unicompartmental Knee Arthroplasty Versus Primary Total Knee Arthroplasty

Large-conductance calcium-activated potassium channel haploinsufficiency leads to sensory deficits in the visual system: a case report

Electroretinography and contrast sensitivity, complementary translational biomarkers of sensory deficits in the visual system of individuals with fragile X syndrome

Validation of revision data for total hip and knee replacements undertaken at a high volume orthopaedic centre against data held on the National Joint Registry

Antiepileptogenesis and disease modification: Clinical and regulatory issues

Blinded prospective evaluation of computer-based mechanistic schizophrenia disease model for predicting drug response

Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored antiepileptogenesis and disease modification workshop

Pharmacokinetic interactions of topiramate

Can local administration of tranexamic acid during total knee arthroplasty reduce blood loss and transfusion requirements in the absence of surgical drains?

The Caenorhabditis elegans unc-49 Locus Encodes Multiple Subunits of a Heteromultimeric GABA Receptor

Short-term outcome of unicompartmental knee arthroplasty in the octogenarian population

Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels

Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site

Pharmacological characterization of the homomeric and heteromeric UNC‐49 GABA receptors in C. elegans

A case report: painful Hoffa’s fat pad herniation

Potent and selective pharmacodynamic synergy between the metabotropic glutamate receptor subtype 2–positive allosteric modulator JNJ‐46356479 and levetiracetam in the mouse 6‐Hz (44‐mA) model

Efficacy of mGlu2‐positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures

p11 and gene therapy for severe psychiatric disorders: a practical goal?

Removal of screws with damaged heads—A technical tip

Randomized dose-controlled study of topiramate as first-line therapy in epilepsy

Efficacy of mGlu 2 -positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures

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