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Development of a human peripheral blood ex vivo model for rapid protein biomarker detection and applications to radiation biodosimetry

PloS one, 2023-08, Vol.18 (8), p.e0289634-e0289634

2023

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Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

Radiation oncology (London, England), 2019-08, Vol.14 (1), p.150-10, Article 150

2019

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A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays

Scientific reports, 2022-12, Vol.12 (1), p.21077-13, Article 21077

2022

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Interlaboratory comparison of high-throughput protein biomarker assay quantifications for radiation exposure classification

PloS one, 2024-04, Vol.19 (4), p.e0301418

2024

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BAX and DDB2 as biomarkers for acute radiation exposure in the human blood ex vivo and non-human primate models

Scientific reports, 2024-08, Vol.14 (1), p.19345-11

2024

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Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells

PloS one, 2018-01, Vol.13 (1), p.e0191402-e0191402

2018

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Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques

BMC genomics, 2023-03, Vol.24 (1), p.139-139, Article 139

2023

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Machine learning methodology for high throughput personalized neutron dose reconstruction in mixed neutron + photon exposures

Scientific reports, 2021-02, Vol.11 (1), p.4022-4022, Article 4022

2021

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Cannabinoids, the Heart of the Matter

Journal of the American Heart Association, 2018-07, Vol.7 (14)

2018

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Immunological and toxinological responses to jellyfish stings

Inflammation & allergy drug targets, 2011-10, Vol.10 (5), p.438-446

2011

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γ-H2AX Kinetic Profile in Mouse Lymphocytes Exposed to the Internal Emitters Cesium-137 and Strontium-90

PloS one, 2015-11, Vol.10 (11), p.e0143815-e0143815

2015

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In vitro RABiT measurement of dose rate effects on radiation induction of micronuclei in human peripheral blood lymphocytes

Radiation and environmental biophysics, 2016-03, Vol.55 (1), p.53-59

2016

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TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure

Channels (Austin, Tex.), 2019-01, Vol.13 (1), p.1-16

2019

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High-Throughput γ-H2AX Assay Using Imaging Flow Cytometry

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2635, p.123

2023

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Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration

BMC molecular and cell biology, 2019-05, Vol.20 (1), p.13-13, Article 13

2019

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Radiation Biodosimetry: Current Status and Future Initiatives

Cytogenetic and genome research, 2024-03, Vol.163 (3-4), p.85-88

2024

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Comparison of Isolated Lymphocyte and Whole Blood-Based CBMN Assays for Radiation Triage

Cytogenetic and genome research, 2024-03, Vol.163 (3-4), p.110-120

2024

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Biomarkers for Radiation Biodosimetry and Correlation with Hematopoietic Injury in a Humanized Mouse Model

Radiation research, 2024-09, Vol.202 (3)

2024

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Sex and dose rate effects in automated cytogenetics

Radiation protection dosimetry, 2023-09, Vol.199 (14), p.1495-1500

2023

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Automated Triage Radiation Biodosimetry: Integrating Imaging Flow Cytometry with High-Throughput Robotics to Perform the Cytokinesis-Block Micronucleus Assay

Radiation research, 2019-04, Vol.191 (4), p.342

2019

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Prediction of In Vivo Radiation Dose Status in Radiotherapy Patients using Ex Vivo and In Vivo Gene Expression Signatures

Radiation research, 2011-03, Vol.175 (3), p.257-265

2011

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High‐throughput measurement of double strand break global repair phenotype in peripheral blood mononuclear cells after long‐term cryopreservation

Cytometry. Part A, 2023-07, Vol.103 (7), p.575-583

2023

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Cytogenetic Damage of Human Lymphocytes in Humanized Mice Exposed to Neutrons and X Rays 24 h After Exposure

Cytogenetic and genome research, 2021-09, Vol.161 (6-7), p.352-361

2021

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Assessment of Micronuclei Frequency in the Peripheral Blood of Adult and Pediatric Patients Receiving Fractionated Total Body Irradiation

Cytogenetic and genome research, 2024-03, Vol.163 (3-4), p.121-130

2024

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Application of the Cytokinesis-Block Micronucleus Assay for High-Dose Exposures Using Imaging Flow Cytometry

Cytogenetic and genome research, 2024-03, Vol.163 (3-4), p.131-142

2024

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Development of a human peripheral blood ex vivo model for rapid protein biomarker detection and applications to radiation biodosimetry

Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays

Interlaboratory comparison of high-throughput protein biomarker assay quantifications for radiation exposure classification

BAX and DDB2 as biomarkers for acute radiation exposure in the human blood ex vivo and non-human primate models

Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells

Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques

Machine learning methodology for high throughput personalized neutron dose reconstruction in mixed neutron + photon exposures

Cannabinoids, the Heart of the Matter

Immunological and toxinological responses to jellyfish stings

γ-H2AX Kinetic Profile in Mouse Lymphocytes Exposed to the Internal Emitters Cesium-137 and Strontium-90

In vitro RABiT measurement of dose rate effects on radiation induction of micronuclei in human peripheral blood lymphocytes

TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure

High-Throughput γ-H2AX Assay Using Imaging Flow Cytometry

Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration

Radiation Biodosimetry: Current Status and Future Initiatives

Comparison of Isolated Lymphocyte and Whole Blood-Based CBMN Assays for Radiation Triage

Biomarkers for Radiation Biodosimetry and Correlation with Hematopoietic Injury in a Humanized Mouse Model

Sex and dose rate effects in automated cytogenetics

Automated Triage Radiation Biodosimetry: Integrating Imaging Flow Cytometry with High-Throughput Robotics to Perform the Cytokinesis-Block Micronucleus Assay

Prediction of In Vivo Radiation Dose Status in Radiotherapy Patients using Ex Vivo and In Vivo Gene Expression Signatures

High‐throughput measurement of double strand break global repair phenotype in peripheral blood mononuclear cells after long‐term cryopreservation

Cytogenetic Damage of Human Lymphocytes in Humanized Mice Exposed to Neutrons and X Rays 24 h After Exposure

Assessment of Micronuclei Frequency in the Peripheral Blood of Adult and Pediatric Patients Receiving Fractionated Total Body Irradiation

Application of the Cytokinesis-Block Micronucleus Assay for High-Dose Exposures Using Imaging Flow Cytometry

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