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Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3

PloS one, 2012-08, Vol.7 (8), p.e43965-e43965

2012

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Structural Diversity in the RGS Domain and Its Interaction with Heterotrimeric G Protein α-Subunits

Proceedings of the National Academy of Sciences - PNAS, 2008-04, Vol.105 (17), p.6457-6462

2008

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Targeting cancer using fragment based drug discovery

Anti-cancer agents in medicinal chemistry, 2012-01, Vol.12 (1), p.40-48

2012

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Engineering a Selectable Marker for Hyperthermophiles

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11422-11431

2005

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Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

Molecular & cellular proteomics, 2023-08, Vol.22 (8), p.100609-100609, Article 100609

2023

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Preparation and crystallographic characterization of C60Cl24

Chemical communications (Cambridge, England), 2005-01 (11), p.1411-1413

2005

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Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3611-3625

2015

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Correction to “Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta”

Journal of medicinal chemistry, 2023-03, Vol.66 (5), p.3649-3649

2023

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Structural and functional characterization of human Iba proteins

European journal of biochemistry, 2008-09, Vol.275 (18), p.4627-4640

2008

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Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus

Journal of molecular biology, 2007-08, Vol.371 (5), p.1249-1260

2007

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Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)

Bioorganic & medicinal chemistry, 2014-02, Vol.22 (3), p.967-977

2014

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Nonlinear Lensing in an Unpumped Antiresonant Semiconductor Disk Laser Gain Structure

IEEE photonics technology letters, 2016-07, Vol.28 (13), p.1395-1398

2016

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Synthesis and structure-activity relationships for 1-(4-(piperidin-1-ylsulfonyl)phenyl)pyrrolidin-2-ones as novel non-carboxylate inhibitors of the aldo-keto reductase enzyme AKR1C3

European journal of medicinal chemistry, 2013-04, Vol.62, p.738-744

2013

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Automated technologies and novel techniques to accelerate protein crystallography for structural genomics

Proteomics (Weinheim), 2008-02, Vol.8 (4), p.612-625

2008

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Saturated gain spectrum of VECSELs determined by transient measurement of lasing onset

Optics express, 2014-03, Vol.22 (6), p.6919-6924

2014

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3‑(3,4-Dihydroisoquinolin-2(1H)‑ylsulfonyl)benzoic Acids: Highly Potent and Selective Inhibitors of the Type 5 17-β-Hydroxysteroid Dehydrogenase AKR1C3

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7746-7758

2012

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Fragment library design considerations

Wiley interdisciplinary reviews. Computational molecular science, 2012-11, Vol.2 (6), p.868-885

2012

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Structural Insight into Substrate Binding and Catalysis of a Novel 2-Keto-3- deoxy- d-arabinonate Dehydratase Illustrates Common Mechanistic Features of the FAH Superfamily

Journal of molecular biology, 2008-05, Vol.379 (2), p.357-371

2008

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Fragment-based drug discovery and protein-protein interactions

Research and reports in biochemistry, 2014-01, Vol.4, p.13

2014

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A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors

SLAS discovery, 2018-01, Vol.23 (1), p.11-22

2018

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Structural and functional conservation profiles of novel cathepsin L-like proteins identified in the Drosophila melanogaster genome

Journal of biomolecular structure & dynamics, 2013-12, Vol.31 (12), p.1481-1489

2013

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Studying protein-ligand interactions using X-ray crystallography

Methods in molecular biology (Clifton, N.J.), 2013, Vol.1008, p.457

2013

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A role for quaternary structure in the substrate specificity of leucine dehydrogenase

Structure (London), 1995-07, Vol.3 (7), p.693-705

1995

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Determinants of Substrate Specificity in the Superfamily of Amino Acid Dehydrogenases

Biochemistry (Easton), 1997-12, Vol.36 (51), p.16109-16115

1997

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Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3

Structural Diversity in the RGS Domain and Its Interaction with Heterotrimeric G Protein α-Subunits

Targeting cancer using fragment based drug discovery

Engineering a Selectable Marker for Hyperthermophiles

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta

Preparation and crystallographic characterization of C60Cl24

Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3

Correction to “Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta”

Structural and functional characterization of human Iba proteins

Crystal Structure and Biochemical Properties of the d-Arabinose Dehydrogenase from Sulfolobus solfataricus

Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)

Nonlinear Lensing in an Unpumped Antiresonant Semiconductor Disk Laser Gain Structure

Synthesis and structure-activity relationships for 1-(4-(piperidin-1-ylsulfonyl)phenyl)pyrrolidin-2-ones as novel non-carboxylate inhibitors of the aldo-keto reductase enzyme AKR1C3

Automated technologies and novel techniques to accelerate protein crystallography for structural genomics

Saturated gain spectrum of VECSELs determined by transient measurement of lasing onset

3‑(3,4-Dihydroisoquinolin-2(1H)‑ylsulfonyl)benzoic Acids: Highly Potent and Selective Inhibitors of the Type 5 17-β-Hydroxysteroid Dehydrogenase AKR1C3

Fragment library design considerations

Structural Insight into Substrate Binding and Catalysis of a Novel 2-Keto-3- deoxy- d-arabinonate Dehydratase Illustrates Common Mechanistic Features of the FAH Superfamily

Fragment-based drug discovery and protein-protein interactions

A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors

Structural and functional conservation profiles of novel cathepsin L-like proteins identified in the Drosophila melanogaster genome

Studying protein-ligand interactions using X-ray crystallography

A role for quaternary structure in the substrate specificity of leucine dehydrogenase

Determinants of Substrate Specificity in the Superfamily of Amino Acid Dehydrogenases

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