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Pneumolysin: Pathogenesis and Therapeutic Target

Frontiers in microbiology, 2020-07, Vol.11, p.1543-1543

2020

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Streptococcus pneumoniae : Invasion and Inflammation

Microbiology spectrum, 2019-03, Vol.7 (2)

2019

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Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

Nature communications, 2016-02, Vol.7 (1), p.10859-10859, Article 10859

2016

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Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004383-e1004383

2014

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Control of virulence by small RNAs in Streptococcus pneumoniae

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002788-e1002788

2012

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Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children

Frontiers in cellular and infection microbiology, 2020-10, Vol.10, p.585791-585791

Tuomanen, Elaine I

2020

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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Nature immunology, 2008-12, Vol.9 (12), p.1399-1406

2008

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Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis

The Journal of infectious diseases, 2004-11, Vol.190 (9), p.1661-1669

2004

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Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex

mBio, 2023-06, Vol.14 (3), p.e0051023-e0051023

2023

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Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid—CbpA Peptide Recombinant Fusion Protein

The Journal of infectious diseases, 2014-04, Vol.209 (7), p.1116-1125

2014

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Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System

Frontiers in cellular and infection microbiology, 2020-10, Vol.10, p.588378-588378

2020

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Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis

mBio, 2017-01, Vol.8 (1)

2017

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AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness

PloS one, 2016-01, Vol.11 (1), p.e0146785

2016

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Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

The Journal of clinical investigation, 2010-02, Vol.120 (2), p.627-635

2010

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Genomic Analyses of Pneumococci from Children with Sickle Cell Disease Expose Host-Specific Bacterial Adaptations and Deficits in Current Interventions

Cell host & microbe, 2014-05, Vol.15 (5), p.587-599

2014

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Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza

The Journal of infectious diseases, 2011-11, Vol.204 (9), p.1358-1366

2011

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Multi-Valent Protein Hybrid Pneumococcal Vaccines: A Strategy for the Next Generation of Vaccines

Vaccines (Basel), 2021-03, Vol.9 (3), p.209

2021

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Identification of a Candidate Streptococcus pneumoniae Core Genome and Regions of Diversity Correlated with Invasive Pneumococcal Disease

Infection and Immunity, 2006-08, Vol.74 (8), p.4766-4777

2006

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Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster

Nature communications, 2014-11, Vol.5 (1), p.5411-5411, Article 5411

2014

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Microarray Analysis of Pneumococcal Gene Expression during Invasive Disease

Infection and Immunity, 2004-10, Vol.72 (10), p.5582-5596

2004

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Calcium efflux is essential for bacterial survival in the eukaryotic host

Molecular microbiology, 2008-10, Vol.70 (2), p.435-444

2008

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The pneumococcus: epidemiology, microbiology, and pathogenesis

Cold Spring Harbor perspectives in medicine, 2013-07, Vol.3 (7), p.a010215-a010215

2013

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β-Arrestin 1 Participates in Platelet-Activating Factor Receptor-Mediated Endocytosis of Streptococcus pneumoniae

Infection and Immunity, 2005-12, Vol.73 (12), p.7827-7835

2005

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Preinfection Systemic Inflammatory Markers and Risk of Hospitalization Due to Pneumonia

American journal of respiratory and critical care medicine, 2005-12, Vol.172 (11), p.1440-1446

2005

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Host–pathogen interactions in bacterial meningitis

Acta Neuropathologica, 2016-02, Vol.131 (2), p.185-209

2016

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Pneumolysin: Pathogenesis and Therapeutic Target

Streptococcus pneumoniae : Invasion and Inflammation

Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function

Control of virulence by small RNAs in Streptococcus pneumoniae

Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis

Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex

Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid—CbpA Peptide Recombinant Fusion Protein

Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System

Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis

AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

Genomic Analyses of Pneumococci from Children with Sickle Cell Disease Expose Host-Specific Bacterial Adaptations and Deficits in Current Interventions

Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza

Multi-Valent Protein Hybrid Pneumococcal Vaccines: A Strategy for the Next Generation of Vaccines

Identification of a Candidate Streptococcus pneumoniae Core Genome and Regions of Diversity Correlated with Invasive Pneumococcal Disease

Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster

Microarray Analysis of Pneumococcal Gene Expression during Invasive Disease

Calcium efflux is essential for bacterial survival in the eukaryotic host

The pneumococcus: epidemiology, microbiology, and pathogenesis

β-Arrestin 1 Participates in Platelet-Activating Factor Receptor-Mediated Endocytosis of Streptococcus pneumoniae

Preinfection Systemic Inflammatory Markers and Risk of Hospitalization Due to Pneumonia

Host–pathogen interactions in bacterial meningitis

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