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Pneumolysin: Pathogenesis and Therapeutic Target

Frontiers in microbiology, 2020-07, Vol.11, p.1543-1543

2020

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Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

Nature communications, 2016-02, Vol.7 (1), p.10859-10859, Article 10859

2016

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Streptococcus pneumoniae : Invasion and Inflammation

Microbiology spectrum, 2019-03, Vol.7 (2)

2019

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Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004383-e1004383

2014

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Control of virulence by small RNAs in Streptococcus pneumoniae

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002788-e1002788

2012

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Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children

Frontiers in cellular and infection microbiology, 2020-10, Vol.10, p.585791-585791

Tuomanen, Elaine I

2020

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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Nature immunology, 2008-12, Vol.9 (12), p.1399-1406

2008

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Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis

The Journal of infectious diseases, 2004-11, Vol.190 (9), p.1661-1669

2004

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Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex

mBio, 2023-06, Vol.14 (3), p.e0051023-e0051023

2023

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Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid—CbpA Peptide Recombinant Fusion Protein

The Journal of infectious diseases, 2014-04, Vol.209 (7), p.1116-1125

2014

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Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System

Frontiers in cellular and infection microbiology, 2020-10, Vol.10, p.588378-588378

2020

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Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis

mBio, 2017-01, Vol.8 (1)

2017

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AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness

PloS one, 2016-01, Vol.11 (1), p.e0146785

2016

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Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

The Journal of clinical investigation, 2010-02, Vol.120 (2), p.627-635

2010

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Genomic Analyses of Pneumococci from Children with Sickle Cell Disease Expose Host-Specific Bacterial Adaptations and Deficits in Current Interventions

Cell host & microbe, 2014-05, Vol.15 (5), p.587-599

2014

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Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza

The Journal of infectious diseases, 2011-11, Vol.204 (9), p.1358-1366

2011

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Multi-Valent Protein Hybrid Pneumococcal Vaccines: A Strategy for the Next Generation of Vaccines

Vaccines (Basel), 2021-03, Vol.9 (3), p.209

2021

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Identification of a Candidate Streptococcus pneumoniae Core Genome and Regions of Diversity Correlated with Invasive Pneumococcal Disease

Infection and Immunity, 2006-08, Vol.74 (8), p.4766-4777

2006

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Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster

Nature communications, 2014-11, Vol.5 (1), p.5411-5411, Article 5411

2014

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Microarray Analysis of Pneumococcal Gene Expression during Invasive Disease

Infection and Immunity, 2004-10, Vol.72 (10), p.5582-5596

2004

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Calcium efflux is essential for bacterial survival in the eukaryotic host

Molecular microbiology, 2008-10, Vol.70 (2), p.435-444

2008

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The pneumococcus: epidemiology, microbiology, and pathogenesis

Cold Spring Harbor perspectives in medicine, 2013-07, Vol.3 (7), p.a010215-a010215

2013

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β-Arrestin 1 Participates in Platelet-Activating Factor Receptor-Mediated Endocytosis of Streptococcus pneumoniae

Infection and Immunity, 2005-12, Vol.73 (12), p.7827-7835

2005

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Preinfection Systemic Inflammatory Markers and Risk of Hospitalization Due to Pneumonia

American journal of respiratory and critical care medicine, 2005-12, Vol.172 (11), p.1440-1446

2005

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Host–pathogen interactions in bacterial meningitis

Acta Neuropathologica, 2016-02, Vol.131 (2), p.185-209

2016

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Pneumolysin: Pathogenesis and Therapeutic Target

Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

Streptococcus pneumoniae : Invasion and Inflammation

Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function

Control of virulence by small RNAs in Streptococcus pneumoniae

Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis

Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex

Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid—CbpA Peptide Recombinant Fusion Protein

Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System

Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis

AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

Genomic Analyses of Pneumococci from Children with Sickle Cell Disease Expose Host-Specific Bacterial Adaptations and Deficits in Current Interventions

Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza

Multi-Valent Protein Hybrid Pneumococcal Vaccines: A Strategy for the Next Generation of Vaccines

Identification of a Candidate Streptococcus pneumoniae Core Genome and Regions of Diversity Correlated with Invasive Pneumococcal Disease

Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster

Microarray Analysis of Pneumococcal Gene Expression during Invasive Disease

Calcium efflux is essential for bacterial survival in the eukaryotic host

The pneumococcus: epidemiology, microbiology, and pathogenesis

β-Arrestin 1 Participates in Platelet-Activating Factor Receptor-Mediated Endocytosis of Streptococcus pneumoniae

Preinfection Systemic Inflammatory Markers and Risk of Hospitalization Due to Pneumonia

Host–pathogen interactions in bacterial meningitis

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