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Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs

Genes & development, 2003-03, Vol.17 (6), p.683-710

2003

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Loss of AKAP150 perturbs distinct neuronal processes in mice

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (34), p.12557-12562

2008

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Filanesib plus bortezomib and dexamethasone in relapsed/refractory t(11;14) and 1q21 gain multiple myeloma

Cancer medicine (Malden, MA), 2022-01, Vol.11 (2), p.358-370

2022

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A Phase 1 and 2 study of Filanesib alone and in combination with low‐dose dexamethasone in relapsed/refractory multiple myeloma

Cancer, 2017-12, Vol.123 (23), p.4617-4630

2017

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The Spindle Checkpoint Kinase Bub1 and Cyclin E/Cdk2 Both Contribute to the Establishment of Meiotic Metaphase Arrest by Cytostatic Factor

Current biology, 2002-06, Vol.12 (12), p.1027-1033

2002

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Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520

Molecular cancer therapeutics, 2010-07, Vol.9 (7), p.2046-2056

2010

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A phase 1 dose‐escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma

Cancer, 2016-11, Vol.122 (21), p.3327-3335

2016

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Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220

The Journal of biological chemistry, 2015-08, Vol.290 (32), p.19445-19457

2015

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Tales of how great drugs were brought down by a flawed rationale--letter

Clinical cancer research, 2013-03, Vol.19 (5), p.1302-1302

2013

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The mechanism of CSF arrest in vertebrate oocytes

Molecular and cellular endocrinology, 2002-02, Vol.187 (1), p.173-178

2002

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Spindle Checkpoint Proteins Mad1 and Mad2 Are Required for Cytostatic Factor-Mediated Metaphase Arrest

The Journal of cell biology, 2003-12, Vol.163 (6), p.1231-1242

2003

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Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects

Anticancer research, 2003-01, Vol.23 (1A), p.167

2003

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The pathway of MAP kinase mediation of CSF arrest in Xenopus oocytes

Biology of the Cell, 2001-09, Vol.93 (1), p.27-33

2001

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Bub1 is activated by the protein kinase p90 Rsk during Xenopus oocyte maturation

Current biology, 2001-02, Vol.11 (3), p.141-150

2001

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Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation

Current biology, 2001-02, Vol.11 (3), p.141-150

2001

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ARRY-520, a Novel KSP Inhibitor with Potent Activity in Hematological and Taxane-resistant Tumor Models

Anticancer research, 2009-11, Vol.29 (11), p.4373-4380

2009

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ARRY-520 Combined With Pomalidomide Displays Enhanced Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma

Blood, 2013-11, Vol.122 (21), p.3167-3167

2013

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Filanesib (ARRY-520) Demonstrates Potent and Rapid Activity in Preclinical Models of MM, Dependent on Bcl-2 Family Expression, and Synergistic with Dexamethasone and IMiDs

Blood, 2014-12, Vol.124 (21), p.4710-4710

2014

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Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs

Loss of AKAP150 perturbs distinct neuronal processes in mice

Filanesib plus bortezomib and dexamethasone in relapsed/refractory t(11;14) and 1q21 gain multiple myeloma

A Phase 1 and 2 study of Filanesib alone and in combination with low‐dose dexamethasone in relapsed/refractory multiple myeloma

The Spindle Checkpoint Kinase Bub1 and Cyclin E/Cdk2 Both Contribute to the Establishment of Meiotic Metaphase Arrest by Cytostatic Factor

Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520

A phase 1 dose‐escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma

Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220

Tales of how great drugs were brought down by a flawed rationale--letter

The mechanism of CSF arrest in vertebrate oocytes

Spindle Checkpoint Proteins Mad1 and Mad2 Are Required for Cytostatic Factor-Mediated Metaphase Arrest

Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects

The pathway of MAP kinase mediation of CSF arrest in Xenopus oocytes

Bub1 is activated by the protein kinase p90 Rsk during Xenopus oocyte maturation

Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation

ARRY-520, a Novel KSP Inhibitor with Potent Activity in Hematological and Taxane-resistant Tumor Models

ARRY-520 Combined With Pomalidomide Displays Enhanced Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma

Phase 2 Study of Carfilzomib (CFZ) with or without Filanesib (FIL) in Patients with Advanced Multiple Myeloma (MM)

Filanesib (ARRY-520) Demonstrates Potent and Rapid Activity in Preclinical Models of MM, Dependent on Bcl-2 Family Expression, and Synergistic with Dexamethasone and IMiDs

Identification of Alpha 1-Acid Glycoprotein (AAG) As a Potential Patient Selection Biomarker for Improved Clinical Activity of the Novel KSP Inhibitor ARRY-520 in Relapsed and Refractory Multiple Myeloma (MM)

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