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GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees

Gastroenterology (New York, N.Y. 1943), 2013-06, Vol.144 (7), p.1508-1517.e10

2013

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Pharmacokinetic and pharmacodynamic properties of GS-9620, a novel Toll-like receptor 7 agonist, demonstrate interferon-stimulated gene induction without detectable serum interferon at low oral doses

The Journal of pharmacology and experimental therapeutics, 2014-01, Vol.348 (1), p.96

2014

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Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis

Journal of medicinal chemistry, 2013-09, Vol.56 (18), p.7324-7333

2013

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GS-9219—A Novel Acyclic Nucleotide Analogue with Potent Antineoplastic Activity in Dogs with Spontaneous Non–Hodgkin's Lymphoma

Clinical cancer research, 2008-05, Vol.14 (9), p.2824-2832

2008

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Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B

Journal of hepatology, 2015-06, Vol.62 (6), p.1237-1245

2015

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Assessment of GS-9219 in a Pet Dog Model of Non-Hodgkin's Lymphoma

Clinical cancer research, 2009-05, Vol.15 (10), p.3503-3510

2009

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Targeting DNA Repair in Chronic Lymphocytic Leukemia Cells with a Novel Acyclic Nucleotide Analogue, GS-9219

Clinical cancer research, 2009-06, Vol.15 (11), p.3760-3769

2009

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Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

American Journal of Physiology: Cell Physiology, 2000-12, Vol.279 (6), p.C1733-C1743

2000

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FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

The EMBO journal, 2000-08, Vol.19 (15), p.4046-4055

2000

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Modulation of allergic inflammation in mice deficient in TNF receptors

American journal of physiology. Lung cellular and molecular physiology, 2000-12, Vol.279 (6), p.1047-L1057

2000

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Anti-IgE efficacy in murine asthma models is dependent on the method of allergen sensitization

Journal of allergy and clinical immunology, 2001-06, Vol.107 (6), p.1025-1033

2001

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GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma

BMC veterinary research, 2014-01, Vol.10, p.30-30

2014

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Use of 3'-Deoxy-3'-[¹⁸F]fluorothymidine pet/CT for evaluating response to cytotoxic chemotherapy in dogs with non-HODGKIN'S lymphoma

Veterinary radiology & ultrasound, 2009-11, Vol.50 (6), p.660-668

2009

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Vascular Endothelial-Junctional Adhesion Molecule (VE-JAM)/JAM 2 Interacts with T, NK, and Dendritic Cells Through JAM 3

The Journal of immunology (1950), 2002-02, Vol.168 (4), p.1618-1626

2002

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GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

BMC veterinary research, 2014-01, Vol.10 (1), p.30-30

2014

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Anti-CD11a Ameliorates Disease in the Human Psoriatic Skin–SCID Mouse Transplant Model: Comparison of Antibody to CD11a with Cyclosporin A and Clobetasol Propionate

Laboratory investigation, 2001-09, Vol.81 (9), p.1253-1261

2001

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Long-Term Repopulation of Irradiated Mice With Limiting Numbers of Purified Hematopoietic Stem Cells: In Vivo Expansion of Stem Cell Phenotype But Not Function

Blood, 1995-02, Vol.85 (4), p.1006-1016

1995

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GS-9219 - A Novel Prodrug of the Acyclic Nucleotide PMEG Has Antitumor Activity Against Naive and Melphalan-Refractory Spontaneous Myeloma in Pet Dogs

Blood, 2007-11, Vol.110 (11), p.1508-1508

2007

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GS-9219 - A Novel Prodrug of the Acyclic Nucleotide PMEG Demonstrates Significant Therapeutic Activity Against Spontaneous Non-Hodgkin's Lymphoma as Modeled in Pet Dogs

Blood, 2007-11, Vol.110 (11), p.1380-1380

2007

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ADAPTING PHARMACOKINETIC PROPERTIES OF A HUMANIZED ANTI-INTERLEUKIN-8 ANTIBODY FOR THERAPEUTIC APPLICATIONS USING SITE-SPECIFIC PEGYLATION

Cytokine (Philadelphia, Pa.), 2001-11, Vol.16 (3), p.106-119

2001

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Major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes from horses with equine infectious anemia virus recognize Env and Gag/PR proteins

Journal of Virology, 1994-03, Vol.68 (3), p.1459-1467

1994

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Corticosteroid Immunosuppression and Monoclonal Antibody-mediated CD5+ T Lymphocyte Depletion in Normal and Equine Infectious Anaemia Virus-carrier Horses

Journal of general virology, 1994-05, Vol.75 (5), p.959-968

1994

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Modulation of allergic inflammation in mice deficient in TNF receptors

American journal of physiology. Lung cellular and molecular physiology, 2000-12, Vol.23 (6), p.L1047-L1057

2000

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High-Frequency Cell Surface Expression of a Foreign Protein in Murine Hematopoietic Stem Cells Using a New Retroviral Vector

Blood, 1996-01, Vol.87 (2), p.509-517

1996

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Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

American Journal of Physiology: Cell Physiology, 2000-12, Vol.48 (6), p.C1733-C1743

2000

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GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees

Pharmacokinetic and pharmacodynamic properties of GS-9620, a novel Toll-like receptor 7 agonist, demonstrate interferon-stimulated gene induction without detectable serum interferon at low oral doses

Identification and Optimization of Pteridinone Toll-like Receptor 7 (TLR7) Agonists for the Oral Treatment of Viral Hepatitis

GS-9219—A Novel Acyclic Nucleotide Analogue with Potent Antineoplastic Activity in Dogs with Spontaneous Non–Hodgkin's Lymphoma

Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B

Assessment of GS-9219 in a Pet Dog Model of Non-Hodgkin's Lymphoma

Targeting DNA Repair in Chronic Lymphocytic Leukemia Cells with a Novel Acyclic Nucleotide Analogue, GS-9219

Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

Modulation of allergic inflammation in mice deficient in TNF receptors

Anti-IgE efficacy in murine asthma models is dependent on the method of allergen sensitization

GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma

Use of 3'-Deoxy-3'-[¹⁸F]fluorothymidine pet/CT for evaluating response to cytotoxic chemotherapy in dogs with non-HODGKIN'S lymphoma

Vascular Endothelial-Junctional Adhesion Molecule (VE-JAM)/JAM 2 Interacts with T, NK, and Dendritic Cells Through JAM 3

GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

Anti-CD11a Ameliorates Disease in the Human Psoriatic Skin–SCID Mouse Transplant Model: Comparison of Antibody to CD11a with Cyclosporin A and Clobetasol Propionate

Long-Term Repopulation of Irradiated Mice With Limiting Numbers of Purified Hematopoietic Stem Cells: In Vivo Expansion of Stem Cell Phenotype But Not Function

GS-9219 - A Novel Prodrug of the Acyclic Nucleotide PMEG Has Antitumor Activity Against Naive and Melphalan-Refractory Spontaneous Myeloma in Pet Dogs

GS-9219 - A Novel Prodrug of the Acyclic Nucleotide PMEG Demonstrates Significant Therapeutic Activity Against Spontaneous Non-Hodgkin's Lymphoma as Modeled in Pet Dogs

ADAPTING PHARMACOKINETIC PROPERTIES OF A HUMANIZED ANTI-INTERLEUKIN-8 ANTIBODY FOR THERAPEUTIC APPLICATIONS USING SITE-SPECIFIC PEGYLATION

Major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes from horses with equine infectious anemia virus recognize Env and Gag/PR proteins

Corticosteroid Immunosuppression and Monoclonal Antibody-mediated CD5+ T Lymphocyte Depletion in Normal and Equine Infectious Anaemia Virus-carrier Horses

Modulation of allergic inflammation in mice deficient in TNF receptors

High-Frequency Cell Surface Expression of a Foreign Protein in Murine Hematopoietic Stem Cells Using a New Retroviral Vector

Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation

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