UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Potent, selective, and orally active adenosine A2A receptor antagonists : Arylpiperazine derivatives of pyrazolo[4,3-e]-1,2,4-triazolo[1 ,5-c]pyrimidines

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1376-1380

2007

Volltextzugriff (PDF)

The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510)

The Journal of pharmacology and experimental therapeutics, 2008-08, Vol.326 (2), p.672-682

2008

Volltextzugriff (PDF)

Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models

European journal of pharmacology, 2010-03, Vol.630 (1), p.112-120

2010

Volltextzugriff (PDF)

Where Are the New Cough Treatments: A Debriefing of Recent Clinical Proof-of-Concept Trials with the NOP Agonist SCH 486757

Pharmacology, 2011-01, Vol.88 (1-2), p.50-54

2011

Volltextzugriff (PDF)

6-(2-Furanyl)-9H-purin-2-amine derivatives as A2A adenosine antagonists

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (8), p.2119-2122

2005

Volltextzugriff (PDF)

Synthesis and SAR development of novel P2X₇ receptor antagonists for the treatment of pain: Part 2

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7287-7290

2011

Volltextzugriff (PDF)

The discovery and synthesis of novel adenosine receptor (A 2A) antagonists

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1333-1336

2005

Volltextzugriff (PDF)

Discovery of Orally Active 3-Pyridinyl-tropane As a Potent Nociceptin Receptor Agonist for the Management of Cough

Journal of medicinal chemistry, 2009-09, Vol.52 (17), p.5323-5329

2009

Volltextzugriff (PDF)

Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2281-2284

2007

Volltextzugriff (PDF)

The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety

Bioorganic & medicinal chemistry letters, 2009-05, Vol.19 (9), p.2519-2523

2009

Volltextzugriff (PDF)

Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands: Part 2

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1164-1167

2009

Volltextzugriff (PDF)

Nociceptin inhibits cough in the guinea‐pig by activation of ORL1 receptors

British journal of pharmacology, 2001-03, Vol.132 (6), p.1175-1178

2001

Volltextzugriff (PDF)

Antitussive action of nociceptin in the cat

European journal of pharmacology, 2001-10, Vol.430 (1), p.107-111

2001

Volltextzugriff (PDF)

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs: highly potent, orally active, adenosine A2A antagonists. Part 1

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (16), p.3670-3674

2005

Volltextzugriff (PDF)

SCH-202676: An Allosteric Modulator of Both Agonist and Antagonist Binding to G Protein-Coupled Receptors

Molecular pharmacology, 2001-01, Vol.59 (1), p.30-37

2001

Volltextzugriff (PDF)

3H-[1,2,4] -Triazolo[5,1-i]purin -5 -amine derivatives as adenosine A2A antagonists

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1659-1662

2007

Volltextzugriff (PDF)

Effect of a Novel NOP Receptor Agonist (SCH 225288) on Guinea Pig Irritant-Evoked, Feline Mechanically Induced and Canine Infectious Tracheobronchitis Cough

Pharmacology, 2009-01, Vol.84 (3), p.153-161

2009

Volltextzugriff (PDF)

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: the successful reduction of hERG activity. Part 2

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (16), p.3675-3678

2005

Volltextzugriff (PDF)

Antitussive Effect of Nociceptin/Orphanin FQ in Experimental Cough Models

Pulmonary Pharmacology & Therapeutics, 2002-01, Vol.15 (3), p.213-216

2002

Volltextzugriff (PDF)

Novel pharmacological targets and progression of new antitussive drugs

Expert opinion on therapeutic patents, 2003-10, Vol.13 (10), p.1501-1512

2003

Volltextzugriff (PDF)

Antitussive Profile of the NOP Agonist Ro-64-6198 in the Guinea Pig

Pharmacology, 2004-07, Vol.71 (3), p.143-149

2004

Volltextzugriff (PDF)

Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors

Bioorganic & medicinal chemistry letters, 2016-09, Vol.26 (17), p.4250-4255

2016

Volltextzugriff (PDF)

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.235-239

2012

Volltextzugriff (PDF)

Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation

ACS medicinal chemistry letters, 2015-06, Vol.6 (6), p.677-682

2015

Volltextzugriff (PDF)

Discovery and hit-to-lead optimization of 2,6-diaminopyrimidine inhibitors of interleukin-1 receptor-associated kinase 4

Bioorganic & medicinal chemistry letters, 2015-05, Vol.25 (9), p.1836-1841

2015

Volltextzugriff (PDF)

1 – 25 von 85

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(77)
Mit Volltextzugriff
(82)

Publikationsform

Artikel
(83)
Dissertationen
(2)

Sprache

Englisch
(85)

Erscheinungsjahr

n.n

Thema

Science & Technology
(50)
Life Sciences & Biomedicine
(41)
Pharmacology & Pharmacy
(40)
Animals
(34)
Chemistry
(34)
Physical Sciences
(33)
Chemistry, Organic
(32)
Biological And Medical Sciences
(31)
Medical Sciences
(29)
Structure-Activity Relationship
(29)
Chemistry, Medicinal
(28)
Pharmacology. Drug Treatments
(28)
Humans
(24)
Rats
(23)
Molecular Structure
(16)
Neuropharmacology
(16)
Neurotransmitters. Neurotransmission. Receptors
(15)
Guinea Pigs
(14)
Peptidergic System . Adenosinergic And Purinergic Systems
(14)
Administration, Oral
(13)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Potent, selective, and orally active adenosine A2A receptor antagonists : Arylpiperazine derivatives of pyrazolo[4,3-e]-1,2,4-triazolo[1 ,5-c]pyrimidines

The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510)

Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models

Where Are the New Cough Treatments: A Debriefing of Recent Clinical Proof-of-Concept Trials with the NOP Agonist SCH 486757

6-(2-Furanyl)-9H-purin-2-amine derivatives as A2A adenosine antagonists

Synthesis and SAR development of novel P2X₇ receptor antagonists for the treatment of pain: Part 2

The discovery and synthesis of novel adenosine receptor (A 2A) antagonists

Discovery of Orally Active 3-Pyridinyl-tropane As a Potent Nociceptin Receptor Agonist for the Management of Cough

Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands

The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety

Synthesis and structure–activity relationships of N-substituted spiropiperidines as nociceptin receptor ligands: Part 2

Nociceptin inhibits cough in the guinea‐pig by activation of ORL1 receptors

Antitussive action of nociceptin in the cat

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs: highly potent, orally active, adenosine A2A antagonists. Part 1

SCH-202676: An Allosteric Modulator of Both Agonist and Antagonist Binding to G Protein-Coupled Receptors

3H-[1,2,4] -Triazolo[5,1-i]purin -5 -amine derivatives as adenosine A2A antagonists

Effect of a Novel NOP Receptor Agonist (SCH 225288) on Guinea Pig Irritant-Evoked, Feline Mechanically Induced and Canine Infectious Tracheobronchitis Cough

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: the successful reduction of hERG activity. Part 2

Antitussive Effect of Nociceptin/Orphanin FQ in Experimental Cough Models

Novel pharmacological targets and progression of new antitussive drugs

Antitussive Profile of the NOP Agonist Ro-64-6198 in the Guinea Pig

Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia

Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation

Discovery and hit-to-lead optimization of 2,6-diaminopyrimidine inhibitors of interleukin-1 receptor-associated kinase 4

Suchergebnisse filtern