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Impact of the Pharmaceutical Sciences on Health Care: A Reflection over the Past 50 Years

Journal of pharmaceutical sciences, 2012-11, Vol.101 (11), p.4075-4099

2012

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Contribution of midazolam and its 1-hydroxy metabolite to preoperative sedation in children: a pharmacokinetic-pharmacodynamic analysis

British journal of anaesthesia : BJA, 2002-09, Vol.89 (3), p.428-437

2002

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Development and applications of a physiologically-based model of paediatric oral drug absorption

European journal of pharmaceutical sciences, 2018-03, Vol.115, p.57-67

2018

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Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

European journal of pharmaceutical sciences, 2016-06, Vol.88, p.70-82

2016

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Prediction of time-dependent CYP3A4 drug–drug interactions by physiologically based pharmacokinetic modelling: Impact of inactivation parameters and enzyme turnover

European journal of pharmaceutical sciences, 2011-06, Vol.43 (3), p.160-173

2011

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An evaluation of cytochrome P450 isoform activities in the female dark agouti (DA) rat: Relevance to its use as a model of the CYP2d6 poor metaboliser phenotype

Biochemical pharmacology, 1994-04, Vol.47 (8), p.1295-1307

1994

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PHARAMACOKINETICS OF LOCAL ANAESTHETICS

British journal of anaesthesia : BJA, 1986-07, Vol.58 (7), p.717-731

TUCKER, G.T.

1986

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Determination of midazolam and 1′-hydroxymidazolam by liquid chromatography–mass spectrometry in plasma of patients undergoing methadone maintenance treatment

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-01, Vol.783 (1), p.303-307

2003

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The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6)

Biochemical pharmacology, 1994-03, Vol.47 (7), p.1151-1156

1994

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Journal impact factors: a ‘bioequivalence’ issue?

British journal of clinical pharmacology, 2001-02, Vol.51 (2), p.111-117

2001

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Irreversible binding and metabolism of propranolol by human liver microsomes—Relationship to polymorphic oxidation

Biochemical pharmacology, 1987-07, Vol.36 (14), p.2283-2288

1987

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The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes

British journal of clinical pharmacology, 2004-12, Vol.58 (7), p.S744-S747

2004

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Enantiomer specific pharmacokinetics

Pharmacology & therapeutics (Oxford), 1990, Vol.45 (3), p.309-329

1990

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Assessment of the mouse as an experimental model for studying polymorphic oxidation of the sparteine/debrisoquine type

Biochemical pharmacology, 1991-07, Vol.42 (4), p.947-949

1991

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Analysis of Solvent Central Nervous System Toxicity and Ethanol Interactions Using a Human Population Physiologically Based Kinetic and Dynamic Model

Regulatory toxicology and pharmacology, 2002-04, Vol.35 (2), p.165-176

2002

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The Placebo Response to Citric Acid-induced Cough: Pharmacodynamics and Gender Differences

Pulmonary pharmacology & therapeutics, 2001-01, Vol.14 (4), p.315-319

2001

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Lack of relationships between the debrisoquine (CYP2D6) and mephenytion (CYP2C19) oxidation polymorphisms and susceptibility to breast cancer

Breast (Edinburgh), 1996-08, Vol.5 (4), p.254-258

1996

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The Polymorphic Oxidation of ??-Adrenoceptor Antagonists: Clinical Pharmacokinetic Considerations

Clinical pharmacokinetics, 1986, Vol.11 (1), p.1-17

1986

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The metabolism of tamoxifen by human liver microsomes is not mediated by cytochrome P450IID6

Biochemical pharmacology, 1991-12, Vol.42, p.S209-S212

1991

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PLASMA CONCENTRATIONS OF THE STEREOISOMERS OF PRILOCAINE AFTER ADMINISTRATION OF THE RACEMATE: IMPLICATIONS FOR TOXICITY?

British journal of anaesthesia : BJA, 1990-09, Vol.65 (3), p.333-336

1990

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A lignocaine patch for dental analgesia safety and early pharmacology

Journal of controlled release, 1989-11, Vol.10 (2), p.183-188

1989

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The experimental deign and analysis of in vivo studies of polymorphic drug oxidation

European journal of pharmacology, 1990-07, Vol.183 (1), p.60-61

1990

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Metoprolol oxidation by rat liver microsomes

Biochemical pharmacology, 1986-08, Vol.35 (16), p.2757-2761

1986

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Determination of debrisoquine and its 4-hydroxy metabolite in biological fluids by gas chromatography with flame-ionization and nitrogen-selective detection

Journal of Chromatography A, 1977-03, Vol.133 (1), p.161-166

1977

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Meperidine and Other Basic Drugs: General Method for Their Determination in Plasma

Journal of pharmaceutical sciences, 1974-02, Vol.63 (2), p.306-307

1974

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Impact of the Pharmaceutical Sciences on Health Care: A Reflection over the Past 50 Years

Contribution of midazolam and its 1-hydroxy metabolite to preoperative sedation in children: a pharmacokinetic-pharmacodynamic analysis

Development and applications of a physiologically-based model of paediatric oral drug absorption

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

Prediction of time-dependent CYP3A4 drug–drug interactions by physiologically based pharmacokinetic modelling: Impact of inactivation parameters and enzyme turnover

An evaluation of cytochrome P450 isoform activities in the female dark agouti (DA) rat: Relevance to its use as a model of the CYP2d6 poor metaboliser phenotype

PHARAMACOKINETICS OF LOCAL ANAESTHETICS

Determination of midazolam and 1′-hydroxymidazolam by liquid chromatography–mass spectrometry in plasma of patients undergoing methadone maintenance treatment

The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6)

Journal impact factors: a ‘bioequivalence’ issue?

Irreversible binding and metabolism of propranolol by human liver microsomes—Relationship to polymorphic oxidation

The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes

Enantiomer specific pharmacokinetics

Assessment of the mouse as an experimental model for studying polymorphic oxidation of the sparteine/debrisoquine type

Analysis of Solvent Central Nervous System Toxicity and Ethanol Interactions Using a Human Population Physiologically Based Kinetic and Dynamic Model

The Placebo Response to Citric Acid-induced Cough: Pharmacodynamics and Gender Differences

Lack of relationships between the debrisoquine (CYP2D6) and mephenytion (CYP2C19) oxidation polymorphisms and susceptibility to breast cancer

The Polymorphic Oxidation of ??-Adrenoceptor Antagonists: Clinical Pharmacokinetic Considerations

The metabolism of tamoxifen by human liver microsomes is not mediated by cytochrome P450IID6

PLASMA CONCENTRATIONS OF THE STEREOISOMERS OF PRILOCAINE AFTER ADMINISTRATION OF THE RACEMATE: IMPLICATIONS FOR TOXICITY?

A lignocaine patch for dental analgesia safety and early pharmacology

The experimental deign and analysis of in vivo studies of polymorphic drug oxidation

Metoprolol oxidation by rat liver microsomes

Determination of debrisoquine and its 4-hydroxy metabolite in biological fluids by gas chromatography with flame-ionization and nitrogen-selective detection

Meperidine and Other Basic Drugs: General Method for Their Determination in Plasma

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