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Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (23), p.11418-11427

2019

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The relationship between the chemistry and biological activity of the bisphosphonates

Bone (New York, N.Y.), 2011-07, Vol.49 (1), p.20-33

2011

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How do we sense phosphate to regulate serum phosphate level?

Journal of bone and mineral metabolism, 2020-01, Vol.38 (1), p.1-6

2020

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Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis

Nature communications, 2022-11, Vol.13 (1), p.7194-7194, Article 7194

2022

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Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases

EBioMedicine, 2019-07, Vol.45, p.630-645

2019

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Dystrobrevin alpha gene is a direct target of the vitamin D receptor in muscle

Journal of molecular endocrinology, 2020-04, Vol.64 (3), p.195-208

2020

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How do we sense phosphate to regulate serum phosphate level?

Journal of bone and mineral metabolism, 2020, Vol.38 (1), p.1-6

2020

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The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1‐Fluoro‐2‐(Imidazo‐[1,2‐α]Pyridin‐3‐yl)‐Ethyl‐Bisphosphonate)

Journal of bone and mineral research, 2017-09, Vol.32 (9), p.1860-1869

2017

Volltextzugriff (PDF)

Scavenger Receptor Class A1 Mediates Uptake of Morpholino Antisense Oligonucleotide into Dystrophic Skeletal Muscle

Molecular therapy. Nucleic acids, 2019-03, Vol.14, p.520-535

2019

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The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants

Bone (New York, N.Y.), 2015-12, Vol.81, p.478-486

2015

Volltextzugriff (PDF)

Harnessing ceramic hydroxyapatite as an effective polishing strategy to remove product- and process-related impurities in bispecific antibody purification

Bioresources and bioprocessing, 2023-12, Vol.10 (1), p.93-93, Article 93

2023

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In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1828, p.151

2018

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BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO

Bone (New York, N.Y.), 2010, Vol.46, p.S63-S64

2010

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Designed mutants of human farnesyl pyrophosphate synthase (FPPS) help to characterise the interactions of nitrogen-containing bisphosphonates with Tyrosine 204 and Phenylalanine 239 side-chain residues

Bone (New York, N.Y.), 2010, Vol.46, p.S23-S23

2010

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Targeting the mevalonate pathway for pharmacological intervention

Tsoumpra, Maria

2011

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Antiresorptives

The Duration and Safety of Osteoporosis Treatment, 2016, p.17-36

2016

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Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation

The relationship between the chemistry and biological activity of the bisphosphonates

How do we sense phosphate to regulate serum phosphate level?

Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis

Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases

Dystrobrevin alpha gene is a direct target of the vitamin D receptor in muscle

How do we sense phosphate to regulate serum phosphate level?

The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1‐Fluoro‐2‐(Imidazo‐[1,2‐α]Pyridin‐3‐yl)‐Ethyl‐Bisphosphonate)

Scavenger Receptor Class A1 Mediates Uptake of Morpholino Antisense Oligonucleotide into Dystrophic Skeletal Muscle

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants

Harnessing ceramic hydroxyapatite as an effective polishing strategy to remove product- and process-related impurities in bispecific antibody purification

In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient

BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO

Designed mutants of human farnesyl pyrophosphate synthase (FPPS) help to characterise the interactions of nitrogen-containing bisphosphonates with Tyrosine 204 and Phenylalanine 239 side-chain residues

Targeting the mevalonate pathway for pharmacological intervention

Antiresorptives

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