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Regulatory T cells in the treatment of disease

Nature reviews. Drug discovery, 2018-11, Vol.17 (11), p.823-844

2018

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Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells

Nature communications, 2020-06, Vol.11 (1), p.2859-12, Article 2859

2020

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Lymphocytes in the neighborhood: good or bad for the kidney?

The Journal of clinical investigation, 2022-07, Vol.132 (13)

2022

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Cell‐Derived Extracellular Matrix‐Rich Biomimetic Substrate Supports Podocyte Proliferation, Differentiation, and Maintenance of Native Phenotype

Advanced functional materials, 2020-10, Vol.30 (44), p.n/a

2020

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Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation

Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (37), p.9288-9293

2018

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CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses

Nature communications, 2024-01, Vol.15 (1), p.840-11, Article 840

2024

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The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway

The Journal of immunology (1950), 2021-04, Vol.206 (8), p.1719-1728

2021

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Phosphatase PP2A is requisite for the function of regulatory T cells

Nature immunology, 2016-05, Vol.17 (5), p.556-564

2016

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CD38 in SLE CD4 T cells promotes Ca2+ flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane

Nature communications, 2024-09, Vol.15 (1), p.8304-18, Article 8304

2024

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The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity

Cell reports (Cambridge), 2024-07, Vol.43 (7), p.114379, Article 114379

2024

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IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation

The Journal of clinical investigation, 2021-06, Vol.131 (12)

2021

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PPP2R2D Suppresses Effector T Cell Exhaustion and Regulatory T Cell Expansion and Inhibits Tumor Growth in Melanoma

The Journal of immunology (1950), 2022-08, Vol.209 (3), p.621-628

2022

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Activation of classical and alternative complement pathways in the pathogenesis of lung injury in COVID-19

Clinical immunology (Orlando, Fla.), 2021-05, Vol.226, p.108716-108716, Article 108716

2021

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CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease

The Journal of clinical investigation, 2018-08, Vol.128 (8), p.3445-3459

2018

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N‐glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury

American journal of transplantation, 2021-01, Vol.21 (1), p.148-160

2021

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Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis

Rheumatology (Oxford, England), 2023-02, Vol.62 (2), p.861-871

2023

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Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells

Frontiers in immunology, 2018-10, Vol.9, p.2113-2113

2018

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Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis

JCI insight, 2021-05, Vol.6 (9)

2021

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Complement and coagulation cascades in trauma

Acute medicine & surgery, 2019-10, Vol.6 (4), p.329-335

2019

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IL-27 attenuates IL-23 mediated inflammatory arthritis

Clinical immunology (Orlando, Fla.), 2023-06, Vol.251, p.109327-109327, Article 109327

2023

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Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia

The Journal of immunology (1950), 2017-01, Vol.198 (2), p.788-797

2017

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Complement activation and increased expression of Syk, mucin-1 and CaMK4 in kidneys of patients with COVID-19

Clinical immunology (Orlando, Fla.), 2021-08, Vol.229, p.108795-108795, Article 108795

2021

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Reduction of MDSCs with All-trans Retinoic Acid Improves CAR Therapy Efficacy for Sarcomas

Cancer immunology research, 2016-10, Vol.4 (10), p.869-880

2016

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Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation

JCI insight, 2019-06, Vol.4 (12)

2019

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role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3374-3379

2008

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Regulatory T cells in the treatment of disease

Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells

Lymphocytes in the neighborhood: good or bad for the kidney?

Cell‐Derived Extracellular Matrix‐Rich Biomimetic Substrate Supports Podocyte Proliferation, Differentiation, and Maintenance of Native Phenotype

Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation

CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses

The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway

Phosphatase PP2A is requisite for the function of regulatory T cells

CD38 in SLE CD4 T cells promotes Ca2+ flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane

The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity

IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation

PPP2R2D Suppresses Effector T Cell Exhaustion and Regulatory T Cell Expansion and Inhibits Tumor Growth in Melanoma

Activation of classical and alternative complement pathways in the pathogenesis of lung injury in COVID-19

CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease

N‐glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury

Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: dual effect on Th17 cell activation and osteoclastogenesis

Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells

Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis

Complement and coagulation cascades in trauma

IL-27 attenuates IL-23 mediated inflammatory arthritis

Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia

Complement activation and increased expression of Syk, mucin-1 and CaMK4 in kidneys of patients with COVID-19

Reduction of MDSCs with All-trans Retinoic Acid Improves CAR Therapy Efficacy for Sarcomas

Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation

role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

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