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Modeling, Analysis, and Validation of a Novel HIV Integrase Structure Provide Insights into the Binding Modes of Potent Integrase Inhibitors

Journal of molecular biology, 2008-07, Vol.380 (3), p.504-519

2008

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Biphasic clearance kinetics of hepatitis B virus from patients during adefovir dipivoxil therapy

Hepatology (Baltimore, Md.), 1999-06, Vol.29 (6), p.1863-1869

1999

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Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Antimicrobial agents and chemotherapy, 2016-12, Vol.60 (12), p.7086-7097

2016

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Cyanotriazoles activate latent HIV and strongly synergize with proteasome inhibitors ex vivo in resting CD4 T cells from suppressed HIV + donors

Journal of Virus Eradication, 2015-12, Vol.1, p.12-12

2015

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Regulation of Thrombomodulin by Tumor Necrosis Factor-α: Comparison of Transcriptional and Posttranscriptional Mechanisms

Blood, 1991-02, Vol.77 (3), p.542-550

1991

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Protein Engineering Thrombin for Optimal Specificity and Potency of Anticoagulant Activity in Vivo

Biochemistry (Easton), 1996-12, Vol.35 (51), p.16449-16457

1996

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Conversion of thrombin into an anticoagulant by protein engineering

Nature (London), 1995-11, Vol.378 (6555), p.413-416

1995

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Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite

The Journal of biological chemistry, 1992-12, Vol.267 (34), p.24408-24412

1992

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Single Amino Acid Substitutions Dissociate Fibrinogen-Clotting and Thrombomodulin-Binding Activities of Human Thrombin

Proceedings of the National Academy of Sciences - PNAS, 1991-08, Vol.88 (15), p.6775-6779

1991

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Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity

The Journal of biological chemistry, 1992-03, Vol.267 (9), p.6164-6170

1992

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HIV-1 Integrase Preassembled on Donor DNA Is Refractory to Activity Stimulation by LEDGF/p75

Biochemistry (Easton), 2007-03, Vol.46 (10), p.2899-2908

2007

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Combination therapy with lamivudine and famciclovir for chronic hepatitis B–infected Chinese patients: A viral dynamics study

Hepatology (Baltimore, Md.), 2000-08, Vol.32 (2), p.394-399

2000

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Biochemical characterization of rhinovirus RNA-dependent RNA polymerase

Antiviral research, 2002-11, Vol.56 (2), p.99-114

2002

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Functional Mapping of the Surface Residues of Human Thrombin ()

The Journal of biological chemistry, 1995-07, Vol.270 (28), p.16854-16863

1995

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Effects of 5'-terminal modifications on the biological activity of defective interfering RNAs of Sindbis virus

Journal of Virology, 1988-01, Vol.62 (1), p.47-53

1988

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Ligand specificity of human thrombomodulin. Equilibrium binding of human thrombin, meizothrombin, and factor Xa to recombinant thrombomodulin

The Journal of biological chemistry, 1992-04, Vol.267 (10), p.7083-7088

1992

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Acute vocal fold dystonic reaction to propofol: a case report

American journal of otolaryngology, 2015-03, Vol.36 (2), p.303-305

2015

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Functional Requirements for Inhibition of Thrombin by Antithrombin III in the Presence and Absence of Heparin

The Journal of biological chemistry, 1997-05, Vol.272 (18), p.12024-12029

1997

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Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics

The Journal of biological chemistry, 1995-08, Vol.270 (33), p.19370-19376

1995

Volltextzugriff (PDF)

Predicting HBEAG loss by HBV DNA early kinetics and HBV genotype during treatment of HBEAG+ chronic hepatitis B (CHB) patients with adefovir dipivoxil (ADV)

Journal of hepatology, 2003-04, Vol.38, p.26-26

2003

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Effect of superior oblique weakening on vertical alignment and horizontal and vertical incomitance in patients with A-pattern strabismus

Journal of AAPOS, 2011-02, Vol.15 (1), p.9-13

2011

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Equilibrium binding of thrombin to recombinant human thrombomodulin: effect of hirudin, fibrinogen, factor Va, and peptide analogs

Biochemistry (Easton), 1990-11, Vol.29 (47), p.10602-10612

1990

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Tailoring viscoelastic and mechanical properties of the foamed blends of EVA and various ethylene-styrene interpolymers

Polymer composites, 2003-06, Vol.24 (3), p.304-313

2003

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Dynamics analyses provide insight into the influence of precore mutations on the mechanisms of viral CL

Journal of hepatology, 2001-04, Vol.34, p.167-168

2001

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Deletion mapping of sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging

Cell, 1986-01, Vol.44 (1), p.137-145

1986

Volltextzugriff (PDF)

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Modeling, Analysis, and Validation of a Novel HIV Integrase Structure Provide Insights into the Binding Modes of Potent Integrase Inhibitors

Biphasic clearance kinetics of hepatitis B virus from patients during adefovir dipivoxil therapy

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Cyanotriazoles activate latent HIV and strongly synergize with proteasome inhibitors ex vivo in resting CD4 T cells from suppressed HIV + donors

Regulation of Thrombomodulin by Tumor Necrosis Factor-α: Comparison of Transcriptional and Posttranscriptional Mechanisms

Protein Engineering Thrombin for Optimal Specificity and Potency of Anticoagulant Activity in Vivo

Conversion of thrombin into an anticoagulant by protein engineering

Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite

Single Amino Acid Substitutions Dissociate Fibrinogen-Clotting and Thrombomodulin-Binding Activities of Human Thrombin

Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity

HIV-1 Integrase Preassembled on Donor DNA Is Refractory to Activity Stimulation by LEDGF/p75

Combination therapy with lamivudine and famciclovir for chronic hepatitis B–infected Chinese patients: A viral dynamics study

Biochemical characterization of rhinovirus RNA-dependent RNA polymerase

Functional Mapping of the Surface Residues of Human Thrombin ()

Effects of 5'-terminal modifications on the biological activity of defective interfering RNAs of Sindbis virus

Ligand specificity of human thrombomodulin. Equilibrium binding of human thrombin, meizothrombin, and factor Xa to recombinant thrombomodulin

Acute vocal fold dystonic reaction to propofol: a case report

Functional Requirements for Inhibition of Thrombin by Antithrombin III in the Presence and Absence of Heparin

Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics

Predicting HBEAG loss by HBV DNA early kinetics and HBV genotype during treatment of HBEAG+ chronic hepatitis B (CHB) patients with adefovir dipivoxil (ADV)

Effect of superior oblique weakening on vertical alignment and horizontal and vertical incomitance in patients with A-pattern strabismus

Equilibrium binding of thrombin to recombinant human thrombomodulin: effect of hirudin, fibrinogen, factor Va, and peptide analogs

Tailoring viscoelastic and mechanical properties of the foamed blends of EVA and various ethylene-styrene interpolymers

Dynamics analyses provide insight into the influence of precore mutations on the mechanisms of viral CL

Deletion mapping of sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging

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