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Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor

PloS one, 2023-06, Vol.18 (6), p.e0285221

2023

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A novel pseudovirus-based mouse model of SARS-CoV-2 infection to test COVID-19 interventions

Journal of biomedical science, 2021-04, Vol.28 (1), p.34-34, Article 34

2021

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Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors

PloS one, 2021-09, Vol.16 (9), p.e0256937-e0256937

2021

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Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity

Journal of biomedical science, 2022-08, Vol.29 (1), p.1-57, Article 57

2022

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Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine

Journal of biomedical science, 2021-09, Vol.28 (1), p.63-63, Article 63

2021

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In vivo characterization of emerging SARS-CoV-2 variant infectivity and human antibody escape potential

Cell reports (Cambridge), 2021-10, Vol.37 (3), p.109838-109838, Article 109838

2021

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Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties

PloS one, 2020-01, Vol.15 (1), p.e0227727

2020

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Virus-like particle vaccine displaying an external, membrane adjacent MUC16 epitope elicits ovarian cancer-reactive antibodies

Journal of ovarian research, 2024-01, Vol.17 (1), p.19-19, Article 19

2024

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Albumin and interferon-β fusion protein serves as an effective vaccine adjuvant to enhance antigen-specific CD8+ T cell-mediated antitumor immunity

Journal for immunotherapy of cancer, 2022-04, Vol.10 (4), p.e004342

2022

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TLR9 acts as a sensor for tumor-released DNA to modulate anti-tumor immunity after chemotherapy

Journal for immunotherapy of cancer, 2019-10, Vol.7 (1), p.260-260, Article 260

2019

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RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells

Oncotarget, 2016-10, Vol.7 (42), p.68489-68502

2016

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Co-targeting of multiple microRNAs on factor-Inhibiting hypoxia-Inducible factor gene for the pathogenesis of head and neck carcinomas

Head & neck, 2016-04, Vol.38 (4), p.522-528

2016

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Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis

Journal for immunotherapy of cancer, 2020-02, Vol.8 (1), p.e000480

2020

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Development of a Novel Mouse Model of Spontaneous High-Risk HPVE6/E7-Expressing Carcinoma in the Cervicovaginal Tract

Cancer research (Chicago, Ill.), 2021-09, Vol.81 (17), p.4560-4569

2021

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Preclinical studies of RA475, a guanidine-substituted spirocyclic candidate RPN13/ADRM1 inhibitor for treatment of ovarian cancer

PloS one, 2024-07, Vol.19 (7), p.e0305710

2024

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In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

The Journal of clinical investigation, 2024-01, Vol.134 (1)

2024

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Bioinformatics and in vitro experimental analyses identify the selective therapeutic potential of interferon gamma and apigenin against cervical squamous cell carcinoma and adenocarcinoma

Oncotarget, 2017-07, Vol.8 (28), p.46145-46162

2017

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NKG2D-Fc fusion protein promotes antitumor immunity through the depletion of immunosuppressive cells

Cancer Immunology, Immunotherapy, 2020-10, Vol.69 (10), p.2147-2155

2020

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K14‐EGFP‐miR‐31 transgenic mice have high susceptibility to chemical‐induced squamous cell tumorigenesis that is associating with Ku80 repression

International journal of cancer, 2015-03, Vol.136 (6), p.1263-1275

2015

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Up-regulation of miR-187 modulates the advances of oral carcinoma by targeting BARX2 tumor suppressor

Oncotarget, 2016-09, Vol.7 (38), p.61355-61365

2016

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Protein detection in blood with single-molecule imaging

Science advances, 2021-08, Vol.7 (33)

2021

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Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16 + Oral Tumors and Immunologic Control

Cancer immunology research, 2018-03, Vol.6 (3), p.305-319

2018

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In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

The Journal of clinical investigation, 2024-01, Vol.134 (1), p.1-16

2024

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Abstract 5468: Transgenic mice ectopically express miR-31 in basal keratinocyte, exhibit high potential for oral tumorigenesis

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5468-5468

2012

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Abstract 2733: K14-GFP-miR-31 transgenic mice confer high susceptibility to squamous cell tumorigenesis on oral tongue and esophagus

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2733-2733

2013

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Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor

A novel pseudovirus-based mouse model of SARS-CoV-2 infection to test COVID-19 interventions

Chirality and asymmetry increase the potency of candidate ADRM1/RPN13 inhibitors

Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity

Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine

In vivo characterization of emerging SARS-CoV-2 variant infectivity and human antibody escape potential

Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties

Virus-like particle vaccine displaying an external, membrane adjacent MUC16 epitope elicits ovarian cancer-reactive antibodies

Albumin and interferon-β fusion protein serves as an effective vaccine adjuvant to enhance antigen-specific CD8+ T cell-mediated antitumor immunity

TLR9 acts as a sensor for tumor-released DNA to modulate anti-tumor immunity after chemotherapy

RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells

Co-targeting of multiple microRNAs on factor-Inhibiting hypoxia-Inducible factor gene for the pathogenesis of head and neck carcinomas

Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis

Development of a Novel Mouse Model of Spontaneous High-Risk HPVE6/E7-Expressing Carcinoma in the Cervicovaginal Tract

Preclinical studies of RA475, a guanidine-substituted spirocyclic candidate RPN13/ADRM1 inhibitor for treatment of ovarian cancer

In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

Bioinformatics and in vitro experimental analyses identify the selective therapeutic potential of interferon gamma and apigenin against cervical squamous cell carcinoma and adenocarcinoma

NKG2D-Fc fusion protein promotes antitumor immunity through the depletion of immunosuppressive cells

K14‐EGFP‐miR‐31 transgenic mice have high susceptibility to chemical‐induced squamous cell tumorigenesis that is associating with Ku80 repression

Up-regulation of miR-187 modulates the advances of oral carcinoma by targeting BARX2 tumor suppressor

Protein detection in blood with single-molecule imaging

Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16 + Oral Tumors and Immunologic Control

In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

Abstract 5468: Transgenic mice ectopically express miR-31 in basal keratinocyte, exhibit high potential for oral tumorigenesis

Abstract 2733: K14-GFP-miR-31 transgenic mice confer high susceptibility to squamous cell tumorigenesis on oral tongue and esophagus

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