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A Simple, High-Resolution Method for Establishing DNA Binding Affinity and Sequence Selectivity

Journal of the American Chemical Society, 2001-06, Vol.123 (25), p.5878-5891

2001

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Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent

Molecular pharmaceutics, 2023-12, Vol.20 (12), p.6213-6225

2023

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A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity

Accounts of chemical research, 2004-01, Vol.37 (1), p.61-69

2004

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The Allyl Leaving Group Approach to Tricoordinate Silyl, Germyl, and Stannyl Cations

Journal of the American Chemical Society, 1999-06, Vol.121 (21), p.5001-5008

1999

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High-resolution assessment of protein DNA binding affinity and selectivity utilizing a fluorescent intercalator displacement (FID) assay

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3805-3807

2003

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Comprehensive high-Resolution analysis of hairpin polyamides utilizing a fluorescent intercalator displacement (FID) assay

Bioorganic & medicinal chemistry, 2003-10, Vol.11 (20), p.4479-4486

2003

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539. GS-CA2: A Novel, Potent, and Selective First-In-class Inhibitor of HIV-1 Capsid Function Displays Nonclinical Pharmacokinetics Supporting Long-Acting Potential in Humans

Open forum infectious diseases, 2018-11, Vol.5 (suppl_1), p.S199-S200

2018

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Thiazole orange as the fluorescent intercalator in a high resolution fid assay for determining DNA binding affinity and sequence selectivity of small molecules

Bioorganic & medicinal chemistry, 2001-09, Vol.9 (9), p.2511-2518

2001

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Total Syntheses of Thiocoraline and BE-22179 and Assessment of Their DNA Binding and Biological Properties

Journal of the American Chemical Society, 2001-01, Vol.123 (4), p.561-568

2001

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Clinical targeting of HIV capsid protein with a long-acting small molecule

Nature (London), 2020-08, Vol.584 (7822), p.614

2020

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Determination of binding affinities of triplex forming oligonucleotides using a fluorescent intercalator displacement (FID) assay

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3801-3804

2003

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Synthesis and evaluation of a novel bleomycin A2 analogue: continuing assessment of the linker domain

Tetrahedron letters, 2000-12, Vol.41 (49), p.9493-9498

2000

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Sequence-Selective DNA Recognition: Natural Products and Nature’s Lessons

Chemistry & biology, 2004-12, Vol.11 (12), p.1607-1617

2004

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A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity

Current Protocols in Nucleic Acid Chemistry, 2005-04, Vol.20 (1), p.8.5.1-8.5.11

2005

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Torsional distortions in trimesitylsilanes and trimesitylgermanes

Journal of organometallic chemistry, 1998-10, Vol.568 (1), p.21-31

1998

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Bifunctional alkylating agents derived from duocarmycin SA: potent antitumor activity with altered sequence selectivity

Bioorganic & medicinal chemistry letters, 2000-03, Vol.10 (5), p.495-498

2000

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Synthesis and evaluation of a novel bleomycin A 2 analogue: continuing assessment of the linker domain

Tetrahedron letters, 2000, Vol.41 (49), p.9493-9498

2000

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A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity

ChemInform, 2004-04, Vol.35 (16), p.no-no

2004

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ChemInform Abstract: Bifunctional Alkylating Agents Derived from Duocarmycin SA: Potent Antitumor Activity with Altered Sequence Selectivity

ChemInform, 2000-07, Vol.31 (28), p.no-no

2000

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ChemInform Abstract: The Allyl Leaving Group Approach to Tricoordinate Silyl, Germyl, and Stannyl Cations

ChemInform, 1999-08, Vol.30 (35), p.no-no

1999

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Oral vs Intravenous Antibiotics for Patients With Klebsiella pneumoniae Liver Abscess: A Randomized, Controlled Noninferiority Study

Clinical infectious diseases, 2020-08, Vol.71 (4), p.952-959

2020

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A novel gene homologous to teashirt is differentially expressed in neonatal mouse skin during development of hair follicles

Molecular biotechnology, 2004-09, Vol.28 (1), p.9-20

2004

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Mouse keratinocytes express c98, a novel gene homologous to bcl-2, that is stimulated by insulin-like growth factor 1 and prevents dexamethasone-induced apoptosis

Biochimica et biophysica acta, 2004-01, Vol.1676 (2), p.127-137

2004

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A Simple, High-Resolution Method for Establishing DNA Binding Affinity and Sequence Selectivity

A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model

Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent

A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity

The Allyl Leaving Group Approach to Tricoordinate Silyl, Germyl, and Stannyl Cations

High-resolution assessment of protein DNA binding affinity and selectivity utilizing a fluorescent intercalator displacement (FID) assay

Comprehensive high-Resolution analysis of hairpin polyamides utilizing a fluorescent intercalator displacement (FID) assay

539. GS-CA2: A Novel, Potent, and Selective First-In-class Inhibitor of HIV-1 Capsid Function Displays Nonclinical Pharmacokinetics Supporting Long-Acting Potential in Humans

Thiazole orange as the fluorescent intercalator in a high resolution fid assay for determining DNA binding affinity and sequence selectivity of small molecules

Total Syntheses of Thiocoraline and BE-22179 and Assessment of Their DNA Binding and Biological Properties

Clinical targeting of HIV capsid protein with a long-acting small molecule

Determination of binding affinities of triplex forming oligonucleotides using a fluorescent intercalator displacement (FID) assay

Synthesis and evaluation of a novel bleomycin A2 analogue: continuing assessment of the linker domain

Sequence-Selective DNA Recognition: Natural Products and Nature’s Lessons

A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity

Torsional distortions in trimesitylsilanes and trimesitylgermanes

Bifunctional alkylating agents derived from duocarmycin SA: potent antitumor activity with altered sequence selectivity

Synthesis and evaluation of a novel bleomycin A 2 analogue: continuing assessment of the linker domain

A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity

ChemInform Abstract: Bifunctional Alkylating Agents Derived from Duocarmycin SA: Potent Antitumor Activity with Altered Sequence Selectivity

ChemInform Abstract: The Allyl Leaving Group Approach to Tricoordinate Silyl, Germyl, and Stannyl Cations

Oral vs Intravenous Antibiotics for Patients With Klebsiella pneumoniae Liver Abscess: A Randomized, Controlled Noninferiority Study

A novel gene homologous to teashirt is differentially expressed in neonatal mouse skin during development of hair follicles

Mouse keratinocytes express c98, a novel gene homologous to bcl-2, that is stimulated by insulin-like growth factor 1 and prevents dexamethasone-induced apoptosis

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