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Amyloid beta induces Fmr1‐dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2

Journal of cellular physiology, 2022-07, Vol.237 (7), p.2929-2942

2022

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E3 ubiquitin ligase Nedd4‐2 exerts neuroprotective effects during endoplasmic reticulum stress

Journal of neurochemistry, 2022-03, Vol.160 (6), p.613-624

2022

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C2‐lacking isoform of Nedd4‐2 regulates excitatory synaptic strength through GluA1 ubiquitination‐independent mechanisms

Journal of neurochemistry, 2019-11, Vol.151 (3), p.289-300

2019

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The tumor suppressor p53 guides GluA1 homeostasis through Nedd4‐2 during chronic elevation of neuronal activity

Journal of neurochemistry, 2015-10, Vol.135 (2), p.226-233

2015

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Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4‐2 in translational suppression during ER stress

Journal of neurochemistry, 2021-06, Vol.157 (6), p.1809-1820

2021

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Infantile spasms‐linked Nedd4‐2 mediates hippocampal plasticity and learning via cofilin signaling

EMBO reports, 2021-10, Vol.22 (10), p.e52645-n/a

2021

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ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model

Neurobiology of disease, 2021-10, Vol.158, p.105450-105450, Article 105450

2021

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Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation

PLoS genetics, 2019-09, Vol.15 (9), p.e1008364-e1008364

2019

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Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors

PLoS genetics, 2017-02, Vol.13 (2), p.e1006634-e1006634

2017

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Hyperexcitability and Homeostasis in Fragile X Syndrome

Frontiers in molecular neuroscience, 2022-01, Vol.14, p.805929-805929

2022

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mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS

EMBO molecular medicine, 2024-03, Vol.16 (3), p.506-522

2024

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Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy

Neurobiology of disease, 2018-10, Vol.118, p.76-93

2018

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Ubiquitination and E3 Ubiquitin Ligases in Rare Neurological Diseases with Comorbid Epilepsy

Neuroscience, 2020-01, Vol.428, p.90-99

2020

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Regulation of stress granule dynamics by Grb7 and FAK signalling pathway

The EMBO journal, 2008-03, Vol.27 (5), p.715-726

2008

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Ubiquitin proteasome system-mediated degradation of synaptic proteins: An update from the postsynaptic side

Biochimica et biophysica acta. Molecular cell research, 2014-12, Vol.1843 (12), p.2838-2842

Tsai, Nien-Pei

2014

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A Role for Dendritic mGluR5-Mediated Local Translation of Arc/Arg3.1 in MEF2-Dependent Synapse Elimination

Cell reports (Cambridge), 2014-06, Vol.7 (5), p.1589-1600

2014

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Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation

The EMBO journal, 2006-11, Vol.25 (21), p.5094-5104

2006

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Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology

EMBO reports, 2024-03, Vol.25 (3), p.1233-1255

2024

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Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2

Human molecular genetics, 2018-08, Vol.27 (16), p.2805-2816

2018

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Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning

Molecular psychiatry, 2023-09, Vol.28 (9), p.3782-3794

2023

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Dual action of epidermal growth factor: extracellular signal-stimulated nuclear-cytoplasmic export and coordinated translation of selected messenger RNA

The Journal of cell biology, 2010-02, Vol.188 (3), p.325-333

2010

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Axonal mRNA transport and localized translational regulation of κ-opioid receptor in primary neurons of dorsal root ganglia

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (52), p.19919-19924

2006

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Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

Cell, 2012-12, Vol.151 (7), p.1581-1594

2012

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Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (32), p.11424-11429

2008

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Copb1-Facilitated Axonal Transport and Translation of κ Opioid-Receptor mRNA

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (34), p.13810-13815

2007

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Amyloid beta induces Fmr1‐dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2

E3 ubiquitin ligase Nedd4‐2 exerts neuroprotective effects during endoplasmic reticulum stress

C2‐lacking isoform of Nedd4‐2 regulates excitatory synaptic strength through GluA1 ubiquitination‐independent mechanisms

The tumor suppressor p53 guides GluA1 homeostasis through Nedd4‐2 during chronic elevation of neuronal activity

Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4‐2 in translational suppression during ER stress

Infantile spasms‐linked Nedd4‐2 mediates hippocampal plasticity and learning via cofilin signaling

ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model

Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation

Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors

Hyperexcitability and Homeostasis in Fragile X Syndrome

mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS

Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy

Ubiquitination and E3 Ubiquitin Ligases in Rare Neurological Diseases with Comorbid Epilepsy

Regulation of stress granule dynamics by Grb7 and FAK signalling pathway

Ubiquitin proteasome system-mediated degradation of synaptic proteins: An update from the postsynaptic side

A Role for Dendritic mGluR5-Mediated Local Translation of Arc/Arg3.1 in MEF2-Dependent Synapse Elimination

Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation

Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology

Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2

Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning

Dual action of epidermal growth factor: extracellular signal-stimulated nuclear-cytoplasmic export and coordinated translation of selected messenger RNA

Axonal mRNA transport and localized translational regulation of κ-opioid receptor in primary neurons of dorsal root ganglia

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression

Copb1-Facilitated Axonal Transport and Translation of κ Opioid-Receptor mRNA

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