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Role of the ERK pathway in psychostimulant-induced locomotor sensitization

BMC neuroscience, 2006-03, Vol.7 (1), p.20-20, Article 20

2006

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Aggrecan Protects Cartilage Collagen from Proteolytic Cleavage

The Journal of biological chemistry, 2003-11, Vol.278 (46), p.45539-45545

2003

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Cyclooxygenase-2 Differentially Directs Uterine Angiogenesis during Implantation in Mice

The Journal of biological chemistry, 2002-08, Vol.277 (32), p.29260-29267

2002

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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II

Nature (London), 1995-11, Vol.378 (6555), p.406-409

1995

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Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis

The Journal of pharmacology and experimental therapeutics, 2003-01, Vol.304 (1), p.172

2003

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Inhibition of MAP Kinase Kinase Prevents Cytokine and Prostaglandin E2 Production in Lipopolysaccharide-Stimulated Monocytes

The Journal of immunology (1950), 1998-11, Vol.161 (10), p.5681-5686

1998

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Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation

The Journal of pharmacology and experimental therapeutics, 2006-07, Vol.318 (1), p.411

2006

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Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (16), p.6846-6851

2007

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In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis

Journal of the American Society of Nephrology, 2002-06, Vol.13 (6), p.1473-1480

2002

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The MAPK cascade is required for mammalian associative learning

Nature neuroscience, , Vol.1 (7), p.602-609

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Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice

Cell, 1997-10, Vol.91 (2), p.197-208

1997

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Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

The Journal of biological chemistry, 1998-07, Vol.273 (29), p.18623-18632

1998

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A necessity for MAP kinase activation in mammalian spatial learning

Learning & memory (Cold Spring Harbor, N.Y.), 1999-09, Vol.6 (5), p.478-490

1999

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Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1577-1582

2008

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Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks T Cell Proliferation But Does Not Induce or Prevent Anergy

The Journal of immunology (1950), 1998-05, Vol.160 (9), p.4175-4181

1998

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Sultam Hydroxamates as Novel Matrix Metalloproteinase Inhibitors

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.2981-2983

2004

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Long-Term Depression in the Adult Hippocampus In Vivo Involves Activation of Extracellular Signal-Regulated Kinase and Phosphorylation of Elk-1

The Journal of neuroscience, 2002-03, Vol.22 (6), p.2054-2062

2002

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Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors

Bioorganic & medicinal chemistry, 2008, Vol.18 (1), p.241-246

2008

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COX-3: in the wrong frame in mind

Immunology letters, 2003-03, Vol.86 (1), p.121-121

2003

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A High-Throughput Fluorescent Polarization Assay for Nuclear Receptor Binding Utilizing Crude Receptor Extract

Analytical biochemistry, 2002-01, Vol.300 (1), p.15-21

2002

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α,β-Cyclic-β-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1288-1292

2008

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Synthesis and structure–activity relationship of a novel, achiral series of TNF-α converting enzyme inhibitors

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (10), p.2699-2704

2006

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Design, Synthesis, and Evaluation of Benzothiadiazepine Hydroxamates as Selective Tumor Necrosis Factor-α Converting Enzyme Inhibitors

Journal of medicinal chemistry, 2003-05, Vol.46 (10), p.1811-1823

2003

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Dependence of Dbl and Dbs Transformation on MEK and NF-κB Activation

Molecular and Cellular Biology, 1999-11, Vol.19 (11), p.7759-7770

1999

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The map kinase ERK regulates renal activity of cyclin-dependent kinase 2 in experimental glomerulonephritis

Nephrology, dialysis, transplantation, 2007-12, Vol.22 (12), p.3431-3441

2007

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Role of the ERK pathway in psychostimulant-induced locomotor sensitization

Aggrecan Protects Cartilage Collagen from Proteolytic Cleavage

Cyclooxygenase-2 Differentially Directs Uterine Angiogenesis during Implantation in Mice

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II

Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis

Inhibition of MAP Kinase Kinase Prevents Cytokine and Prostaglandin E2 Production in Lipopolysaccharide-Stimulated Monocytes

Selective inhibition of eosinophil influx into the lung by small molecule CC chemokine receptor 3 antagonists in mouse models of allergic inflammation

Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe

In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis

The MAPK cascade is required for mammalian associative learning

Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

A necessity for MAP kinase activation in mammalian spatial learning

Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents

Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks T Cell Proliferation But Does Not Induce or Prevent Anergy

Sultam Hydroxamates as Novel Matrix Metalloproteinase Inhibitors

Long-Term Depression in the Adult Hippocampus In Vivo Involves Activation of Extracellular Signal-Regulated Kinase and Phosphorylation of Elk-1

Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors

COX-3: in the wrong frame in mind

A High-Throughput Fluorescent Polarization Assay for Nuclear Receptor Binding Utilizing Crude Receptor Extract

α,β-Cyclic-β-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Synthesis and structure–activity relationship of a novel, achiral series of TNF-α converting enzyme inhibitors

Design, Synthesis, and Evaluation of Benzothiadiazepine Hydroxamates as Selective Tumor Necrosis Factor-α Converting Enzyme Inhibitors

Dependence of Dbl and Dbs Transformation on MEK and NF-κB Activation

The map kinase ERK regulates renal activity of cyclin-dependent kinase 2 in experimental glomerulonephritis

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