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Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

Nature communications, 2021-03, Vol.12 (1), p.1426-1426, Article 1426

2021

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LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics

The Prostate, 2017-05, Vol.77 (6), p.654-671

2017

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Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

Nature communications, 2019-07, Vol.10 (1), p.2781-8, Article 2781

2019

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ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors

Cancer cell, 2015-06, Vol.27 (6), p.797-808

2015

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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis

Cancer discovery, 2014-11, Vol.4 (11), p.1310-1325

2014

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Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

PloS one, 2011-11, Vol.6 (11), p.e27970-e27970

2011

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Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth

Cancer research (Chicago, Ill.), 2008-06, Vol.68 (11), p.4447-4454

2008

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Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens

Nature biomedical engineering, 2017-07, Vol.1 (7), Article 0084

2017

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SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Clinical cancer research, 2015-10, Vol.21 (20), p.4698-4708

2015

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Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors

Clinical cancer research, 2015-03, Vol.21 (6), p.1273-1280

2015

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Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy

Nature communications, 2023-04, Vol.14 (1), p.2041-2041, Article 2041

2023

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Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer

Nature communications, 2021-07, Vol.12 (1), p.4217-4217, Article 4217

2021

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Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

Clinical cancer research, 2019-01, Vol.25 (1), p.426-439

2019

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Human Cancers Express a Mutator Phenotype

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (48), p.18238-18242

2006

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Multi-resolution open-top light-sheet microscopy to enable efficient 3D pathology workflows

Biomedical optics express, 2020-11, Vol.11 (11), p.6605-6619

2020

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causal role for ERG in neoplastic transformation of prostate epithelium

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (6), p.2105-2110

2008

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Quality control in molecular immunohistochemistry

Histochemistry and cell biology, 2008-09, Vol.130 (3), p.473-480

True, Lawrence D.

2008

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Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression : Therapeutic implications for castration-resistant prostate cancer

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (10), p.5033-5041

2007

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Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents

Clinical cancer research, 2010-03, Vol.16 (6), p.1745-1755

2010

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Development and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis

Human pathology, 2022-04, Vol.122, p.84-91

2022

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High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker

Scientific reports, 2024-01, Vol.14 (1), p.486-486, Article 486

2024

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Bone metastasis in prostate cancer: Recurring mitochondrial DNA mutation reveals selective pressure exerted by the bone microenvironment

Bone (New York, N.Y.), 2015-09, Vol.78, p.81-86

2015

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Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations

Cell reports (Cambridge), 2023-08, Vol.42 (8), p.112840-112840, Article 112840

2023

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Targeted Androgen Pathway Suppression in Localized Prostate Cancer: A Pilot Study

Journal of clinical oncology, 2014-01, Vol.32 (3), p.229-237

2014

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Locus-specific gene repositioning in prostate cancer

Molecular biology of the cell, 2016-01, Vol.27 (2), p.236-246

2016

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Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors

The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis

Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth

Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors

Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy

Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer

Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

Human Cancers Express a Mutator Phenotype

Multi-resolution open-top light-sheet microscopy to enable efficient 3D pathology workflows

causal role for ERG in neoplastic transformation of prostate epithelium

Quality control in molecular immunohistochemistry

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression : Therapeutic implications for castration-resistant prostate cancer

Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents

Development and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis

High expression of Trop2 is associated with aggressive localized prostate cancer and is a candidate urinary biomarker

Bone metastasis in prostate cancer: Recurring mitochondrial DNA mutation reveals selective pressure exerted by the bone microenvironment

Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations

Targeted Androgen Pathway Suppression in Localized Prostate Cancer: A Pilot Study

Locus-specific gene repositioning in prostate cancer

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