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An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma

Mucosal immunology, 2014-09, Vol.7 (5), p.1175-1185

2014

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Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation

Clinical and experimental allergy, 2012-05, Vol.42 (5), p.760-768

2012

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The complex relationship between inflammation and lung function in severe asthma

Mucosal immunology, 2014-09, Vol.7 (5), p.1186-1198

2014

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IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

Clinical and experimental allergy, 2008-06, Vol.38 (6), p.936-946

2008

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Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

American journal of respiratory and critical care medicine, 1999-09, Vol.160 (3), p.1001-1008

1999

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Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition

Clinical and experimental allergy, 2002-11, Vol.32 (11), p.1558-1565

2002

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Persistent wheezing in very young children is associated with lower respiratory inflammation

American journal of respiratory and critical care medicine, 2001-05, Vol.163 (6), p.1338-1343

2001

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Effect of 5-lipoxygenase inhibition on bronchoconstriction and airway inflammation in nocturnal asthma

American journal of respiratory and critical care medicine, 1995-09, Vol.152 (3), p.897-905

1995

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Increased TGF- beta 2 in severe asthma with eosinophilia

Journal of Allergy and Clinical Immunology, 2005-01, Vol.115 (1), p.110-117

2005

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Theophylline: Potential antiinflammatory effects in nocturnal asthma

Journal of allergy and clinical immunology, 1996-06, Vol.97 (6), p.1242-1246

1996

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Peripheral blood and airway tissue expression of transforming growth factor β by neutrophils in asthmatic subjects and normal control subjects

Journal of allergy and clinical immunology, 2000-12, Vol.106 (6), p.1115-1123

2000

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Interleukin-13-induced MUC5AC Is Regulated by 15-Lipoxygenase 1 Pathway in Human Bronchial Epithelial Cells

American journal of respiratory and critical care medicine, 2009-05, Vol.179 (9), p.782-790

2009

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IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

Clinical and experimental allergy, 2008-08, Vol.38 (8), p.1409-1409

2008

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A40 EPITHELIAL REGULATION OF INFLAMMATION: An Exploratory Pathway Analysis Of Wound-Induced Gene Responses In Healthy And Asthmatic Human Airway Epithelial Cells (haec)

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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D33 AIRWAY EPITHELIA ACTIVATION AND RESPONSES TO TREATMENT: Il-13 Inhibits Wound Repair Of Asthmatic Bronchial Epithelial Cells

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids

Journal of allergy and clinical immunology, 2003-12, Vol.112 (6), p.1064-1071

2003

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D44 FIRST LINE OF DEFENSE: AIRWAY RESPONSE TO INFECTIONS AND IRRITANTS: Asthmatic Airway Epithelial Cells Exhibit Delayed Wound Closure And Cell Proliferation, Effects Enhanced By Il-13

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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D21 ASTHMA TREATMENT: GLUCOCORTICOIDS, BIOLOGICALS AND BEYOND:The Effect Of The 15-Lipoxygenase 1 (15lo1) Inhibitor Blx2477 On Il-13-Induced Periostin Mrna Expression In Human Airway Epithelial Cells (haecs)

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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C22 AIRWAY EPITHELIUM: MOLECULAR REGULATION OF INFLAMMATION: Phosphatidylethanolamine-Binding Protein 1 Modulates 15-Lipoxygenase 1 Pathway In Human Airway Epithelial Cells

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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B93 GENETIC SIGNATURES OF ASTHMA: KEY TO ENDOTYPES?: Circadian Rhythm And Clock Gene Expression Are Altered In Asthmatic Epithelium And Bronchoalveolar Lavage (bal) Cells

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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Single oral dose of prednisone decreases leukotriene B4 production by alveolar macrophages from patients with nocturnal asthma but not control subjects : relationship to changes in cellular influx and FEV1

Journal of allergy and clinical immunology, 1994-11, Vol.94 (5), p.870-881

1994

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Peritoneal lavage fluid alters patterns of eicosanoid production in murine bone marrow-derived and peritoneal macrophages : dependency on inflammatory state of the peritoneum

Inflammation, 1993-12, Vol.17 (6), p.743-756

1993

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TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts

The Journal of immunology (1950), 2002-10, Vol.169 (8), p.4613-4619

2002

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Sputum Mast Cell Markers Reflect Invasive Measures and Represent a Noninvasive Biologic Marker of Asthma Control and Severity

Journal of allergy and clinical immunology, 2011-02, Vol.127 (2), p.AB131-AB131

2011

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The Relationship of Induced-Sputum Inflammatory Cells to BAL and Biopsy

Chest, 2003-03, Vol.123 (3), p.371S-372S

2003

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An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma

Nitric oxide and related enzymes in asthma: relation to severity, enzyme function and inflammation

The complex relationship between inflammation and lung function in severe asthma

IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition

Persistent wheezing in very young children is associated with lower respiratory inflammation

Effect of 5-lipoxygenase inhibition on bronchoconstriction and airway inflammation in nocturnal asthma

Increased TGF- beta 2 in severe asthma with eosinophilia

Theophylline: Potential antiinflammatory effects in nocturnal asthma

Peripheral blood and airway tissue expression of transforming growth factor β by neutrophils in asthmatic subjects and normal control subjects

Interleukin-13-induced MUC5AC Is Regulated by 15-Lipoxygenase 1 Pathway in Human Bronchial Epithelial Cells

IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

A40 EPITHELIAL REGULATION OF INFLAMMATION: An Exploratory Pathway Analysis Of Wound-Induced Gene Responses In Healthy And Asthmatic Human Airway Epithelial Cells (haec)

D33 AIRWAY EPITHELIA ACTIVATION AND RESPONSES TO TREATMENT: Il-13 Inhibits Wound Repair Of Asthmatic Bronchial Epithelial Cells

Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids

D44 FIRST LINE OF DEFENSE: AIRWAY RESPONSE TO INFECTIONS AND IRRITANTS: Asthmatic Airway Epithelial Cells Exhibit Delayed Wound Closure And Cell Proliferation, Effects Enhanced By Il-13

D21 ASTHMA TREATMENT: GLUCOCORTICOIDS, BIOLOGICALS AND BEYOND:The Effect Of The 15-Lipoxygenase 1 (15lo1) Inhibitor Blx2477 On Il-13-Induced Periostin Mrna Expression In Human Airway Epithelial Cells (haecs)

C22 AIRWAY EPITHELIUM: MOLECULAR REGULATION OF INFLAMMATION: Phosphatidylethanolamine-Binding Protein 1 Modulates 15-Lipoxygenase 1 Pathway In Human Airway Epithelial Cells

B93 GENETIC SIGNATURES OF ASTHMA: KEY TO ENDOTYPES?: Circadian Rhythm And Clock Gene Expression Are Altered In Asthmatic Epithelium And Bronchoalveolar Lavage (bal) Cells

Single oral dose of prednisone decreases leukotriene B4 production by alveolar macrophages from patients with nocturnal asthma but not control subjects : relationship to changes in cellular influx and FEV1

Peritoneal lavage fluid alters patterns of eicosanoid production in murine bone marrow-derived and peritoneal macrophages : dependency on inflammatory state of the peritoneum

TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts

Sputum Mast Cell Markers Reflect Invasive Measures and Represent a Noninvasive Biologic Marker of Asthma Control and Severity

The Relationship of Induced-Sputum Inflammatory Cells to BAL and Biopsy

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