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The complement system as a potential therapeutic target in rheumatic disease

Nature reviews. Rheumatology, 2017-09, Vol.13 (9), p.538-547

2017

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Closing the serological gap: promising novel biomarkers for the early diagnosis of rheumatoid arthritis

Autoimmunity reviews, 2012-12, Vol.12 (2), p.318-322

2012

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Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis

Nature reviews. Rheumatology, 2017-06, Vol.13 (6), p.331-339

2017

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Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

Frontiers in immunology, 2018-11, Vol.9 (NOV), p.2664-2664

2018

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Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

Annals of the rheumatic diseases, 2015-01, Vol.74 (1), p.234-241

2015

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Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

Annals of the rheumatic diseases, 2014-04, Vol.73 (4), p.780-783

2014

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Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis

Annals of the rheumatic diseases, 2016-03, Vol.75 (3), p.578-585

2016

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Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.17372-17377

2011

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Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains

Nature communications, 2023-07, Vol.14 (1), p.4027-4027, Article 4027

2023

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Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients

Science translational medicine, 2015-06, Vol.7 (290), p.290ra87

2015

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The influence of ACPA status and characteristics on the course of RA

Nature reviews. Rheumatology, 2012-03, Vol.8 (3), p.144-152

2012

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Circulating C1q levels in health and disease, more than just a biomarker

Molecular immunology, 2021-12, Vol.140, p.206-216

2021

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PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (33), p.1-e2208144119

2022

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Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

Annals of the rheumatic diseases, 2019-07, Vol.78 (7), p.908-916

2019

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Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

Autoimmunity reviews, 2014-03, Vol.13 (3), p.225-230

2014

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Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

Arthritis research & therapy, 2016-02, Vol.18 (43), p.43-43, Article 43

2016

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Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

Arthritis research & therapy, 2012-08, Vol.14 (4), p.R185-R185, Article R185

2012

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Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

PloS one, 2014-07, Vol.9 (7), p.e102163-e102163

2014

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Complement activation and regulation in rheumatic disease

Seminars in immunology, 2019-10, Vol.45, p.101339-101339, Article 101339

2019

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C1q, antibodies and anti-C1q autoantibodies

Molecular immunology, 2015-11, Vol.68 (1), p.6-13

2015

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Geo-epidemiology of autoantibodies in rheumatoid arthritis: comparison between four ethnically diverse populations

Arthritis research & therapy, 2023-03, Vol.25 (1), p.37-37, Article 37

2023

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Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals

Arthritis & rheumatology (Hoboken, N.J.), 2018-11, Vol.70 (11), p.1721-1731

2018

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C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack

The Journal of biological chemistry, 2007-09, Vol.282 (39), p.28540-28548

2007

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Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein

Proceedings of the National Academy of Sciences - PNAS, 2024-09, Vol.121 (37), p.e2404542121

2024

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DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation

Journal of the American Chemical Society, 2024-05, Vol.146 (19), p.13455-13466

2024

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The complement system as a potential therapeutic target in rheumatic disease

Closing the serological gap: promising novel biomarkers for the early diagnosis of rheumatoid arthritis

Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients

The influence of ACPA status and characteristics on the course of RA

Circulating C1q levels in health and disease, more than just a biomarker

PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation

Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

Complement activation and regulation in rheumatic disease

C1q, antibodies and anti-C1q autoantibodies

Geo-epidemiology of autoantibodies in rheumatoid arthritis: comparison between four ethnically diverse populations

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals

C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack

Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein

DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation

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