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Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Cancer discovery, 2017-05, Vol.7 (5), p.462-477

2017

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Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram

Stem cells (Dayton, Ohio), 2015-04, Vol.33 (4), p.1042-1046

2015

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Rare histologic transformation of a CTNNB1 (β-catenin) mutated prostate cancer with aggressive clinical course

Diagnostic pathology, 2024-06, Vol.19 (1), p.83-10, Article 83

2024

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YB-1 Bridges Neural Stem Cells and Brain Tumor―Initiating Cells via Its Roles in Differentiation and Cell Growth

Cancer research (Chicago, Ill.), 2011-08, Vol.71 (16), p.5569-5578

2011

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Beyond PI3Ks: targeting phosphoinositide kinases in disease

Nature reviews. Drug discovery, 2023-05, Vol.22 (5), p.357-386

2023

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Prostate Power Play: Does Pik3ca Accelerate Pten -Deficient Cancer Progression?

Cancer discovery, 2018-06, Vol.8 (6), p.682-685

2018

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Loss of PI5P4Kα slows the progression of a Pten mutant basal cell model of prostate cancer

Molecular cancer research, 2024-10

2024

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PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay

Developmental cell, 2021-06, Vol.56 (11), p.1661-1676.e10

2021

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Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

The lancet oncology, 2013-11, Vol.14 (12), p.1200-1207

2013

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Minor intron splicing is critical for survival of lethal prostate cancer

Molecular cell, 2023-06, Vol.83 (12), p.1983-2002.e11

2023

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Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

Clinical cancer research, 2022-01, Vol.28 (1), p.116-128

2022

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Histologic Correlates of Molecular Group 4 Pediatric Medulloblastoma: A Retrospective Canadian Review

Pediatric and developmental pathology, 2021-08, Vol.24 (4), p.309-317

2021

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Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review

Child's nervous system, 2023-08, Vol.39 (8), p.2095-2104

2023

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Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide

Oncotarget, 2012-10, Vol.3 (10), p.1112-1123

2012

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Abstract A078: Towards understanding noncanonical phosphatidylinositol kinases in the maintenance of prostate metabolism

Cancer research (Chicago, Ill.), 2018-08, Vol.78 (16_Supplement), p.A078-A078

2018

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Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children

Cancer research (Chicago, Ill.), 2013-11, Vol.73 (22), p.6734-6744

2013

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PATH-03. Clinically Tractable Outcome Prediction of Group 3/4 Medulloblastoma Based on TPD52 Immunohistochemistry: a Multicohort Study

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i158-i158

2022

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EMBR-21. CLINICALLY TRACTABLE OUTCOME PREDICTION OF GROUP 3/4 MEDULLOBLASTOMA BASED ON TPD52 IMMUNOHISTOCHEMISTRY: A MULTICOHORT STUDY

Neuro-oncology (Charlottesville, Va.), 2021-06, Vol.23 (Supplement_1), p.i10-i10

2021

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Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice

Stem cells (Dayton, Ohio), 2012-06, Vol.30 (6), p.1064-1075

2012

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Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma

Journal of clinical oncology, 2015-02, Vol.33 (6), p.e27-e31

2015

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FoxG1 Interacts with Bmi1 to Regulate Self‐Renewal and Tumorigenicity of Medulloblastoma Stem Cells

Stem cells (Dayton, Ohio), 2013-07, Vol.31 (7), p.1266-1277

2013

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PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition

Science advances, 2023-02, Vol.9 (5), p.eade8641

2023

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Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma

Pediatric blood & cancer, 2014-01, Vol.61 (1), p.107-115

2014

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Abstract 811: VAL083, a novel N7 alkylating agent, surpasses temozolomide activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.811-811

2012

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Effect of VAL-083, a novel N7 alkylating agent, on growth of temolozomide-resistant primary adult glioblastoma multiforme (GBM) cells providing a new potential treatment option for GBM

Journal of clinical oncology, 2012-05, Vol.30 (15_suppl), p.e13123-e13123

2012

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Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram

Rare histologic transformation of a CTNNB1 (β-catenin) mutated prostate cancer with aggressive clinical course

YB-1 Bridges Neural Stem Cells and Brain Tumor―Initiating Cells via Its Roles in Differentiation and Cell Growth

Beyond PI3Ks: targeting phosphoinositide kinases in disease

Prostate Power Play: Does Pik3ca Accelerate Pten -Deficient Cancer Progression?

Loss of PI5P4Kα slows the progression of a Pten mutant basal cell model of prostate cancer

PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay

Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis

Minor intron splicing is critical for survival of lethal prostate cancer

Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

Histologic Correlates of Molecular Group 4 Pediatric Medulloblastoma: A Retrospective Canadian Review

Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review

Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide

Abstract A078: Towards understanding noncanonical phosphatidylinositol kinases in the maintenance of prostate metabolism

Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children

PATH-03. Clinically Tractable Outcome Prediction of Group 3/4 Medulloblastoma Based on TPD52 Immunohistochemistry: a Multicohort Study

EMBR-21. CLINICALLY TRACTABLE OUTCOME PREDICTION OF GROUP 3/4 MEDULLOBLASTOMA BASED ON TPD52 IMMUNOHISTOCHEMISTRY: A MULTICOHORT STUDY

Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice

Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma

FoxG1 Interacts with Bmi1 to Regulate Self‐Renewal and Tumorigenicity of Medulloblastoma Stem Cells

PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition

Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma

Abstract 811: VAL083, a novel N7 alkylating agent, surpasses temozolomide activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme

Effect of VAL-083, a novel N7 alkylating agent, on growth of temolozomide-resistant primary adult glioblastoma multiforme (GBM) cells providing a new potential treatment option for GBM

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