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A Low-Glycemic, Mediterranean Diet and Lifestyle Modification Program with Targeted Nutraceuticals Reduces Body Weight, Improves Cardiometabolic Variables and Longevity Biomarkers in Overweight Subjects: A 13-Week Observational Trial

Journal of medicinal food, 2019-05, Vol.22 (5), p.479-489

2019

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META060 protects against diet-induced obesity and insulin resistance in a high-fat–diet fed mouse

Nutrition (Burbank, Los Angeles County, Calif.), 2013, Vol.29 (1), p.276-283

2013

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Antidiabetic screening of commercial botanical products in 3T3-L1 adipocytes and db/db mice

Journal of medicinal food, 2010-06, Vol.13 (3), p.535-547

2010

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Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial

Nutrition & metabolism, 2008-11, Vol.5 (1), p.29-29, Article 29

2008

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Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation

Journal of inflammation (London, England), 2009-08, Vol.6 (1), p.26-26

2009

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Subjects with elevated LDL cholesterol and metabolic syndrome benefit from supplementation with soy protein, phytosterols, hops rho iso-alpha acids, and Acacia nilotica proanthocyanidins

Journal of clinical lipidology, 2010-01, Vol.4 (1), p.59-68

2010

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META060 attenuates TNF-α-activated inflammation, endothelial–monocyte interactions, and matrix metalloproteinase-9 expression, and inhibits NF-κB and AP-1 in THP-1 monocytes

Atherosclerosis, 2012-07, Vol.223 (1), p.130-136

2012

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Optimized mixture of hops rho iso-alpha acids-rich extract and acacia proanthocyanidins-rich extract reduces insulin resistance in 3T3-L1 adipocytes and improves glucose and insulin control in db/db mice

Nutrition Research and Practice, 2012, 6(5), , pp.405-413

2012

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A 13-week low glycemic load diet and lifestyle modification program combining low glycemic load protein shakes and targeted nutraceuticals improved weight loss and cardio-metabolic risk factors

Canadian journal of physiology and pharmacology, 2017-12, Vol.95 (12), p.1414-1425

2017

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Synergistic in vitro antioxidant activity and observational clinical trial of F105, a phytochemical formulation including Citrus bergamia, in subjects with moderate cardiometabolic risk factors

Canadian journal of physiology and pharmacology, 2016-12, Vol.94 (12), p.1257-1266

2016

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Hop rho iso-alpha acids, berberine, vitamin D₃ and vitamin K₁ favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial

Journal of bone and mineral metabolism, 2010-05, Vol.28 (3), p.342-350

2010

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Hop and Acacia Phytochemicals Decreased Lipotoxicity in 3T3-L1 Adipocytes, db/db Mice, and Individuals with Metabolic Syndrome

Journal of Nutrition and Metabolism, 2010-01, Vol.2010 (2010), p.1-11

2010

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Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops

Phytochemistry (Oxford), 2008-05, Vol.69 (7), p.1534-1547

2008

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Isolation of bitter acids from hops (Humulus lupulus L.) using countercurrent chromatography

Journal of separation science, 2012-05, Vol.35 (9), p.1183-1189

2012

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Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D3 , and vitamin K1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome

Nutrition research (New York, N.Y.), 2011-05, Vol.31 (5), p.347-355

2011

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Countercurrent purification of the tetrahydro iso-α acids derived from Humulus lupulus L

Journal of separation science, 2010-09, Vol.33 (17-18), p.2828-2832

2010

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A program consisting of a phytonutrient-rich medical food and an elimination diet ameliorated fibromyalgia symptoms and promoted toxic-element detoxification in a pilot trial

Alternative therapies in health and medicine, 2011-03, Vol.17 (2), p.36

2011

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A science-based, clinically tested dietary approach for the metabolic syndrome

Metabolic syndrome and related disorders, 2009-06, Vol.7 (3), p.187-192

2009

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META060 inhibits osteoclastogenesis and matrix metalloproteinases in vitro and reduces bone and cartilage degradation in a mouse model of rheumatoid arthritis

Arthritis and rheumatism, 2010-06, Vol.62 (6), p.1683-1692

2010

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Effect of META060, a substituted 1,3‐cyclopentadione compound derived from hops, in the management of obesity

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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META060 activates omega‐3 fatty acid receptor GPR120, reduces weight gain, and increases insulin sensitivity in high‐fat diet fed mice

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D 3, and vitamin K 1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome

Nutrition research (New York, N.Y.), 2011-05, Vol.31 (5), p.347-355

2011

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META060 from hops reduces weight gain, increases weight loss, improves fasting glucose and insulin sensitivity in high‐fat fed mice

The FASEB journal, 2010-04, Vol.24 (S1), p.105.8-105.8

2010

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A medical food and phytonutrient supplement improve cardiovascular disease risk factors in subjects with metabolic syndrome and elevated LDL

The FASEB journal, 2010-04, Vol.24 (S1), p.739.1-739.1

2010

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Reduced weight gain and improved insulin sensitivity in high‐fat fed mice by treatment with a mixture of a reduced isohumulones from hops and an extract from acacia

The FASEB journal, 2010-04, Vol.24 (S1), p.335.4-335.4

2010

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A Low-Glycemic, Mediterranean Diet and Lifestyle Modification Program with Targeted Nutraceuticals Reduces Body Weight, Improves Cardiometabolic Variables and Longevity Biomarkers in Overweight Subjects: A 13-Week Observational Trial

META060 protects against diet-induced obesity and insulin resistance in a high-fat–diet fed mouse

Antidiabetic screening of commercial botanical products in 3T3-L1 adipocytes and db/db mice

Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial

Rho iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation

Subjects with elevated LDL cholesterol and metabolic syndrome benefit from supplementation with soy protein, phytosterols, hops rho iso-alpha acids, and Acacia nilotica proanthocyanidins

META060 attenuates TNF-α-activated inflammation, endothelial–monocyte interactions, and matrix metalloproteinase-9 expression, and inhibits NF-κB and AP-1 in THP-1 monocytes

Optimized mixture of hops rho iso-alpha acids-rich extract and acacia proanthocyanidins-rich extract reduces insulin resistance in 3T3-L1 adipocytes and improves glucose and insulin control in db/db mice

A 13-week low glycemic load diet and lifestyle modification program combining low glycemic load protein shakes and targeted nutraceuticals improved weight loss and cardio-metabolic risk factors

Synergistic in vitro antioxidant activity and observational clinical trial of F105, a phytochemical formulation including Citrus bergamia, in subjects with moderate cardiometabolic risk factors

Hop rho iso-alpha acids, berberine, vitamin D₃ and vitamin K₁ favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial

Hop and Acacia Phytochemicals Decreased Lipotoxicity in 3T3-L1 Adipocytes, db/db Mice, and Individuals with Metabolic Syndrome

Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops

Isolation of bitter acids from hops (Humulus lupulus L.) using countercurrent chromatography

Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D3 , and vitamin K1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome

Countercurrent purification of the tetrahydro iso-α acids derived from Humulus lupulus L

A program consisting of a phytonutrient-rich medical food and an elimination diet ameliorated fibromyalgia symptoms and promoted toxic-element detoxification in a pilot trial

A science-based, clinically tested dietary approach for the metabolic syndrome

META060 inhibits osteoclastogenesis and matrix metalloproteinases in vitro and reduces bone and cartilage degradation in a mouse model of rheumatoid arthritis

Effect of META060, a substituted 1,3‐cyclopentadione compound derived from hops, in the management of obesity

META060 activates omega‐3 fatty acid receptor GPR120, reduces weight gain, and increases insulin sensitivity in high‐fat diet fed mice

Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D 3, and vitamin K 1 produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome

META060 from hops reduces weight gain, increases weight loss, improves fasting glucose and insulin sensitivity in high‐fat fed mice

A medical food and phytonutrient supplement improve cardiovascular disease risk factors in subjects with metabolic syndrome and elevated LDL

Reduced weight gain and improved insulin sensitivity in high‐fat fed mice by treatment with a mixture of a reduced isohumulones from hops and an extract from acacia

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