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Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

Cell reports (Cambridge), 2017-03, Vol.18 (11), p.2547-2556

2017

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STAT3 Signaling Is Required for Optimal Regression of Large Established Tumors in Mice Treated with Anti-OX40 and TGFβ Receptor Blockade

Cancer immunology research, 2015-05, Vol.3 (5), p.526-535

2015

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Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

Nature medicine, 2017-01, Vol.23 (1), p.120-127

2017

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Abstract LB-226: Depletion of kynurenine using an engineered therapeutic enzyme potently inhibits cancer immune checkpoints both as a monotherapy and in combination with anti-PD-1

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.LB-226-LB-226

2015

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Abstract 5570: A novel approach to targeting the IDO/TDO pathway through degradation of the immunosuppressive metabolite kynurenine

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5570-5570

2017

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Systemic depletion of L-cystinase increases reactive oxygen species and suppresses tumor growth

Nature medicine, 2017-01, Vol.23 (1), p.120

2017

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Systemic depletion of serum l-Cyst(e)ine with an engineered human enzyme induces production of reactive oxygen species and suppresses tumor growth in mice

Nature medicine, 2016-11, Vol.23 (1), p.120-127

2016

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Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

Nature biotechnology, 2018-09, Vol.36 (8), p.758-764

2018

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Neurocognitive functioning in long-term survivors of pediatric hematopoietic cell transplantation

Bone marrow transplantation (Basingstoke), 2021-04, Vol.56 (4), p.873-882

2021

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Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

Nature communications, 2022-06, Vol.13 (1), p.3151-8, Article 3151

2022

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Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

Diabetes care, 2015-02, Vol.38 (2), p.329-332

2015

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A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset

BMC genomics, 2022-09, Vol.23 (1), p.661-661, Article 661

2022

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Immune Correlates of Protection from Filovirus Efficacy Studies in Non-Human Primates

Vaccines (Basel), 2022-08, Vol.10 (8), p.1338

2022

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Psychosocial outcomes of parents in pediatric haploidentical transplant: parental hematopoietic cell donation as a double-edged sword

Bone marrow transplantation (Basingstoke), 2022-03, Vol.57 (3), p.377-383

2022

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“Giving the gift of life twice”: Understanding the lived experiences of parent donors and nondonors in pediatric haploidentical hematopoietic cell transplantation

Pediatric blood & cancer, 2022-02, Vol.69 (2), p.e29480-n/a

2022

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The Force Awakens: Illuminating the Role of Kynurenine in Cancer Progression and Treatment

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.240-240.16

2020

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The Force Awakens: Illuminating the role of kynurenine in cancer progression and treatment

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.177-177.3

2018

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Reversal of IDO-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

Nature biotechnology, 2018-07, Vol.36 (8), p.758-764

2018

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Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Scientific reports, 2016-06, Vol.6 (1), p.27887, Article 27887

2016

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Combining anti-OX40 with an inhibitor of TGF-β signaling overcomes the immunosuppressive environment in established tumors (P2026)

The Journal of immunology (1950), 2013-05, Vol.190 (1_Supplement), p.132-132.3

2013

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Corrigendum: A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study

Scientific reports, 2017-05, Vol.7, p.39723-39723

2017

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STAT3 signaling is required for anti-OX40/TGF-β receptor blockade-mediated regression of large established tumors

Journal for immunotherapy of cancer, 2013-11, Vol.1 (S1), p.P68-P68, Article P68

2013

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Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

STAT3 Signaling Is Required for Optimal Regression of Large Established Tumors in Mice Treated with Anti-OX40 and TGFβ Receptor Blockade

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions

Abstract LB-226: Depletion of kynurenine using an engineered therapeutic enzyme potently inhibits cancer immune checkpoints both as a monotherapy and in combination with anti-PD-1

Abstract 5570: A novel approach to targeting the IDO/TDO pathway through degradation of the immunosuppressive metabolite kynurenine

Systemic depletion of L-cystinase increases reactive oxygen species and suppresses tumor growth

Systemic depletion of serum l-Cyst(e)ine with an engineered human enzyme induces production of reactive oxygen species and suppresses tumor growth in mice

Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease

Neurocognitive functioning in long-term survivors of pediatric hematopoietic cell transplantation

Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

A robust and transformation-free joint model with matching and regularization for metagenomic trajectory and disease onset

Immune Correlates of Protection from Filovirus Efficacy Studies in Non-Human Primates

Psychosocial outcomes of parents in pediatric haploidentical transplant: parental hematopoietic cell donation as a double-edged sword

“Giving the gift of life twice”: Understanding the lived experiences of parent donors and nondonors in pediatric haploidentical hematopoietic cell transplantation

The Force Awakens: Illuminating the Role of Kynurenine in Cancer Progression and Treatment

The Force Awakens: Illuminating the role of kynurenine in cancer progression and treatment

Reversal of IDO-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Combining anti-OX40 with an inhibitor of TGF-β signaling overcomes the immunosuppressive environment in established tumors (P2026)

Corrigendum: A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study

STAT3 signaling is required for anti-OX40/TGF-β receptor blockade-mediated regression of large established tumors

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