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Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1618, p.175

Trim, Paul J

2017

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Butanolysis Derivatization: Improved Sensitivity in LC-MS/MS Quantitation of Heparan Sulfate in Urine from Mucopolysaccharidosis Patients

Analytical chemistry (Washington), 2015-09, Vol.87 (18), p.9243-9250

2015

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The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD

Scientific reports, 2021-02, Vol.11 (1), p.4106-4106, Article 4106

2021

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Synthesis and mass spectrometric analysis of disaccharides from methanolysis of heparan sulfate

Organic & biomolecular chemistry, 2018-11, Vol.16 (45), p.8791-8803

2018

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Matrix-Assisted Laser Desorption/Ionization-Ion Mobility Separation-Mass Spectrometry Imaging of Vinblastine in Whole Body Tissue Sections

Analytical chemistry (Washington), 2008-11, Vol.80 (22), p.8628-8634

2008

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Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics

Cancers, 2022-03, Vol.14 (7), p.1702

2022

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A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA

Rapid communications in mass spectrometry, 2014-04, Vol.28 (8), p.933-938

2014

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Determination of the role of injection site on the efficacy of intra-CSF enzyme replacement therapy in MPS IIIA mice

Molecular genetics and metabolism, 2015-05, Vol.115 (1), p.33-40

2015

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AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.174-187

2020

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FAST-IT: Find A Simple Test — In TIA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass spectrometry, neuroimaging and machine learning—study protocol

BMJ open, 2022-04, Vol.12 (4), p.e045908-e045908

2022

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Is the eye a window to the brain in Sanfilippo syndrome?

Acta neuropathologica communications, 2020-11, Vol.8 (1), p.194-194, Article 194

2020

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Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer’s disease

IBRO neuroscience reports, 2022-06, Vol.12, p.131-141

2022

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Small molecule MALDI MS imaging: Current technologies and future challenges

Methods (San Diego, Calif.), 2016-07, Vol.104, p.127-141

2016

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Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse

Cells (Basel, Switzerland), 2021-04, Vol.10 (4), p.849

2021

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Equivalent Carbon Number and Interclass Retention Time Conversion Enhance Lipid Identification in Untargeted Clinical Lipidomics

Analytical chemistry (Washington), 2022-03, Vol.94 (8), p.3476-3484

2022

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Repetitive, non-invasive imaging of neurodegeneration, and prevention of it with gene replacement, in mice with Sanfilippo syndrome

Experimental neurology, 2024-01, Vol.371, p.114610-114610, Article 114610

2024

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Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition

Cancer research (Chicago, Ill.), 2021-10, Vol.81 (19), p.4981-4993

2021

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Modifying Dietary Protein Impacts mTOR Signaling and Brain Deposition of Amyloid β in a Knock-In Mouse Model of Alzheimer Disease

The Journal of nutrition, 2023-05, Vol.153 (5), p.1407-1419

2023

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Spatial MS multiomics on clinical prostate cancer tissues

Analytical and bioanalytical chemistry, 2024-03, Vol.416 (7), p.1745-1757

2024

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Filipin complex‐reactive brain lesions: A cautionary tale

Neuropathology and applied neurobiology, 2024-02, Vol.50 (1), p.e12950-n/a

2024

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Retro Diels–Alder Fragmentation of Fulvene–Maleimide Bioconjugates for Mass Spectrometric Detection of Biomolecules

Analytical chemistry (Washington), 2021-09, Vol.93 (36), p.12204-12212

2021

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Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids

Analytical and bioanalytical chemistry, 2021-04, Vol.413 (10), p.2695-2708

2021

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Drosophila melanogaster models of MPS IIIC (Hgsnat‐deficiency) highlight the role of glia in disease presentation

Journal of inherited metabolic disease, 2024-03, Vol.47 (2), p.340-354

2024

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Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis

International journal of cancer, 2018-05, Vol.142 (9), p.1865-1877

2018

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Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

Cellular and molecular life sciences : CMLS, 2021-01, Vol.78 (1), p.249-270

2021

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Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging

Butanolysis Derivatization: Improved Sensitivity in LC-MS/MS Quantitation of Heparan Sulfate in Urine from Mucopolysaccharidosis Patients

The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD

Synthesis and mass spectrometric analysis of disaccharides from methanolysis of heparan sulfate

Matrix-Assisted Laser Desorption/Ionization-Ion Mobility Separation-Mass Spectrometry Imaging of Vinblastine in Whole Body Tissue Sections

Unravelling Prostate Cancer Heterogeneity Using Spatial Approaches to Lipidomics and Transcriptomics

A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA

Determination of the role of injection site on the efficacy of intra-CSF enzyme replacement therapy in MPS IIIA mice

AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains

FAST-IT: Find A Simple Test — In TIA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass spectrometry, neuroimaging and machine learning—study protocol

Is the eye a window to the brain in Sanfilippo syndrome?

Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer’s disease

Small molecule MALDI MS imaging: Current technologies and future challenges

Increased Alveolar Heparan Sulphate and Reduced Pulmonary Surfactant Amount and Function in the Mucopolysaccharidosis IIIA Mouse

Equivalent Carbon Number and Interclass Retention Time Conversion Enhance Lipid Identification in Untargeted Clinical Lipidomics

Repetitive, non-invasive imaging of neurodegeneration, and prevention of it with gene replacement, in mice with Sanfilippo syndrome

Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition

Modifying Dietary Protein Impacts mTOR Signaling and Brain Deposition of Amyloid β in a Knock-In Mouse Model of Alzheimer Disease

Spatial MS multiomics on clinical prostate cancer tissues

Filipin complex‐reactive brain lesions: A cautionary tale

Retro Diels–Alder Fragmentation of Fulvene–Maleimide Bioconjugates for Mass Spectrometric Detection of Biomolecules

Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids

Drosophila melanogaster models of MPS IIIC (Hgsnat‐deficiency) highlight the role of glia in disease presentation

Eukaryotic elongation factor 2 kinase upregulates the expression of proteins implicated in cell migration and cancer cell metastasis

Reciprocal signaling between mTORC1 and MNK2 controls cell growth and oncogenesis

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