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Long polyglutamine tracts in the androgen receptor are associated with reduced trans-activation, impaired sperm production, and male infertility

The journal of clinical endocrinology and metabolism, 1997-11, Vol.82 (11), p.3777-3782

1997

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Molecular Studies of a Patient with Complete Androgen Insensitivity and a 47,XXY Karyotype

The Journal of pediatrics, 2009-09, Vol.155 (3), p.439-443

2009

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Kennedy's disease : Caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

Journal of neurochemistry, 1999, Vol.72 (1), p.185-195

1999

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Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity

Journal of molecular endocrinology, 2002-08, Vol.29 (1), p.41-60

2002

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Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription

Molecular and Cellular Biology, 1989-12, Vol.9 (12), p.5305-5314

1989

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Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuronopathies

Human molecular genetics, 1995-04, Vol.4 (4), p.523-527

1995

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Interactions between androgen and estrogen receptors and the effects on their transactivational properties

Molecular and cellular endocrinology, 2000-09, Vol.167 (1), p.139-150

2000

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Spinobulbar Muscular Atrophy: Polyglutamine-expanded Androgen Receptor Is Proteolytically Resistant in Vitro and Processed Abnormally in Transfected Cells

Human molecular genetics, 1998-03, Vol.7 (3), p.379-384

1998

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Somatic mosaicism and variable expressivity

Trends in genetics, 2001-02, Vol.17 (2), p.79-82

2001

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Discordant measures of androgen-binding kinetics in two mutant androgen receptors causing mild or partial androgen insensitivity, respectively

The journal of clinical endocrinology and metabolism, 1999-02, Vol.84 (2), p.805-810

1999

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Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy

Nature genetics, 1993-10, Vol.5 (2), p.184-188

1993

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Substitution of aspartic acid-686 by histidine or asparagine in the human androgen receptor leads to a functionally inactive protein with altered hormone-binding characteristics

Molecular endocrinology (Baltimore, Md.), 1991-10, Vol.5 (10), p.1562-1569

1991

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Replacement of arginine 773 by cysteine of histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes

American journal of human genetics, 1992-07, Vol.51 (1), p.143-155

1992

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Variable expressivity and mutation databases: The androgen receptor gene mutations database

Human mutation, 2001-05, Vol.17 (5), p.382-388

2001

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Tissue-specific activity of the pro-opiomelanocortin gene promoter

Molecular and Cellular Biology, 1987-11, Vol.7 (11), p.4058-4064

1987

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Cytochrome c oxidase subunit Vb interacts with human androgen receptor: A potential mechanism for neurotoxicity in spinobulbar muscular atrophy

Brain research bulletin, 2001-11, Vol.56 (3-4), p.285-297

2001

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Oligospermic infertility associated with an androgen receptor mutation that disrupts interdomain and coactivator (TIF2) interactions

The Journal of clinical investigation, 1999-06, Vol.103 (11), p.1517-1525

1999

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The human androgen receptor: Structure/function relationship in normal and pathological situations

Journal of steroid biochemistry and molecular biology, 1992-03, Vol.41 (3), p.361-368

1992

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The polymorphic CAG repeat of the androgen receptor gene: a potential role in breast cancer in women over 40

Breast cancer research and treatment, 2001-11, Vol.70 (2), p.109-116

2001

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Progress in Spinobulbar muscular atrophy research: insights into neuronal dysfunction caused by the polyglutamine-expanded androgen receptor

Neurotoxicity research, 2005, Vol.7 (3), p.219-230

2005

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Characterization of alternative amino acid substitutions at arginine 830 of the androgen receptor that cause complete androgen insensitivity in three families

Human molecular genetics, 1995-04, Vol.4 (4), p.515-521

1995

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Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

The Journal of biological chemistry, 1998-04, Vol.273 (15), p.9158-9167

1998

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Analysis of exon 1 mutations in the androgen receptor gene

Human mutation, 1999-01, Vol.14 (6), p.527-539

1999

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Increased T-type Ca2+ channel activity as a determinant of cellular toxicity in neuronal cell lines expressing polyglutamine-expanded human androgen receptors

Molecular and cellular biochemistry, 2000-01, Vol.203 (1-2), p.23-31

2000

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Substitution of arginine-839 by cysteine or histidine in the androgen receptor causes different receptor phenotypes in cultured cells and coordinate degrees of clinical androgen resistance

The Journal of clinical investigation, 1994-08, Vol.94 (2), p.546-554

1994

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Long polyglutamine tracts in the androgen receptor are associated with reduced trans-activation, impaired sperm production, and male infertility

Molecular Studies of a Patient with Complete Androgen Insensitivity and a 47,XXY Karyotype

Kennedy's disease : Caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity

Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription

Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuronopathies

Interactions between androgen and estrogen receptors and the effects on their transactivational properties

Spinobulbar Muscular Atrophy: Polyglutamine-expanded Androgen Receptor Is Proteolytically Resistant in Vitro and Processed Abnormally in Transfected Cells

Somatic mosaicism and variable expressivity

Discordant measures of androgen-binding kinetics in two mutant androgen receptors causing mild or partial androgen insensitivity, respectively

Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy

Substitution of aspartic acid-686 by histidine or asparagine in the human androgen receptor leads to a functionally inactive protein with altered hormone-binding characteristics

Replacement of arginine 773 by cysteine of histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes

Variable expressivity and mutation databases: The androgen receptor gene mutations database

Tissue-specific activity of the pro-opiomelanocortin gene promoter

Cytochrome c oxidase subunit Vb interacts with human androgen receptor: A potential mechanism for neurotoxicity in spinobulbar muscular atrophy

Oligospermic infertility associated with an androgen receptor mutation that disrupts interdomain and coactivator (TIF2) interactions

The human androgen receptor: Structure/function relationship in normal and pathological situations

The polymorphic CAG repeat of the androgen receptor gene: a potential role in breast cancer in women over 40

Progress in Spinobulbar muscular atrophy research: insights into neuronal dysfunction caused by the polyglutamine-expanded androgen receptor

Characterization of alternative amino acid substitutions at arginine 830 of the androgen receptor that cause complete androgen insensitivity in three families

Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

Analysis of exon 1 mutations in the androgen receptor gene

Increased T-type Ca2+ channel activity as a determinant of cellular toxicity in neuronal cell lines expressing polyglutamine-expanded human androgen receptors

Substitution of arginine-839 by cysteine or histidine in the androgen receptor causes different receptor phenotypes in cultured cells and coordinate degrees of clinical androgen resistance

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