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Liver X receptor biology and pharmacology: new pathways, challenges and opportunities

Trends in pharmacological sciences (Regular ed.), 2012-07, Vol.33 (7), p.394-404

2012

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Transcriptional and epigenetic control of adipocyte remodeling during obesity

Obesity (Silver Spring, Md.), 2021-12, Vol.29 (12), p.2013-2025

2021

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Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

Nature communications, 2019-04, Vol.10 (1), p.1684-1684, Article 1684

2019

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Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation

Biochimica et biophysica acta, 2011-08, Vol.1812 (8), p.909-918

2011

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The Nuclear Receptor-Co-repressor Complex in Control of Liver Metabolism and Disease

Frontiers in endocrinology (Lausanne), 2019-06, Vol.10, p.411-411

2019

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Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

Nature Medicine, 2016-07, Vol.22 (7), p.780-791

2016

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Antioxidants stimulate BACH1-dependent tumor angiogenesis

The Journal of clinical investigation, 2023-10, Vol.133 (20), p.1-12

2023

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New wrestling rules of anti-inflammatory transrepression by oxysterol receptor LXR revealed

Cell research, 2011-05, Vol.21 (5), p.711-714

Treuter, Eckardt

2011

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Mechanisms of Estrogen Action

Physiological reviews, 2001-10, Vol.81 (4), p.1535-1565

2001

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GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

Cell reports (Cambridge), 2018-09, Vol.24 (11), p.2957-2971.e6

2018

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An optimized 4C-seq protocol based on cistrome and epigenome data in the mouse RAW264.7 macrophage cell line

STAR protocols, 2022-06, Vol.3 (2), p.101338-101338, Article 101338

2022

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Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages

BMC genomics, 2012-01, Vol.13 (1), p.50-50, Article 50

2012

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Transcriptional corepression by SHP: molecular mechanisms and physiological consequences

Trends in endocrinology and metabolism, 2005-12, Vol.16 (10), p.478-488

2005

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Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses

Advanced science, 2024-05, Vol.11 (20), p.e2307201-n/a

2024

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Activation Functions 1 and 2 of Nuclear Receptors: Molecular Strategies for Transcriptional Activation

Molecular endocrinology (Baltimore, Md.), 2003-10, Vol.17 (10), p.1901-1909

2003

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Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP binding cassette subfamily G member 1

Molecular metabolism (Germany), 2020-12, Vol.42, p.101066-101066, Article 101066

2020

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Coordinated Recruitment of Histone Methyltransferase G9a and Other Chromatin-Modifying Enzymes in SHP-Mediated Regulation of Hepatic Bile Acid Metabolism

Molecular and Cellular Biology, 2007-02, Vol.27 (4), p.1407-1424

2007

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Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells

PloS one, 2012, Vol.7 (3), p.e32080

2012

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Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

Human molecular genetics, 2009-08, Vol.18 (15), p.2802-2812

2009

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Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (40), p.15665-15670

2007

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Structural Insights into Corepressor Recognition by Antagonist-bound Estrogen Receptors

The Journal of biological chemistry, 2007-04, Vol.282 (14), p.10449-10455

2007

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DAX-1 Functions as an LXXLL-containing Corepressor for Activated Estrogen Receptors

The Journal of biological chemistry, 2000-12, Vol.275 (51), p.39855-39859

2000

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E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis

Molecular and Cellular Biology, 2009-04, Vol.29 (8), p.2230-2242

2009

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Glucocorticoid Signaling Is Perturbed by the Atypical Orphan Receptor and Corepressor SHP

The Journal of biological chemistry, 2002-12, Vol.277 (51), p.49761-49766

2002

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A Regulatory Role for RIP140 in Nuclear Receptor Activation

Molecular endocrinology (Baltimore, Md.), 1998-06, Vol.12 (6), p.864-881

1998

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Liver X receptor biology and pharmacology: new pathways, challenges and opportunities

Transcriptional and epigenetic control of adipocyte remodeling during obesity

Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation

The Nuclear Receptor-Co-repressor Complex in Control of Liver Metabolism and Disease

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

Antioxidants stimulate BACH1-dependent tumor angiogenesis

New wrestling rules of anti-inflammatory transrepression by oxysterol receptor LXR revealed

Mechanisms of Estrogen Action

GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

An optimized 4C-seq protocol based on cistrome and epigenome data in the mouse RAW264.7 macrophage cell line

Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages

Transcriptional corepression by SHP: molecular mechanisms and physiological consequences

Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses

Activation Functions 1 and 2 of Nuclear Receptors: Molecular Strategies for Transcriptional Activation

Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP binding cassette subfamily G member 1

Coordinated Recruitment of Histone Methyltransferase G9a and Other Chromatin-Modifying Enzymes in SHP-Mediated Regulation of Hepatic Bile Acid Metabolism

Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells

Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia

Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis

Structural Insights into Corepressor Recognition by Antagonist-bound Estrogen Receptors

DAX-1 Functions as an LXXLL-containing Corepressor for Activated Estrogen Receptors

E3 Ubiquitin Ligase RNF31 Cooperates with DAX-1 in Transcriptional Repression of Steroidogenesis

Glucocorticoid Signaling Is Perturbed by the Atypical Orphan Receptor and Corepressor SHP

A Regulatory Role for RIP140 in Nuclear Receptor Activation

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