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Molecular regulation of steroidogenesis in endocrine Leydig cells

Steroids, 2015-11, Vol.103, p.3-10

Tremblay, Jacques J.

2015

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The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer's Disease in SH-SY5Y cells

PloS one, 2020-12, Vol.15 (12), p.e0237122-e0237122

2020

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CRISPR-Cas9 Gene Therapy for Duchenne Muscular Dystrophy

Neurotherapeutics, 2022-04, Vol.19 (3), p.931-941

2022

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Small-molecule inhibitors of proteasome increase CjCas9 protein stability

PloS one, 2023-01, Vol.18 (1), p.e0280353-e0280353

2023

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Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy

Pharmaceutics, 2022-10, Vol.14 (10), p.2129

2022

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Current Clinical Applications of In Vivo Gene Therapy with AAVs

Molecular therapy, 2021-02, Vol.29 (2), p.464-488

2021

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Differential Response of Transcription Factors to Activated Kinases in Steroidogenic and Non-Steroidogenic Cells

International journal of molecular sciences, 2022-11, Vol.23 (21), p.13153

2022

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A promising mouse model for Friedreich Ataxia progressing like human patients

Behavioural brain research, 2023-01, Vol.436, p.114107-114107, Article 114107

2023

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Three Decades of Clinical Gene Therapy: From Experimental Technologies to Viable Treatments

Molecular therapy, 2021-02, Vol.29 (2), p.411-412

2021

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Removal of the GAA repeat in the heart of a Friedreich’s ataxia mouse model using CjCas9

Gene therapy, 2023-08, Vol.30 (7-8), p.612-619

2023

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Prime Editing Permits the Introduction of Specific Mutations in the Gene Responsible for Duchenne Muscular Dystrophy

International journal of molecular sciences, 2022-05, Vol.23 (11), p.6160

2022

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Human Muscle Precursor Cells Form Human-Derived Myofibers in Skeletal Muscles of Nonhuman Primates: A Potential New Preclinical Setting to Test Myogenic Cells of Human Origin for Cell Therapy of Myopathies

Journal of neuropathology and experimental neurology, 2020-12, Vol.79 (12), p.1265-1275

2020

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Human MuStem cells are competent to fuse with nonhuman primate myofibers in a clinically relevant transplantation context: A proof-of-concept study

Journal of neuropathology and experimental neurology, 2024-05, Vol.83 (8), p.684-694

2024

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Comprehensive and Quantitative Analysis of the Changes in Proteomic and Phosphoproteomic Profiles during Stimulation and Repression of Steroidogenesis in MA-10 Leydig Cells

International journal of molecular sciences, 2022-11, Vol.23 (21), p.12846

2022

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Prime Editing for Human Gene Therapy: Where Are We Now?

Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.536

2023

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A Cell-Autonomous Molecular Cascade Initiated by AMP-Activated Protein Kinase Represses Steroidogenesis

Molecular and cellular biology, 2014-12, Vol.34 (23), p.4257-4271

2014

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Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A₂-IIA

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.E3564-E3573

2015

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Gene therapy for Duchenne muscular dystrophy: an update on the latest clinical developments

Expert review of neurotherapeutics, 2023-10, Vol.23 (10), p.905-920

2023

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Serum extracellular vesicles for delivery of CRISPR-CAS9 ribonucleoproteins to modify the dystrophin gene

Molecular therapy, 2022-07, Vol.30 (7), p.2429-2442

2022

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A 35-bp Conserved Region Is Crucial for Insl3 Promoter Activity in Mouse MA-10 Leydig Cells

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15060

2022

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Limb-Girdle Muscular Dystrophies Classification and Therapies

Journal of clinical medicine, 2023-07, Vol.12 (14), p.4769

2023

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Cell therapy in muscular dystrophies: many promises in mice and dogs, few facts in patients

Expert opinion on biological therapy, 2015-09, Vol.15 (9), p.1307-1319

2015

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Transcription Factors in the Regulation of Leydig Cell Gene Expression and Function

Frontiers in endocrinology (Lausanne), 2022-04, Vol.13, p.881309-881309

2022

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A Short Promoter Region Containing Conserved Regulatory Motifs Is Required for Steroidogenic Acute Regulatory Protein (Star) Gene Expression in the Mouse Testis

International journal of molecular sciences, 2022-10, Vol.23 (19), p.12009

2022

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CRISPR-SCReT (CRISPR-Stop Codon Read Through) method to control Cas9 expression for gene editing

Gene therapy, 2022-04, Vol.29 (3-4), p.171-177

2022

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Molecular regulation of steroidogenesis in endocrine Leydig cells

The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer's Disease in SH-SY5Y cells

CRISPR-Cas9 Gene Therapy for Duchenne Muscular Dystrophy

Small-molecule inhibitors of proteasome increase CjCas9 protein stability

Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy

Current Clinical Applications of In Vivo Gene Therapy with AAVs

Differential Response of Transcription Factors to Activated Kinases in Steroidogenic and Non-Steroidogenic Cells

A promising mouse model for Friedreich Ataxia progressing like human patients

Three Decades of Clinical Gene Therapy: From Experimental Technologies to Viable Treatments

Removal of the GAA repeat in the heart of a Friedreich’s ataxia mouse model using CjCas9

Prime Editing Permits the Introduction of Specific Mutations in the Gene Responsible for Duchenne Muscular Dystrophy

Human Muscle Precursor Cells Form Human-Derived Myofibers in Skeletal Muscles of Nonhuman Primates: A Potential New Preclinical Setting to Test Myogenic Cells of Human Origin for Cell Therapy of Myopathies

Human MuStem cells are competent to fuse with nonhuman primate myofibers in a clinically relevant transplantation context: A proof-of-concept study

Comprehensive and Quantitative Analysis of the Changes in Proteomic and Phosphoproteomic Profiles during Stimulation and Repression of Steroidogenesis in MA-10 Leydig Cells

Prime Editing for Human Gene Therapy: Where Are We Now?

A Cell-Autonomous Molecular Cascade Initiated by AMP-Activated Protein Kinase Represses Steroidogenesis

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A₂-IIA

Gene therapy for Duchenne muscular dystrophy: an update on the latest clinical developments

Serum extracellular vesicles for delivery of CRISPR-CAS9 ribonucleoproteins to modify the dystrophin gene

A 35-bp Conserved Region Is Crucial for Insl3 Promoter Activity in Mouse MA-10 Leydig Cells

Limb-Girdle Muscular Dystrophies Classification and Therapies

Cell therapy in muscular dystrophies: many promises in mice and dogs, few facts in patients

Transcription Factors in the Regulation of Leydig Cell Gene Expression and Function

A Short Promoter Region Containing Conserved Regulatory Motifs Is Required for Steroidogenic Acute Regulatory Protein (Star) Gene Expression in the Mouse Testis

CRISPR-SCReT (CRISPR-Stop Codon Read Through) method to control Cas9 expression for gene editing

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