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Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides

The Journal of cell biology, 2016-04, Vol.213 (1), p.33-48

2016

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Control of TMEM16A by INO‐4995 and other inositolphosphates

British journal of pharmacology, 2013-01, Vol.168 (1), p.253-265

2013

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INO-4995 Therapeutic Efficacy Is Enhanced with Repeat Dosing in Cystic Fibrosis Knockout Mice and Human Epithelia

American journal of respiratory cell and molecular biology, 2010-01, Vol.42 (1), p.105-112

2010

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An inositol tetrakisphosphate-containing phospholipid in activated neutrophils

Nature (London), 1988-07, Vol.334 (6180), p.353-356

1988

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Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia

American Journal of Physiology: Cell Physiology, 2005-09, Vol.289 (3), p.C512-C520

2005

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A Tyrosine Kinase Signaling Pathway Accounts for the Majority of Phosphatidylinositol 3,4,5-Trisphosphate Formation in Chemoattractant-stimulated Human Neutrophils

The Journal of biological chemistry, 1996-10, Vol.271 (41), p.25204-25207

1996

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Antagonists of myo-inositol 3,4,5,6-tetrakisphosphate allow repeated epithelial chloride secretion

Bioorganic & medicinal chemistry, 2003-07, Vol.11 (15), p.3315-3329

2003

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D-myo-Inositol 1,4,5,6-Tetrakisphosphate Produced in Human Intestinal Epithelial Cells in Response to Salmonella Invasion Inhibits Phosphoinositide 3-Kinase Signaling Pathways

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (26), p.14456-14460

1997

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Phosphatidylinositol 3-Kinase Mediates the Inhibitory Effect of Epidermal Growth Factor on Calcium-dependent Chloride Secretion

The Journal of biological chemistry, 1996-10, Vol.271 (43), p.26588-26595

1996

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2-Deoxy Derivative Is a Partial Agonist of the Intracellular Messenger Inositol 3,4,5,6-Tetrakisphosphate in the Epithelial Cell Line T84

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3635-3644

1998

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Dynamic formation of ER–PM junctions presents a lipid phosphatase to regulate phosphoinositides

The Journal of general physiology, 2016-05, Vol.147 (5), p.1475

2016

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A membrane-permeant, bioactivatable derivative of INS(1,3,4)P3 and its effect on Cl--secretion from T84 cells

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (14), p.1857-1860

1998

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Activation of Human Neutrophil NADPH Oxidase by Phosphatidic Acid or Diacylglycerol in a Cell-free System

The Journal of biological chemistry, 1999-08, Vol.274 (32), p.22243-22250

1999

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Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

Biochemical journal, 1996-05, Vol.315 ( Pt 3) (3), p.775-779

1996

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Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase

The Journal of immunology (1950), 1995-03, Vol.154 (5), p.2413-2422

1995

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Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells

American Journal of Physiology: Cell Physiology, 1996-09, Vol.271 (3), p.C914-C922

1996

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Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid

The Journal of biological chemistry, 1999-08, Vol.274 (32), p.22243

1999

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Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?

The Journal of biological chemistry, 1990-10, Vol.265 (28), p.16725-16728

1990

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Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells

The Journal of clinical investigation, 1995-07, Vol.96 (1), p.386-393

1995

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2-Deoxy Derivative Is a Partial Agonist of the Intracellular Messenger Inositol 3,4,5,6-Tetrakisphosphate in the Epithelial Cell Line T 84

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3635-3644

1998

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A membrane-permeant, bioactivatable derivative of Ins(1,3,4)P 3 and its effect on Cl −-secretion from T 84 cells

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (14), p.1857-1860

1998

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Dual role for AlF4(-)-sensitive G proteins in the function of T84 epithelial cells: transport and barrier effects

American Journal of Physiology: Cell Physiology, 1997-03, Vol.272 (3), p.C794-C803

1997

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Activation by calcium alone of chloride secretion in T84 epithelial cells

British journal of pharmacology, 1993-06, Vol.109 (2), p.510-517

1993

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C5a reduces formyl peptide-induced actin polymerization and phosphatidylinositol(3,4,5)trisphosphate formation, but not phosphatidylinositol (4,5) bisphosphate hydrolysis and superoxide production, in human neutrophils

The Journal of immunology (1950), 1992-07, Vol.149 (2), p.609-614

1992

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Actin Polymerization, Calcium-Transients, and Phospholipid Metabolism in Human Neutrophils After Stimulation with Interleukin-8 and N-formyl Peptide

Journal of investigative dermatology, 1994-03, Vol.102 (3), p.310-314

1994

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Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides

Control of TMEM16A by INO‐4995 and other inositolphosphates

INO-4995 Therapeutic Efficacy Is Enhanced with Repeat Dosing in Cystic Fibrosis Knockout Mice and Human Epithelia

An inositol tetrakisphosphate-containing phospholipid in activated neutrophils

Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia

A Tyrosine Kinase Signaling Pathway Accounts for the Majority of Phosphatidylinositol 3,4,5-Trisphosphate Formation in Chemoattractant-stimulated Human Neutrophils

Antagonists of myo-inositol 3,4,5,6-tetrakisphosphate allow repeated epithelial chloride secretion

D-myo-Inositol 1,4,5,6-Tetrakisphosphate Produced in Human Intestinal Epithelial Cells in Response to Salmonella Invasion Inhibits Phosphoinositide 3-Kinase Signaling Pathways

Phosphatidylinositol 3-Kinase Mediates the Inhibitory Effect of Epidermal Growth Factor on Calcium-dependent Chloride Secretion

2-Deoxy Derivative Is a Partial Agonist of the Intracellular Messenger Inositol 3,4,5,6-Tetrakisphosphate in the Epithelial Cell Line T84

Dynamic formation of ER–PM junctions presents a lipid phosphatase to regulate phosphoinositides

A membrane-permeant, bioactivatable derivative of INS(1,3,4)P3 and its effect on Cl--secretion from T84 cells

Activation of Human Neutrophil NADPH Oxidase by Phosphatidic Acid or Diacylglycerol in a Cell-free System

Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase

Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells

Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid

Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?

Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells

2-Deoxy Derivative Is a Partial Agonist of the Intracellular Messenger Inositol 3,4,5,6-Tetrakisphosphate in the Epithelial Cell Line T 84

A membrane-permeant, bioactivatable derivative of Ins(1,3,4)P 3 and its effect on Cl −-secretion from T 84 cells

Dual role for AlF4(-)-sensitive G proteins in the function of T84 epithelial cells: transport and barrier effects

Activation by calcium alone of chloride secretion in T84 epithelial cells

C5a reduces formyl peptide-induced actin polymerization and phosphatidylinositol(3,4,5)trisphosphate formation, but not phosphatidylinositol (4,5) bisphosphate hydrolysis and superoxide production, in human neutrophils

Actin Polymerization, Calcium-Transients, and Phospholipid Metabolism in Human Neutrophils After Stimulation with Interleukin-8 and N-formyl Peptide

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