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Development and validation of a LC–MS/MS assay for quantification of cisplatin in rat plasma and urine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-03, Vol.1046, p.243-249

2017

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Nonlinear Mixed‐Effects Model Development and Simulation Using nlmixr and Related R Open‐Source Packages

CPT: pharmacometrics and systems pharmacology, 2019-09, Vol.8 (9), p.621-633

2019

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Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds

British journal of clinical pharmacology, 2016-01, Vol.81 (1), p.137-147

2016

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Covariate modeling in pharmacometrics: General points for consideration

CPT: pharmacometrics and systems pharmacology, 2024-05, Vol.13 (5), p.710-728

2024

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A case study of a patient‐centered reverse translational systems‐based approach to understand adverse event profiles in drug development

Clinical and translational science, 2022-04, Vol.15 (4), p.1003-1013

2022

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Application of a patient‐centered reverse translational systems‐based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors

Clinical and translational science, 2022-06, Vol.15 (6), p.1430-1438

2022

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Population Pharmacokinetics of Escalating Doses of Caspofungin in a Phase II Study of Patients with Invasive Aspergillosis

Antimicrobial Agents and Chemotherapy, 2013-04, Vol.57 (4), p.1664-1671

2013

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A Semi‐Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy

CPT: pharmacometrics and systems pharmacology, 2018-09, Vol.7 (9), p.581-592

2018

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Population Pharmacokinetics of Liposomal Amphotericin B and Caspofungin in Allogeneic Hematopoietic Stem Cell Recipients

Antimicrobial Agents and Chemotherapy, 2012-01, Vol.56 (1), p.536-543

2012

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Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr

CPT: pharmacometrics and systems pharmacology, 2019-12, Vol.8 (12), p.923-930

2019

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Semi-Mechanistic Pharmacokinetic Model to Guide the Dose Selection of Nimotuzumab in Patients with Autosomal Dominant Polycystic Kidney Disease

Pharmaceutics, 2020-11, Vol.12 (12), p.1147

2020

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An Integrated Bioinformatics and Quantitative Modeling Approach to Investigate Potential Claims of Oral Generic Drug Product Bioinequivalence: Introduction

Journal of clinical pharmacology, 2019-09, Vol.59 (9), p.1245-1248

2019

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Systems pharmacology to predict drug safety in drug development

European journal of pharmaceutical sciences, 2016-10, Vol.94, p.93-95

2016

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Physiologically Based Pharmacokinetic Modeling to Evaluate Formulation Factors Influencing Bioequivalence of Metoprolol Extended‐Release Products

Journal of clinical pharmacology, 2019-09, Vol.59 (9), p.1252-1263

2019

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Semi‐mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities

British journal of pharmacology, 2020-08, Vol.177 (15), p.3568-3590

2020

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Population Pharmacokinetics of Busulfan in Children: Increased Evidence for Body Surface Area and Allometric Body Weight Dosing of Busulfan in Children

Clinical cancer research, 2011-11, Vol.17 (21), p.6867-6877

2011

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A Comprehensive Review of Novel Drug–Disease Models in Diabetes Drug Development

Clinical pharmacokinetics, 2016-07, Vol.55 (7), p.769-788

2016

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Is Bioequivalence Established Based on the Reference‐Scaled Average Bioequivalence Approach Relevant to Chronic Administration of Phenytoin? Perspectives Based on Population Pharmacokinetic Modeling and Simulations

Journal of clinical pharmacology, 2019-08, Vol.59 (8), p.1061-1069

2019

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The American Conference on Pharmacometrics 2016 (ACoP7)

Journal of pharmacokinetics and pharmacodynamics, 2016-10, Vol.43 (Suppl 1), p.1-2

2016

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A pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans

Journal of pharmacokinetics and pharmacodynamics, 2018-12, Vol.45 (6), p.817-827

2018

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A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus

Journal of pharmacokinetics and pharmacodynamics, 2020-06, Vol.47 (3), p.255-266

2020

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Evaluating the Clinical Impact of Formulation Variability: A Metoprolol Extended‐Release Case Study

Journal of clinical pharmacology, 2019-09, Vol.59 (9), p.1266-1274

2019

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Model‐Based Approach to Predict Adherence to Protocol During Antiobesity Trials

Journal of clinical pharmacology, 2018-02, Vol.58 (2), p.240-253

2018

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Evaluation of effects of busulfan and DMA on SOS in pediatric stem cell recipients

Pediatric blood & cancer, 2014-02, Vol.61 (2), p.306-311

2014

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Population pharmacokinetics of dimethylacetamide in children during standard and once-daily IV busulfan administration

Cancer chemotherapy and pharmacology, 2013-11, Vol.72 (5), p.1149-1155

2013

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Development and validation of a LC–MS/MS assay for quantification of cisplatin in rat plasma and urine

Nonlinear Mixed‐Effects Model Development and Simulation Using nlmixr and Related R Open‐Source Packages

Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds

Covariate modeling in pharmacometrics: General points for consideration

A case study of a patient‐centered reverse translational systems‐based approach to understand adverse event profiles in drug development

Application of a patient‐centered reverse translational systems‐based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors

Population Pharmacokinetics of Escalating Doses of Caspofungin in a Phase II Study of Patients with Invasive Aspergillosis

A Semi‐Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy

Population Pharmacokinetics of Liposomal Amphotericin B and Caspofungin in Allogeneic Hematopoietic Stem Cell Recipients

Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr

Semi-Mechanistic Pharmacokinetic Model to Guide the Dose Selection of Nimotuzumab in Patients with Autosomal Dominant Polycystic Kidney Disease

An Integrated Bioinformatics and Quantitative Modeling Approach to Investigate Potential Claims of Oral Generic Drug Product Bioinequivalence: Introduction

Systems pharmacology to predict drug safety in drug development

Physiologically Based Pharmacokinetic Modeling to Evaluate Formulation Factors Influencing Bioequivalence of Metoprolol Extended‐Release Products

Semi‐mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities

Population Pharmacokinetics of Busulfan in Children: Increased Evidence for Body Surface Area and Allometric Body Weight Dosing of Busulfan in Children

A Comprehensive Review of Novel Drug–Disease Models in Diabetes Drug Development

Is Bioequivalence Established Based on the Reference‐Scaled Average Bioequivalence Approach Relevant to Chronic Administration of Phenytoin? Perspectives Based on Population Pharmacokinetic Modeling and Simulations

The American Conference on Pharmacometrics 2016 (ACoP7)

A pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans

A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus

Evaluating the Clinical Impact of Formulation Variability: A Metoprolol Extended‐Release Case Study

Model‐Based Approach to Predict Adherence to Protocol During Antiobesity Trials

Evaluation of effects of busulfan and DMA on SOS in pediatric stem cell recipients

Population pharmacokinetics of dimethylacetamide in children during standard and once-daily IV busulfan administration

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