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Development of an in vitro photosafety evaluation method utilizing intracellular ROS production in THP-1 cells

The Journal of Toxicological Sciences, 2018, Vol.43(4), pp.247-256

2018

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Enhancing between-facility reproducibility of the SH test as an in vitro skin sensitization test by the improved test method

The Journal of Toxicological Sciences, 2021, Vol.46(5), pp.235-248

2021

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Development of a modified 3T3 Neutral Red Uptake Phototoxicity Test protocol for evaluation of poorly water-soluble substances

The Journal of Toxicological Sciences, 2017/10/01, Vol.42(5), pp.569-577

2017

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Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization

Journal of applied toxicology, 2015-11, Vol.35 (11), p.1333-1347

2015

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Comparative assessment of 24-hr primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan)

The Journal of Toxicological Sciences, 2018, Vol.43(12), pp.751-768

2018

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Second-phase validation study of short time exposure test for assessment of eye irritation potency of chemicals

Toxicology in vitro, 2013-09, Vol.27 (6), p.1855-1869

2013

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Culture insert device with perfusable microchannels enhances in vitro skin model development and barrier function assessment

Biofabrication, 2024-07, Vol.16 (3)

2024

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S3-1. Next generation risk assessment of cosmetics using NAMs at The Japan Cosmetic Industry Association NGRA WG

Alternatives to Animal Testing and Experimentation, 2023-12, Vol.28 (suppl), p.91-91

Akemi Toyoda

2023

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Upregulation of CD86 and IL-12 by rhododendrol in THP-1 cells cocultured with melanocytes through ROS and ATP

Journal of dermatological science, 2022-12, Vol.108 (3), p.167-177

2022

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Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals

Journal of applied toxicology, 2015-11, Vol.35 (11), p.1318-1332

2015

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Culture insert device with perfusable microchannels enhancesin vitroskin model development and barrier function assessment

Biofabrication, 2024-04, Vol.16 (3)

2024

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Improved performance of the SH test as an in vitro skin sensitization test with a new predictive model and decision tree

Journal of applied toxicology, 2022-06, Vol.42 (6), p.1029-1043

2022

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Current Issues in Photosafety Evaluation

YAKUGAKU ZASSHI, 2021/01/01, Vol.141(1), pp.111-124

2021

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Current Issues in Photosafety Evaluation

Yakugaku zasshi, 2021-01, Vol.141 (1), p.111-124

2021

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S6-3. Issues and Future Prospects in Safety Evaluation of Cosmetic Development Utilizing Alternative Animal Experiment Method

Alternatives to Animal Testing and Experimentation, 2018-12, Vol.23 (suppl), p.102-102

Akemi Toyoda

2018

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光安全性評価の現状と課題

YAKUGAKU ZASSHI, 2021/01/01, Vol.141(1), pp.111-124

2021

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P-11. Development of tyrosinase-dependent protein binding assay with combination of ADRA method and in vitro tyrosinase metabolism assay

Alternatives to Animal Testing and Experimentation, 2021-12, Vol.26 (suppl), p.115-115

2021

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P-24 Effect of reactive oxygen species quenchers on in vitro photoallergenicity evaluation

Alternatives to Animal Testing and Experimentation, 2015-12, Vol.20 (suppl), p.143-143

2015

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P-15 Study of intracellular ROS production with photoreactivity

Alternatives to Animal Testing and Experimentation, 2016-12, Vol.21 (suppl), p.127-127

2016

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P-23 The feasibility of technology transfer of in vitro sensitization test, SH test (Part 2)

Alternatives to Animal Testing and Experimentation, 2016-12, Vol.21 (suppl), p.131-131

2016

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P-21 Evaluation of skin sensitizer potency prediction model combining multiple in vitro tests

Alternatives to Animal Testing and Experimentation, 2016-12, Vol.21 (suppl), p.130-130

2016

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P-70 The feasibility of technology transfer of in vitro sensitization test, SH test (Part 3)

Alternatives to Animal Testing and Experimentation, 2017-12, Vol.22 (suppl), p.90-90

2017

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S1-3 The point of the guidance for three kinds of Local Lymph Node Assays

Alternatives to Animal Testing and Experimentation, 2014-12, Vol.19 (suppl), p.110-110

2014

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P-13 Modeification of the 3T3 NRU photo-toxicity test conditions for the evaluation of poorly water-soluble substances (part 2)

Alternatives to Animal Testing and Experimentation, 2014-12, Vol.19 (suppl), p.171-171

2014

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P-7 Working Group's Report - Alternative Primary Irritation Test

Alternatives to Animal Testing and Experimentation, 2015-12, Vol.20 (suppl), p.134-134

2015

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Development of an in vitro photosafety evaluation method utilizing intracellular ROS production in THP-1 cells

Enhancing between-facility reproducibility of the SH test as an in vitro skin sensitization test by the improved test method

Development of a modified 3T3 Neutral Red Uptake Phototoxicity Test protocol for evaluation of poorly water-soluble substances

Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization

Comparative assessment of 24-hr primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan)

Second-phase validation study of short time exposure test for assessment of eye irritation potency of chemicals

Culture insert device with perfusable microchannels enhances in vitro skin model development and barrier function assessment

S3-1. Next generation risk assessment of cosmetics using NAMs at The Japan Cosmetic Industry Association NGRA WG

Upregulation of CD86 and IL-12 by rhododendrol in THP-1 cells cocultured with melanocytes through ROS and ATP

Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals

Culture insert device with perfusable microchannels enhancesin vitroskin model development and barrier function assessment

Improved performance of the SH test as an in vitro skin sensitization test with a new predictive model and decision tree

Current Issues in Photosafety Evaluation

Current Issues in Photosafety Evaluation

S6-3. Issues and Future Prospects in Safety Evaluation of Cosmetic Development Utilizing Alternative Animal Experiment Method

光安全性評価の現状と課題

P-11. Development of tyrosinase-dependent protein binding assay with combination of ADRA method and in vitro tyrosinase metabolism assay

P-24 Effect of reactive oxygen species quenchers on in vitro photoallergenicity evaluation

P-15 Study of intracellular ROS production with photoreactivity

P-23 The feasibility of technology transfer of in vitro sensitization test, SH test (Part 2)

P-21 Evaluation of skin sensitizer potency prediction model combining multiple in vitro tests

P-70 The feasibility of technology transfer of in vitro sensitization test, SH test (Part 3)

S1-3 The point of the guidance for three kinds of Local Lymph Node Assays

P-13 Modeification of the 3T3 NRU photo-toxicity test conditions for the evaluation of poorly water-soluble substances (part 2)

P-7 Working Group's Report - Alternative Primary Irritation Test

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