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Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

Biochemical journal, 2012-04, Vol.443 (1), p.111-123

2012

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Glucose as a regulator of eukaryotic gene transcription

Trends in endocrinology and metabolism, 2005-12, Vol.16 (10), p.489-494

Towle, Howard C.

2005

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Glucose Activates ChREBP by Increasing Its Rate of Nuclear Entry and Relieving Repression of Its Transcriptional Activity

The Journal of biological chemistry, 2008-08, Vol.283 (35), p.24029-24038

2008

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ChREBP•Mlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver

The Journal of biological chemistry, 2006-09, Vol.281 (39), p.28721-28730

2006

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Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.15662-15669

2004

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Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α

Cell cycle (Georgetown, Tex.), 2012-07, Vol.11 (14), p.2681-2690

2012

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Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis

Diabetes (New York, N.Y.), 2011-12, Vol.60 (12), p.3110-3120

2011

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The Role of SREBP-1c in Nutritional Regulation of Lipogenic Enzyme Gene Expression

The Journal of biological chemistry, 2002-07, Vol.277 (30), p.27029-27035

2002

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Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism

Biochemical and biophysical research communications, 2006-02, Vol.340 (2), p.449-456

2006

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Regulator of G Protein Signaling (RGS16) Inhibits Hepatic Fatty Acid Oxidation in a Carbohydrate Response Element-binding Protein (ChREBP)-dependent Manner

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.15116-15125

2011

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Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter

Molecular and Cellular Biology, 2013-02, Vol.33 (4), p.725-738

2013

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Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.12019-12027

2005

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Activation and repression of glucose-stimulated ChREBP requires the concerted action of multiple domains within the MondoA conserved region

American journal of physiology: endocrinology and metabolism, 2010-10, Vol.299 (4), p.E665-E674

2010

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Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP

Biochemical journal, 2008-04, Vol.411 (2), p.261-270

2008

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The Metabolic Sensor GCN2 Branches out

Cell metabolism, 2007-02, Vol.5 (2), p.85-87

Towle, Howard C.

2007

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Overlapping Roles of the Glucose-Responsive Genes, S14 and S14R, in Hepatic Lipogenesis

Endocrinology (Philadelphia), 2010-05, Vol.151 (5), p.2071-2077

2010

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Regulation of the expression of lipogenic enzyme genes by carbohydrate

Annual review of nutrition, 1997-01, Vol.17 (1), p.405-433

1997

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A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription

Nucleic acids research, 2007-01, Vol.35 (1), p.35-44

2007

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PGC-1 β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

Molecular metabolism (Germany), 2013-08, Vol.2 (3), p.194-204

2013

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Glucose and cAMP: Adversaries in the Regulation of Hepatic Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.13476-13478

Towle, Howard C.

2001

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Hepatic Expression of the SPOT 14 (S14) Paralog S14-Related (Mid1 Interacting Protein) Is Regulated by Dietary Carbohydrate

Endocrinology (Philadelphia), 2008-10, Vol.149 (10), p.5155-5161

2008

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A Potential Role for Fructose-2,6-Bisphosphate in the Stimulation of Hepatic Glucokinase Gene Expression

Endocrinology (Philadelphia), 2004-02, Vol.145 (2), p.650-658

2004

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Glucose and Insulin Function through Two Distinct Transcription Factors to Stimulate Expression of Lipogenic Enzyme Genes in Liver

The Journal of biological chemistry, 2001-03, Vol.276 (12), p.9437-9445

2001

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Different Sterol Regulatory Element-binding Protein-1 Isoforms Utilize Distinct Co-regulatory Factors to Activate the Promoter for Fatty Acid Synthase

The Journal of biological chemistry, 2000-02, Vol.275 (7), p.4726-4733

2000

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Involvement of a Unique Carbohydrate-responsive Factor in the Glucose Regulation of Rat Liver Fatty-acid Synthase Gene Transcription

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21969-21975

2001

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Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

Glucose as a regulator of eukaryotic gene transcription

Glucose Activates ChREBP by Increasing Its Rate of Nuclear Entry and Relieving Repression of Its Transcriptional Activity

ChREBP•Mlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver

Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes

Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α

Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis

The Role of SREBP-1c in Nutritional Regulation of Lipogenic Enzyme Gene Expression

Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism

Regulator of G Protein Signaling (RGS16) Inhibits Hepatic Fatty Acid Oxidation in a Carbohydrate Response Element-binding Protein (ChREBP)-dependent Manner

Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter

Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes

Activation and repression of glucose-stimulated ChREBP requires the concerted action of multiple domains within the MondoA conserved region

Identification and function of phosphorylation in the glucose-regulated transcription factor ChREBP

The Metabolic Sensor GCN2 Branches out

Overlapping Roles of the Glucose-Responsive Genes, S14 and S14R, in Hepatic Lipogenesis

Regulation of the expression of lipogenic enzyme genes by carbohydrate

A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription

PGC-1 β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

Glucose and cAMP: Adversaries in the Regulation of Hepatic Gene Expression

Hepatic Expression of the SPOT 14 (S14) Paralog S14-Related (Mid1 Interacting Protein) Is Regulated by Dietary Carbohydrate

A Potential Role for Fructose-2,6-Bisphosphate in the Stimulation of Hepatic Glucokinase Gene Expression

Glucose and Insulin Function through Two Distinct Transcription Factors to Stimulate Expression of Lipogenic Enzyme Genes in Liver

Different Sterol Regulatory Element-binding Protein-1 Isoforms Utilize Distinct Co-regulatory Factors to Activate the Promoter for Fatty Acid Synthase

Involvement of a Unique Carbohydrate-responsive Factor in the Glucose Regulation of Rat Liver Fatty-acid Synthase Gene Transcription

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