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Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL–positive acute lymphoblastic leukemia

Blood, 2004-12, Vol.104 (12), p.3507-3512

2004

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Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

Leukemia, 1998-09, Vol.12 (9), p.1333-1337

1998

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Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells

Blood, 2000-12, Vol.96 (12), p.3847-3856

2000

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Lyn is an important component of the signal transduction pathway specific to FLT3 ITD and can be a therapeutic target in the treatment of AML with FLT3 ITD

Leukemia, 2007-03, Vol.21 (3), p.403-410

2007

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Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia : a new approach to anti-leukemia therapy

Leukemia, 1999-09, Vol.13 (9), p.1316-1324

1999

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Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12)

Blood, 2001-02, Vol.97 (4), p.1050-1055

2001

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Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

Leukemia, 1997-04, Vol.11 (4), p.479-484

1997

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Potentiation of GATA-2 Activity through Interactions with the Promyelocytic Leukemia Protein (PML) and the t(15;17)-Generated PML-Retinoic Acid Receptor α Oncoprotein

Molecular and Cellular Biology, 2000-09, Vol.20 (17), p.6276-6286

2000

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TEL-Syk fusion constitutively activates P13-K/Akt, MAPK and JAK2-independent STAT5 signal pathways

Leukemia, 2004, Vol.18 (3), p.548-555

2004

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Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (20), p.10838-10843

1996

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In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

Leukemia, 2000-03, Vol.14 (3), p.374-378

2000

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Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

Oncogene, 2000-02, Vol.19 (5), p.624-631

2000

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Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation

Leukemia, 1999-04, Vol.13 (4), p.585-589

1999

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Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation

Oncogene, 2003-12, Vol.22 (57), p.9176-9184

2003

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Functional regulation of GATA-2 by acetylation

Journal of leukocyte biology, 2004-03, Vol.75 (3), p.529-540

Hayakawa, F.

2004

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Histone deacetylase 3 associates with and represses the transcription factor GATA-2

Blood, 2001-10, Vol.98 (7), p.2116-2123

2001

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Life‐threatening human parvovirus B19 infection transmitted by intravenous immune globulin

British journal of haematology, 2002-09, Vol.118 (4), p.1187-1189

2002

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c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300

Oncogene, 2000-01, Vol.19 (3), p.444-451

2000

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In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice

Cancer science, 2001-05, Vol.92 (5), p.529-536

2001

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TEL-Syk fusion constitutively activates PI3-K Akt, MAPK and JAK2-independent STAT5 signal pathways

Leukemia, 2004-03, Vol.18 (3), p.548-555

2004

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Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype

Leukemia, 2003-12, Vol.17 (12), p.2492-2499

2003

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Constitutive activation of MAP kinase pathway and STAT pathway in AML

Rinshō ketsueki, 1998-02, Vol.39 (2), p.86

1998

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Apoptotic Cytotoxic Effects of a Histone Deacetylase Inhibitor, FK228, on Malignant Lymphoid Cells

Cancer science, 2000-11, Vol.91 (11), p.1154-1160

2000

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Histone Acetylation Induced by Granulocyte Colony-Stimulating Factor in a MAP Kinase-Dependent Manner

Biochemical and biophysical research communications, 2001-05, Vol.283 (3), p.655-660

2001

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Overexpression of Cyclin E in Acute Myelogenous Leukemia

Blood, 1997-11, Vol.90 (9), p.3707-3713

1997

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Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL–positive acute lymphoblastic leukemia

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells

Lyn is an important component of the signal transduction pathway specific to FLT3 ITD and can be a therapeutic target in the treatment of AML with FLT3 ITD

Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia : a new approach to anti-leukemia therapy

Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12)

Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

Potentiation of GATA-2 Activity through Interactions with the Promyelocytic Leukemia Protein (PML) and the t(15;17)-Generated PML-Retinoic Acid Receptor α Oncoprotein

TEL-Syk fusion constitutively activates P13-K/Akt, MAPK and JAK2-independent STAT5 signal pathways

Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation

Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation

Functional regulation of GATA-2 by acetylation

Histone deacetylase 3 associates with and represses the transcription factor GATA-2

Life‐threatening human parvovirus B19 infection transmitted by intravenous immune globulin

c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300

In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice

TEL-Syk fusion constitutively activates PI3-K Akt, MAPK and JAK2-independent STAT5 signal pathways

Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype

Constitutive activation of MAP kinase pathway and STAT pathway in AML

Apoptotic Cytotoxic Effects of a Histone Deacetylase Inhibitor, FK228, on Malignant Lymphoid Cells

Histone Acetylation Induced by Granulocyte Colony-Stimulating Factor in a MAP Kinase-Dependent Manner

Overexpression of Cyclin E in Acute Myelogenous Leukemia

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