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An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways

Redox biology, 2015-08, Vol.5, p.43-65

2015

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Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance

Frontiers in microbiology, 2018-07, Vol.9, p.1699-1699

2018

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Simultaneous determination of LY3214996, abemaciclib, and M2 and M20 metabolites in human plasma, cerebrospinal fluid, and brain tumor by LC-MS/MS

Journal of pharmaceutical analysis, 2022-08, Vol.12 (4), p.601-609

2022

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Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II) N-Alkylpyridylporphyrins

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36579-36588

2013

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Antibacterial Activity of Synthetic Cationic Iron Porphyrins

Antioxidants, 2020-10, Vol.9 (10), p.972

2020

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Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes

Redox report : communications in free radical research, 2021-01, Vol.26 (1), p.85-93

2021

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Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

Free radical biology & medicine, 2011-09, Vol.51 (5), p.1035-1053

2011

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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics

Free radical biology & medicine, 2015-09, Vol.86, p.308-321

2015

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Post-illumination cellular effects of photodynamic treatment

PloS one, 2017-12, Vol.12 (12), p.e0188535

2017

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Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model

International journal of radiation oncology, biology, physics, 2015-11, Vol.93 (4), p.892-900

2015

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Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

Redox biology, 2018-06, Vol.16, p.344-351

2018

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Targeting mitochondria by Zn(II)N-alkylpyridylporphyrins: the impact of compound sub-mitochondrial partition on cell respiration and overall photodynamic efficacy

PloS one, 2014-09, Vol.9 (9), p.e108238

2014

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BIOM-25. DETERMINATION OF LEVELS OF SMALL MOLECULAR WEIGHT THIOLS AND DISULFIDES IN MOUSE AND HUMAN NORMAL BRAIN AND GLIOBLASTOMA TISSUE

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Suppl 7), p.vii9-vii9

2022

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CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5

Redox biology, 2017-08, Vol.12, p.864-871

2017

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Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-Based Redox Modulators

Medical principles and practice, 2013-01, Vol.22 (2), p.103-130

2013

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Novel amphiphilic cationic porphyrin and its Ag(II) complex as potential anticancer agents

Journal of inorganic biochemistry, 2014-11, Vol.140, p.94-103

2014

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Quisinostat is a brain-penetrant radiosensitizer in glioblastoma

JCI insight, 2023-11, Vol.8 (22)

2023

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Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

Journal of the American Heart Association, 2018-10, Vol.7 (20)

2018

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Folic Acid Improves Parkin-Null Drosophila Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium

Antioxidants, 2022-10, Vol.11 (10), p.2068

2022

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Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins

Dalton transactions : an international journal of inorganic chemistry, 2011-04, Vol.40 (16), p.4111-4121

2011

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Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation

Antioxidants, 2018-03, Vol.7 (3), p.40

2018

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Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP5

Redox biology, 2014-01, Vol.2 (C), p.400-410

2014

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Superoxide dismutase mimic, MnTE-2-PyP5+ ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum

Redox biology, 2013-01, Vol.1 (1), p.599-607

2013

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Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications

Redox biology, 2013-01, Vol.1 (1), p.457-466

2013

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A validated LC-MS/MS method for determination of neuro-pharmacokinetic behavior of niraparib in brain tumor patients

Journal of pharmaceutical and biomedical analysis, 2024-08, Vol.245, p.116150-116150, Article 116150

2024

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An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways

Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance

Simultaneous determination of LY3214996, abemaciclib, and M2 and M20 metabolites in human plasma, cerebrospinal fluid, and brain tumor by LC-MS/MS

Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II) N-Alkylpyridylporphyrins

Antibacterial Activity of Synthetic Cationic Iron Porphyrins

Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics

Post-illumination cellular effects of photodynamic treatment

Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model

Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning

Targeting mitochondria by Zn(II)N-alkylpyridylporphyrins: the impact of compound sub-mitochondrial partition on cell respiration and overall photodynamic efficacy

BIOM-25. DETERMINATION OF LEVELS OF SMALL MOLECULAR WEIGHT THIOLS AND DISULFIDES IN MOUSE AND HUMAN NORMAL BRAIN AND GLIOBLASTOMA TISSUE

CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5

Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-Based Redox Modulators

Novel amphiphilic cationic porphyrin and its Ag(II) complex as potential anticancer agents

Quisinostat is a brain-penetrant radiosensitizer in glioblastoma

Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

Folic Acid Improves Parkin-Null Drosophila Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium

Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins

Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation

Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP5

Superoxide dismutase mimic, MnTE-2-PyP5+ ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum

Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications

A validated LC-MS/MS method for determination of neuro-pharmacokinetic behavior of niraparib in brain tumor patients

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