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Targeting RNA structures by antisense oligonucleotides

Biochimie, 1996, Vol.78 (7), p.663-673

1996

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LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1

Nucleic acids research, 2004, Vol.32 (10), p.3101-3107

2004

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In vitro selection identifies key determinants for loop–loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1

RNA (Cambridge), 1999-12, Vol.5 (12), p.1605-1614, Article S1355838299991318

1999

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Use of Dynamic Combinatorial Chemistry for the Identification of Covalently Appended Residues that Stabilize Oligonucleotide Complexes

Angewandte Chemie (International ed.), 2004-06, Vol.43 (24), p.3144-3147

2004

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Selective inhibitory DNA aptamers of the human RNase H1

Nucleic acids research, 2003-10, Vol.31 (19), p.5776-5788

2003

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DNA Aptamers Selected against the HIV-1 RNase H Display in Vitro Antiviral Activity

Biochemistry (Easton), 2001-08, Vol.40 (34), p.10087-10094

2001

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Bimodal Loop−Loop Interactions Increase the Affinity of RNA Aptamers for HIV-1 RNA Structures

Biochemistry (Easton), 2006-02, Vol.45 (5), p.1518-1524

2006

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Is a Closing “GA Pair” a Rule for Stable Loop-Loop RNA Complexes?

The Journal of biological chemistry, 2000-07, Vol.275 (28), p.21287-21294

2000

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Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation

Nucleic acids research, 2003-01, Vol.31 (2), p.734-742

2003

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DNA aptamers selected against the HIV-1 trans-activation-responsive RNA element form RNA-DNA kissing complexes

The Journal of biological chemistry, 1999-04, Vol.274 (18), p.12730-12737

1999

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Apical Loop−Internal Loop Interactions: A New RNA−RNA Recognition Motif Identified through in Vitro Selection against RNA Hairpins of the Hepatitis C Virus mRNA

Biochemistry (Easton), 2002-05, Vol.41 (18), p.5883-5893

2002

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2‘-O-Methyl-RNA Hairpins Generate Loop−Loop Complexes and Selectively Inhibit HIV-1 Tat-Mediated Transcription

Biochemistry (Easton), 2002-10, Vol.41 (40), p.12186-12192

2002

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Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR-TAR and TAR-aptamer

Nucleic acids research, 2003-07, Vol.31 (14), p.4275-4284

2003

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Hexitol Nucleic Acid-Containing Aptamers Are Efficient Ligands of HIV-1 TAR RNA

Biochemistry (Easton), 2005-03, Vol.44 (8), p.2926-2933

2005

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New candidates for true antisense

Nature biotechnology, 2001-01, Vol.19 (1), p.17-18

Toulme, Jean-Jacques

2001

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Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (15), p.9709-9714

2002

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Regulating eukaryotic gene expression with aptamers

FEBS Letters, 2004-06, Vol.567 (1), p.55-62

2004

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Benzoquinazoline Derivatives as Substitutes for Thymine in Nucleic Acid Complexes. Use of Fluorescence Emission of Benzo[g]quinazoline-2,4-(1H,3H)-dione in Probing Duplex and Triplex Formation

Biochemistry (Easton), 1998-09, Vol.37 (39), p.13765-13775

1998

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Facets of the RNA world

Biochimie, 2005-09, Vol.87 (9), p.791-791

Toulmé, J.J.

2005

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4-amino-1H-benzo[g]quinazoline-2-one: a fluorescent analog of cytosine to probe protonation sites in triplex forming oligonucleotides

Nucleic acids research, 2000-08, Vol.28 (15), p.2977

2000

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Modulating viral gene expression by aptamers to RNA structures

Biology of the Cell, 2003-05, Vol.95 (3), p.229-238

2003

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NMR characterization of a kissing complex formed between the TAR RNA element of HIV-1 and a DNA aptamer

Nucleic acids research, 2000-09, Vol.28 (17), p.3386-3391

2000

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Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription

Nucleic acids research, 1998-12, Vol.26 (23), p.5492-5500

1998

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Comparative Analysis of Translation Efficiencies of Hepatitis C Virus 5′ Untranslated Regions among Intraindividual Quasispecies Present in Chronic Infection: Opposite Behaviors Depending on Cell Type

Journal of Virology, 2000-11, Vol.74 (22), p.10827-10833

2000

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Mapping of a Minimal AU-rich Sequence Required for Lipopolysaccharide-induced Binding of a 55-kDa Protein on Tumor Necrosis Factor-α mRNA

The Journal of biological chemistry, 1998-05, Vol.273 (22), p.13781-13786

1998

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Targeting RNA structures by antisense oligonucleotides

LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1

In vitro selection identifies key determinants for loop–loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1

Use of Dynamic Combinatorial Chemistry for the Identification of Covalently Appended Residues that Stabilize Oligonucleotide Complexes

Selective inhibitory DNA aptamers of the human RNase H1

DNA Aptamers Selected against the HIV-1 RNase H Display in Vitro Antiviral Activity

Bimodal Loop−Loop Interactions Increase the Affinity of RNA Aptamers for HIV-1 RNA Structures

Is a Closing “GA Pair” a Rule for Stable Loop-Loop RNA Complexes?

Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation

DNA aptamers selected against the HIV-1 trans-activation-responsive RNA element form RNA-DNA kissing complexes

Apical Loop−Internal Loop Interactions: A New RNA−RNA Recognition Motif Identified through in Vitro Selection against RNA Hairpins of the Hepatitis C Virus mRNA

2‘-O-Methyl-RNA Hairpins Generate Loop−Loop Complexes and Selectively Inhibit HIV-1 Tat-Mediated Transcription

Molecular dynamics reveals the stabilizing role of loop closing residues in kissing interactions: comparison between TAR-TAR and TAR-aptamer

Hexitol Nucleic Acid-Containing Aptamers Are Efficient Ligands of HIV-1 TAR RNA

New candidates for true antisense

Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription

Regulating eukaryotic gene expression with aptamers

Benzoquinazoline Derivatives as Substitutes for Thymine in Nucleic Acid Complexes. Use of Fluorescence Emission of Benzo[g]quinazoline-2,4-(1H,3H)-dione in Probing Duplex and Triplex Formation

Facets of the RNA world

4-amino-1H-benzo[g]quinazoline-2-one: a fluorescent analog of cytosine to probe protonation sites in triplex forming oligonucleotides

Modulating viral gene expression by aptamers to RNA structures

NMR characterization of a kissing complex formed between the TAR RNA element of HIV-1 and a DNA aptamer

Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription

Comparative Analysis of Translation Efficiencies of Hepatitis C Virus 5′ Untranslated Regions among Intraindividual Quasispecies Present in Chronic Infection: Opposite Behaviors Depending on Cell Type

Mapping of a Minimal AU-rich Sequence Required for Lipopolysaccharide-induced Binding of a 55-kDa Protein on Tumor Necrosis Factor-α mRNA

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