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Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Nature communications, 2023-07, Vol.14 (1), p.3980-3980, Article 3980

2023

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Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development

Viruses, 2024-05, Vol.16 (5), p.803

2024

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Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development

Viruses, 2021-05, Vol.13 (6), p.1027

2021

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Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

Journal of functional biomaterials, 2022-12, Vol.14 (1), p.16

2022

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Hsp70 Is a Novel Posttranscriptional Regulator of Gene Expression That Binds and Stabilizes Selected mRNAs Containing AU-Rich Elements

Molecular and Cellular Biology, 2013-01, Vol.33 (1), p.71-84

2013

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Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA

Journal of molecular biology, 2012-07, Vol.420 (3), p.164-175

2012

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Alternatively Expressed Domains of AU-rich Element RNA-binding Protein 1 (AUF1) Regulate RNA-binding Affinity, RNA-induced Protein Oligomerization, and the Local Conformation of Bound RNA Ligands

The Journal of biological chemistry, 2010-12, Vol.285 (50), p.39127-39139

2010

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A Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex Interactions

Journal of molecular biology, 2010-10, Vol.403 (3), p.351-370

2010

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Characterization of the Essential Activities of Saccharomyces cerevisiae Mtr4p, a 3′→5′ Helicase Partner of the Nuclear Exosome

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.4930-4942

2008

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Specific Protein Domains Mediate Cooperative Assembly of HuR Oligomers on AU-rich mRNA-destabilizing Sequences

The Journal of biological chemistry, 2007-07, Vol.282 (29), p.20948-20959

2007

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The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7

Molecular cell, 2003-11, Vol.12 (5), p.1113-1123

2003

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Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions

DNA repair, 2013-12, Vol.12 (12), p.1043-1052

2013

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Engineering subtilisin proteases that specifically degrade active RAS

Communications biology, 2021-03, Vol.4 (1), p.299-299, Article 299

2021

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Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies

Biotechnology advances, 2023-10, Vol.67, p.108206-108206, Article 108206

2023

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Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

Journal of molecular biology, 2008-09, Vol.382 (1), p.56-73

2008

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Prospects for developing an Hepatitis C virus E1E2-based nanoparticle vaccine

Reviews in medical virology, 2023-09, Vol.33 (5), p.e2474

2023

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Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2

Pharmaceuticals (Basel, Switzerland), 2016-01, Vol.9 (1), p.4

2016

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Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein

New biotechnology, 2024-05, Vol.80, p.27-36

2024

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Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization

Journal of virology, 2020-10, Vol.94 (22)

2020

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Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.e2112008119-e2112008119

2022

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Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor

Acta crystallographica. Section D, Biological crystallography., 2013-12, Vol.69 (12), p.2555-2562

2013

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Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (3)

2021

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A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization

The international journal of biochemistry & cell biology, 2013-04, Vol.45 (4), p.773-782

2013

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Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein

European journal of medicinal chemistry, 2016-05, Vol.113, p.273-292

2016

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Metal-Assisted and Microwave-Accelerated Evaporative Crystallization: Proof-of-Principle Application to Proteins

Crystal growth & design, 2015-07, Vol.15 (7), p.3212-3219

2015

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Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development

Structural and Biophysical Characterization of the HCV E1E2 Heterodimer for Vaccine Development

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

Hsp70 Is a Novel Posttranscriptional Regulator of Gene Expression That Binds and Stabilizes Selected mRNAs Containing AU-Rich Elements

Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA

Alternatively Expressed Domains of AU-rich Element RNA-binding Protein 1 (AUF1) Regulate RNA-binding Affinity, RNA-induced Protein Oligomerization, and the Local Conformation of Bound RNA Ligands

A Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex Interactions

Characterization of the Essential Activities of Saccharomyces cerevisiae Mtr4p, a 3′→5′ Helicase Partner of the Nuclear Exosome

Specific Protein Domains Mediate Cooperative Assembly of HuR Oligomers on AU-rich mRNA-destabilizing Sequences

The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7

Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions

Engineering subtilisin proteases that specifically degrade active RAS

Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies

Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

Prospects for developing an Hepatitis C virus E1E2-based nanoparticle vaccine

Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2

Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein

Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor

Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer

A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization

Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein

Metal-Assisted and Microwave-Accelerated Evaporative Crystallization: Proof-of-Principle Application to Proteins

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