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2. Pathological and Therapeutic Perspective in Japanese Type 2 Diabetes

Nihon Naika Gakkai Zasshi, 2022/03/10, Vol.111(3), pp.560-565

Takamura, Toshinari

2022

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Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits

Biological and Pharmaceutical Bulletin, 2018/05/01, Vol.41(5), pp.828-832

2018

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Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

Nature communications, 2017-11, Vol.8 (1), p.1658-17, Article 1658

2017

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CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

Diabetes (New York, N.Y.), 2012-07, Vol.61 (7), p.1680-1690

2012

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Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

The Journal of biological chemistry, 2009-05, Vol.284 (22), p.14809-14818

2009

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Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease

Medicine (Baltimore), 2021-08, Vol.100 (31), p.e26835-e26835

2021

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The clinical course and potential underlying mechanisms of everolimus-induced hyperglycemia

Endocrine Journal, 2019, Vol.66(7), pp.615-620

2019

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Somatostatin Receptor-negative and Fluorodeoxyglucose-positron Emission Tomography-positive Lung Neuroendocrine Tumor G1 Exhibiting Cyclic Cushing's Syndrome

Internal Medicine, 2022, pp.9238-21

2022

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Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up

Scientific reports, 2021-08, Vol.11 (1), p.16564-16564, Article 16564

2021

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Severity Indices for Obstructive Sleep Apnea Syndrome Reflecting Glycemic Control or Insulin Resistance

Internal Medicine, 2019/11/15, Vol.58(22), pp.3227-3234

2019

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Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients

Journal of gastroenterology, 2019-01, Vol.54 (1), p.64-77

2019

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Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver

Endocrine Journal, 2012, Vol.59(9), pp.745-763

2012

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Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese

PloS one, 2012-06, Vol.7 (6), p.e38322-e38322

2012

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Forkhead box protein O1 (FoxO1) knockdown accelerates the eicosapentaenoic acid (EPA)-mediated Selenop downregulation independently of sterol regulatory element-binding protein-1c (SREBP-1c) in H4IIEC3 hepatocytes

Endocrine Journal, 2022, Vol.69(8), pp.907-918

2022

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Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes

PloS one, 2011-11, Vol.6 (11), p.e27401

2011

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Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

Metabolism, clinical and experimental, 2008-08, Vol.57 (8), p.1071-1077

2008

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Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans

Biological and Pharmaceutical Bulletin, 2019/03/01, Vol.42(3), pp.373-378

2019

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A mosaic mutation of phosphate-regulating gene with homologies to endopeptidases on the X chromosome (PHEX) in X-linked hypophosphatemic rickets with mild bone phenotypes

Endocrine Journal, 2021, Vol.68(9), pp.1135-1141

2021

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Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet

Hepatology (Baltimore, Md.), 2007-11, Vol.46 (5), p.1392-1403

2007

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Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes

The Journal of pharmacology and experimental therapeutics, 2023-04, Vol.385 (1), p.5

2023

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Distinct effects of carbohydrate ingestion timing on glucose fluctuation and energy metabolism in patients with type 2 diabetes: a randomized controlled study

Endocrine Journal, 2021, Vol.68(10), pp.1225-1236

2021

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Consuming Carbohydrates after Meat or Vegetables Lowers Postprandial Excursions of Glucose and Insulin in Nondiabetic Subjects

Journal of Nutritional Science and Vitaminology, 2018/10/31, Vol.64(5), pp.316-320

2018

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Selenoprotein P deficiency protects against immobilization-induced muscle atrophy by suppressing atrophy-related E3 ubiquitin ligases

American journal of physiology: endocrinology and metabolism, 2023-06, Vol.324 (6), p.E542-E552

2023

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2. Pathological and Therapeutic Perspective in Japanese Type 2 Diabetes

Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits

Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models

CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease

The clinical course and potential underlying mechanisms of everolimus-induced hyperglycemia

Somatostatin Receptor-negative and Fluorodeoxyglucose-positron Emission Tomography-positive Lung Neuroendocrine Tumor G1 Exhibiting Cyclic Cushing's Syndrome

Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up

Severity Indices for Obstructive Sleep Apnea Syndrome Reflecting Glycemic Control or Insulin Resistance

Hepatocellular carcinoma as a leading cause of cancer-related deaths in Japanese type 2 diabetes mellitus patients

Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver

Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese

Forkhead box protein O1 (FoxO1) knockdown accelerates the eicosapentaenoic acid (EPA)-mediated Selenop downregulation independently of sterol regulatory element-binding protein-1c (SREBP-1c) in H4IIEC3 hepatocytes

Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes

Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans

A mosaic mutation of phosphate-regulating gene with homologies to endopeptidases on the X chromosome (PHEX) in X-linked hypophosphatemic rickets with mild bone phenotypes

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet

Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes

Distinct effects of carbohydrate ingestion timing on glucose fluctuation and energy metabolism in patients with type 2 diabetes: a randomized controlled study

Consuming Carbohydrates after Meat or Vegetables Lowers Postprandial Excursions of Glucose and Insulin in Nondiabetic Subjects

Selenoprotein P deficiency protects against immobilization-induced muscle atrophy by suppressing atrophy-related E3 ubiquitin ligases

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