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Targeted Metabolomics of Tissue and Plasma Identifies Biomarkers in Mice with NOTCH1-Dependent T-Cell Acute Lymphoblastic Leukemia

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6543

2024

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Insights on Metabolic Reprogramming and Its Therapeutic Potential in Acute Leukemia

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8738

2021

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Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia

Oncogene, 2020-10, Vol.39 (42), p.6544-6555

2020

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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Nature medicine, 2013-03, Vol.19 (3), p.368-371

2013

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Chemotactic Cues for NOTCH1-Dependent Leukemia

Frontiers in immunology, 2018-04, Vol.9, p.633-633

2018

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Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination

Leukemia, 2021-04, Vol.35 (4), p.984-1000

2021

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Responsiveness to Hedgehog Pathway Inhibitors in T-Cell Acute Lymphoblastic Leukemia Cells Is Highly Dependent on 5′AMP-Activated Kinase Inactivation

International journal of molecular sciences, 2021-06, Vol.22 (12), p.6384

2021

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WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

Haematologica (Roma), 2018-02, Vol.103 (2), p.266

2018

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Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (21), p.8947-8952

2007

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Implementation of Next Generation Sequencing-Based Liquid Biopsy for Clinical Molecular Diagnostics in Non-Small Cell Lung Cancer (NSCLC) Patients

Diagnostics (Basel), 2021-08, Vol.11 (8), p.1468

2021

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miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia

Cells (Basel, Switzerland), 2020-07, Vol.9 (7), p.1726

2020

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Absence of Biallelic TCRγ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia

Journal of clinical oncology, 2010-08, Vol.28 (24), p.3816-3823

2010

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Interruption of Tumor Dormancy by a Transient Angiogenic Burst within the Tumor Microenvironment

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (11), p.4216-4221

2006

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A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

Cells (Basel, Switzerland), 2018-10, Vol.7 (10), p.160

2018

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Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Nature medicine, 2015-10, Vol.21 (10), p.1182-1189

2015

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γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

Nature medicine, 2009-01, Vol.15 (1), p.50-58

2009

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Large and Dissimilar Repertoire of Melan-A/MART-1-Specific CTL in Metastatic Lesions and Blood of a Melanoma Patient

The Journal of immunology (1950), 2002-10, Vol.169 (7), p.4017-4024

2002

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ETV6 mutations in early immature human T cell leukemias

The Journal of experimental medicine, 2011-12, Vol.208 (13), p.2571-2579

2011

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Rapamycin-Mediated Enrichment of T Cells with Regulatory Activity in Stimulated CD4+ T Cell Cultures Is Not Due to the Selective Expansion of Naturally Occurring Regulatory T Cells but to the Induction of Regulatory Functions in Conventional CD4+ T Cells

The Journal of immunology (1950), 2006-07, Vol.177 (2), p.944-949

2006

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Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death

Oncotarget, 2016-07, Vol.7 (29), p.45715-45729

2016

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IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

The Journal of immunology (1950), 2003-01, Vol.170 (1), p.270-278

2003

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Targeting Nonclassical Oncogenes for Therapy in T-ALL

Cancer cell, 2012-04, Vol.21 (4), p.459-472

2012

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NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL

Blood, 2008-08, Vol.112 (3), p.733-740

2008

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Targeted Metabolomics of Tissue and Plasma Identifies Biomarkers in Mice with NOTCH1-Dependent T-Cell Acute Lymphoblastic Leukemia

Insights on Metabolic Reprogramming and Its Therapeutic Potential in Acute Leukemia

Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia

Chemotactic Cues for NOTCH1-Dependent Leukemia

Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination

Responsiveness to Hedgehog Pathway Inhibitors in T-Cell Acute Lymphoblastic Leukemia Cells Is Highly Dependent on 5′AMP-Activated Kinase Inactivation

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming

Implementation of Next Generation Sequencing-Based Liquid Biopsy for Clinical Molecular Diagnostics in Non-Small Cell Lung Cancer (NSCLC) Patients

miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia

Absence of Biallelic TCRγ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia

Interruption of Tumor Dormancy by a Transient Angiogenic Burst within the Tumor Microenvironment

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

Large and Dissimilar Repertoire of Melan-A/MART-1-Specific CTL in Metastatic Lesions and Blood of a Melanoma Patient

ETV6 mutations in early immature human T cell leukemias

Rapamycin-Mediated Enrichment of T Cells with Regulatory Activity in Stimulated CD4+ T Cell Cultures Is Not Due to the Selective Expansion of Naturally Occurring Regulatory T Cells but to the Induction of Regulatory Functions in Conventional CD4+ T Cells

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death

IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

Targeting Nonclassical Oncogenes for Therapy in T-ALL

NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL

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