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High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa

mBio, 2018-11, Vol.9 (6)

2018

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Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding Proteins

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5156

2019

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Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

Scientific reports, 2016-02, Vol.6 (1), p.20331-20331, Article 20331

2016

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Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications

Chembiochem : a European journal of chemical biology, 2018-05, Vol.19 (10), p.1088-1095

2018

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NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms

Biochimica et biophysica acta. Proteins and proteomics, 2019-07, Vol.1867 (7-8), p.663-676

2019

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Phosphorylation of Thr9 Affects the Folding Landscape of the N-Terminal Segment of Human AGT Enhancing Protein Aggregation of Disease-Causing Mutants

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8762

2022

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A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation

FEBS letters, 2022-01, Vol.596 (1), p.29-41

2022

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The lower limits for protein stability and foldability in primary hyperoxaluria type I

Biochimica et biophysica acta. Proteins and proteomics, 2014-12, Vol.1844 (12), p.2355-2365

2014

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Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Redox biology, 2021-10, Vol.46, p.102112-102112, Article 102112

2021

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The role of protein denaturation energetics and molecular chaperones in the aggregation and mistargeting of mutants causing primary hyperoxaluria type I

PloS one, 2013-08, Vol.8 (8), p.e71963-e71963

2013

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Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency

Biochemistry (Easton), 2013-02, Vol.52 (7), p.1160-1170

2013

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The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine-glyoxylate aminotransferase

Biochemical journal, 2014-09, Vol.462 (3), p.453-463

2014

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Molecular recognition of PTS-1 cargo proteins by Pex5p: implications for protein mistargeting in primary hyperoxaluria

Biomolecules (Basel, Switzerland), 2015-02, Vol.5 (1), p.121-141

2015

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Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses

Human molecular genetics, 2019-01, Vol.28 (1), p.1-15

2019

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Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution

Human molecular genetics, 2017-09, Vol.26 (18), p.3531-3544

2017

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The metastability of human UDP-galactose 4′-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding

Archives of biochemistry and biophysics, 2014-11, Vol.562, p.103-114

2014

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Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability

International journal of biological macromolecules, 2019-03, Vol.125, p.1275-1288

2019

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Evolutionary Divergent Suppressor Mutations in Conformational Diseases

Genes, 2018-07, Vol.9 (7), p.352

2018

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Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I

Advances in protein chemistry and structural biology, 2019, Vol.114, p.119-152

2019

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Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism

Biochimica et biophysica acta, 2016-09, Vol.1864 (9), p.1195-1205

2016

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Erratum: Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

Scientific reports, 2016-03, Vol.6 (1), p.21939-21939, Article 21939

2016

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The Role of Protein Denaturation Energetics and Molecular Chaperones in the Aggregation and Mistargeting of Mutants Causing Primary Hyperoxaluria Type I: e71963

PloS one, 2013-08, Vol.8 (8)

2013

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The Family of Two-Component Systems That Regulate Hydrocarbon Degradation Pathways

Cellular Ecophysiology of Microbe: Hydrocarbon and Lipid Interactions, p.201-220

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Desenlaces cardiovasculares en fibrilación auricular y COVID-19 grave en Latinoamérica: registro CARDIO COVID 19-20

REC: CardioClinics, 2024-01, Vol.59 (1), p.23-34

2024

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High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa

Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding Proteins

Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications

NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms

Phosphorylation of Thr9 Affects the Folding Landscape of the N-Terminal Segment of Human AGT Enhancing Protein Aggregation of Disease-Causing Mutants

A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation

The lower limits for protein stability and foldability in primary hyperoxaluria type I

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

The role of protein denaturation energetics and molecular chaperones in the aggregation and mistargeting of mutants causing primary hyperoxaluria type I

Structural and Energetic Basis of Protein Kinetic Destabilization in Human Phosphoglycerate Kinase 1 Deficiency

The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine-glyoxylate aminotransferase

Molecular recognition of PTS-1 cargo proteins by Pex5p: implications for protein mistargeting in primary hyperoxaluria

Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses

Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution

The metastability of human UDP-galactose 4′-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding

Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability

Evolutionary Divergent Suppressor Mutations in Conformational Diseases

Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I

Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism

Erratum: Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands

The Role of Protein Denaturation Energetics and Molecular Chaperones in the Aggregation and Mistargeting of Mutants Causing Primary Hyperoxaluria Type I: e71963

The Family of Two-Component Systems That Regulate Hydrocarbon Degradation Pathways

Desenlaces cardiovasculares en fibrilación auricular y COVID-19 grave en Latinoamérica: registro CARDIO COVID 19-20

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