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Therapeutic Targeting of the Soluble Guanylate Cyclase

Current medicinal chemistry, 2019-01, Vol.26 (15), p.2730-2747

2019

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Thioglycine and l-thiovaline: Biologically active H2S-donors

Bioorganic & medicinal chemistry, 2012-04, Vol.20 (8), p.2675-2678

2012

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Effects of Exposure to Tobacco Cigarette, Electronic Cigarette and Heated Tobacco Product on Adipocyte Survival and Differentiation In Vitro

Toxics (Basel), 2020-02, Vol.8 (1), p.9

2020

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Mapping of the sGC Stimulator BAY 41-2272 Binding Site on H-NOX Domain and Its Regulation by the Redox State of the Heme

Frontiers in cell and developmental biology, 2022-06, Vol.10, p.925457-925457

2022

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Design, synthesis and biological evaluation of new 3,4-dihydroquinoxalin-2(1H)-one derivatives as soluble guanylyl cyclase (sGC) activators

Heliyon, 2022-11, Vol.8 (11), p.e11438-e11438, Article e11438

2022

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Myostatin signaling through Smad2, Smad3 and Smad4 is regulated by the inhibitory Smad7 by a negative feedback mechanism

Cytokine (Philadelphia, Pa.), 2004-06, Vol.26 (6), p.262-272

2004

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PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns

American journal of physiology. Heart and circulatory physiology, 2009-02, Vol.296 (2), p.H442-H452

2009

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Replacement of heme by soluble guanylate cyclase (sGC) activators abolishes heme-nitric oxide/oxygen (H-NOX) domain structural plasticity

Current research in structural biology, 2021-01, Vol.3, p.324-336

2021

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Deciphering next-generation pharmacogenomics: an information technology perspective

Open biology, 2014-07, Vol.4 (7), p.140071

2014

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Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice

American journal of physiology. Lung cellular and molecular physiology, 2018-11, Vol.315 (5), p.L662-L672

2018

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Ascertainment and critical assessment of the views of the general public and healthcare professionals on nutrigenomics in Greece

Personalized medicine, 2012-03, Vol.9 (2), p.201-210

2012

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ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo

The Journal of pharmacology and experimental therapeutics, 2015-07, Vol.354 (1), p.79-87

2015

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Extending the translational potential of targeting NO/cGMP‐regulated pathways in the CVS

British journal of pharmacology, 2015-03, Vol.172 (6), p.1397-1414

2015

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Platelet-derived growth factor-D expression in developing and mature human kidneys

Kidney international, 2002-12, Vol.62 (6), p.2043-2054

2002

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Nurr1: RXRα heterodimer activation as monotherapy for Parkinson’s disease

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.3999-4004

2017

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Identification of new multi-substituted 1H-pyrazolo[3,4-c]pyridin-7(6H)-ones as soluble guanylyl cyclase (sGC) stimulators with vasoprotective and anti-inflammatory activities

Bioorganic chemistry, 2024-03, Vol.144, p.107170-107170, Article 107170

2024

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Role of cGMP in hydrogen sulfide signaling

Nitric oxide, 2015-04, Vol.46, p.7-13

2015

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Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review

British journal of pharmacology, 2024-06, Vol.181 (11), p.1553-1575

2024

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Oxidative stress induced by electronic nicotine delivery systems (ENDS): Focus on respiratory system

Current opinion in toxicology, 2019-02, Vol.13, p.81-89

2019

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The role of hydrogen sulfide in the adherence of endothelial cells in vitro

Nitric oxide, 2015-05, Vol.47, p.S59

2015

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PP112 - The role of hydrogen sulfide in the adherence of endothelial cells in vitro

Nitric oxide, 2015-05, Vol.47, p.S59-S59

2015

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Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation

American journal of respiratory cell and molecular biology, 2015-06, Vol.52 (6), p.762-771

2015

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Smooth Muscle Lineage Diversity in the Chick Embryo: Two Types of Aortic Smooth Muscle Cell Differ in Growth and Receptor-Mediated Transcriptional Responses to Transforming Growth Factor-β

Developmental biology, 1996-09, Vol.178 (2), p.430-445

1996

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Nurr1:RXRa heterodimer activation as monotherapy for Parkinson's disease

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.3999

2017

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PP65 - Selectivity of hydrogen sulfide toward cyclic nucleotide phosphodiesterases

Nitric oxide, 2015-05, Vol.47, p.S39-S39

2015

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Therapeutic Targeting of the Soluble Guanylate Cyclase

Thioglycine and l-thiovaline: Biologically active H2S-donors

Effects of Exposure to Tobacco Cigarette, Electronic Cigarette and Heated Tobacco Product on Adipocyte Survival and Differentiation In Vitro

Mapping of the sGC Stimulator BAY 41-2272 Binding Site on H-NOX Domain and Its Regulation by the Redox State of the Heme

Design, synthesis and biological evaluation of new 3,4-dihydroquinoxalin-2(1H)-one derivatives as soluble guanylyl cyclase (sGC) activators

Myostatin signaling through Smad2, Smad3 and Smad4 is regulated by the inhibitory Smad7 by a negative feedback mechanism

PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns

Replacement of heme by soluble guanylate cyclase (sGC) activators abolishes heme-nitric oxide/oxygen (H-NOX) domain structural plasticity

Deciphering next-generation pharmacogenomics: an information technology perspective

Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice

Ascertainment and critical assessment of the views of the general public and healthcare professionals on nutrigenomics in Greece

ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo

Extending the translational potential of targeting NO/cGMP‐regulated pathways in the CVS

Platelet-derived growth factor-D expression in developing and mature human kidneys

Nurr1: RXRα heterodimer activation as monotherapy for Parkinson’s disease

Identification of new multi-substituted 1H-pyrazolo[3,4-c]pyridin-7(6H)-ones as soluble guanylyl cyclase (sGC) stimulators with vasoprotective and anti-inflammatory activities

Role of cGMP in hydrogen sulfide signaling

Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: A year in review

Oxidative stress induced by electronic nicotine delivery systems (ENDS): Focus on respiratory system

The role of hydrogen sulfide in the adherence of endothelial cells in vitro

PP112 - The role of hydrogen sulfide in the adherence of endothelial cells in vitro

Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation

Smooth Muscle Lineage Diversity in the Chick Embryo: Two Types of Aortic Smooth Muscle Cell Differ in Growth and Receptor-Mediated Transcriptional Responses to Transforming Growth Factor-β

Nurr1:RXRa heterodimer activation as monotherapy for Parkinson's disease

PP65 - Selectivity of hydrogen sulfide toward cyclic nucleotide phosphodiesterases

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