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Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2388-2406

2005

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Cyclin-dependent kinase inhibitors for treating cancer

Medicinal research reviews, 2001-11, Vol.21 (6), p.487-498

Toogood, Peter L.

2001

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Ligand recognition by influenza virus. The binding of bivalent sialosides

The Journal of biological chemistry, 1991-12, Vol.266 (35), p.23660-23669

1991

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Progress toward the development of agents to modulate the cell cycle

Current Opinion in Chemical Biology, 2002-08, Vol.6 (4), p.472-478

Toogood, Peter L

2002

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Inhibition of protein synthesis by didemnin B is not sufficient to induce apoptosis in human mammary carcinoma (MCF7) cells

Biochemical pharmacology, 1999-09, Vol.58 (6), p.1067-1074

1999

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Inhibition of Protein Synthesis by Didemnins: Cell Potency and SAR

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4212-4218

2000

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Antifeedant effects of azadirachtin and structurally related compounds on lepidopterous larvae

Entomologia experimentalis et applicata, 1990-05, Vol.55 (2), p.149-160

1990

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Inhibition of Protein−Protein Association by Small Molecules: Approaches and Progress

Journal of medicinal chemistry, 2002-04, Vol.45 (8), p.1543-1558

Toogood, Peter L

2002

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Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts

Molecular cancer therapeutics, 2004-11, Vol.3 (11), p.1427-1438

2004

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Monovalent sialosides that bind tightly to influenza A virus

Journal of medicinal chemistry, 1991-10, Vol.34 (10), p.3138-3140

1991

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Inhibition of Protein Synthesis by Didemnin B: How EF-1α Mediates Inhibition of Translocation

Biochemistry (Easton), 2000-04, Vol.39 (15), p.4339-4346

2000

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Azadirachtin: structural requirements for reducing growth and increasing mortality in lepidopterous larvae

Entomologia experimentalis et applicata, 1990-05, Vol.55 (2), p.169-181

1990

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Mechanism of Protein Synthesis Inhibition by Didemnin B in Vitro

Biochemistry (Easton), 1995-07, Vol.34 (28), p.9177-9184

1995

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Behavioural and neurophysiological responses of Spodoptera littoralis to azadirachtin and a range of synthetic analogues

Entomologia experimentalis et applicata, 1995-10, Vol.77 (1), p.69-80

1995

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Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2371-2387

2005

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Model studies of lantibiotic biogenesis

Tetrahedron letters, 1993-12, Vol.34 (49), p.7833-7836

Toogood, Peter L.

1993

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Synthesis and biological evaluation of didemnin photoaffinity analogues

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1871-1874

2001

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Synthesis and biological activity of [Tic 5] didemnin B

Bioorganic & medicinal chemistry letters, 1998-12, Vol.8 (24), p.3653-3656

1998

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A Short and Efficient Synthesis of l-5,5,5,5‘,5‘,5‘-hexafluoroleucine from N-Cbz-l-Serine

Organic letters, 2002-11, Vol.4 (24), p.4281-4283

2002

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2-Aminoquinazoline inhibitors of cyclin-dependent kinases

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (17), p.3881-3885

2005

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Total Synthesis of Motuporin and 5-[l-Ala]-Motuporin

Journal of organic chemistry, 1999-04, Vol.64 (8), p.2711-2728

1999

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Sodium-directed selective cleavage of lactones: a method for structure determination of cyclodepsipeptides

International journal of mass spectrometry, 1999-03, Vol.182, p.289-298

1999

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Total synthesis of a keramamide

Chemical communications (Cambridge, England), 1999-06 (11), p.981-982

1999

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Inhibition of protein synthesis by didemnin B: how EF-1alpha mediates inhibition of translocation

Biochemistry (Easton), 2000-04, Vol.39 (15), p.4339

2000

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A new stereoselective route to (2 S, 3 S, 8 S, 9 S, 4 E, 6 E)-3-amino-9-methoxy-2, 6, 8-trimethyl-10-phenyldeca-4, 6-dienoic acid (Adda)

Tetrahedron letters, 1996-04, Vol.37 (14), p.2349-2352

1996

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Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6

Cyclin-dependent kinase inhibitors for treating cancer

Ligand recognition by influenza virus. The binding of bivalent sialosides

Progress toward the development of agents to modulate the cell cycle

Inhibition of protein synthesis by didemnin B is not sufficient to induce apoptosis in human mammary carcinoma (MCF7) cells

Inhibition of Protein Synthesis by Didemnins: Cell Potency and SAR

Antifeedant effects of azadirachtin and structurally related compounds on lepidopterous larvae

Inhibition of Protein−Protein Association by Small Molecules: Approaches and Progress

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts

Monovalent sialosides that bind tightly to influenza A virus

Inhibition of Protein Synthesis by Didemnin B: How EF-1α Mediates Inhibition of Translocation

Azadirachtin: structural requirements for reducing growth and increasing mortality in lepidopterous larvae

Mechanism of Protein Synthesis Inhibition by Didemnin B in Vitro

Behavioural and neurophysiological responses of Spodoptera littoralis to azadirachtin and a range of synthetic analogues

Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Model studies of lantibiotic biogenesis

Synthesis and biological evaluation of didemnin photoaffinity analogues

Synthesis and biological activity of [Tic 5] didemnin B

A Short and Efficient Synthesis of l-5,5,5,5‘,5‘,5‘-hexafluoroleucine from N-Cbz-l-Serine

2-Aminoquinazoline inhibitors of cyclin-dependent kinases

Total Synthesis of Motuporin and 5-[l-Ala]-Motuporin

Sodium-directed selective cleavage of lactones: a method for structure determination of cyclodepsipeptides

Total synthesis of a keramamide

Inhibition of protein synthesis by didemnin B: how EF-1alpha mediates inhibition of translocation

A new stereoselective route to (2 S, 3 S, 8 S, 9 S, 4 E, 6 E)-3-amino-9-methoxy-2, 6, 8-trimethyl-10-phenyldeca-4, 6-dienoic acid (Adda)

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