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Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice

Antimicrobial Agents and Chemotherapy, 2012-12, Vol.56 (12), p.6284-6290

2012

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The Isoniazid-NAD Adduct Is a Slow, Tight-Binding Inhibitor of InhA, the Mycobacterium tuberculosis Enoyl Reductase: Adduct Affinity and Drug Resistance

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (24), p.13881-13886

2003

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Vibrationally resolved photoabsorption spectroscopy of red fluorescent protein chromophore anions

Physical review letters, 2003-03, Vol.90 (11), p.118103, Article 118103

2003

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Inhibition of InhA, the Enoyl Reductase from Mycobacterium tuberculosis, by Triclosan and Isoniazid

Biochemistry (Easton), 2000-07, Vol.39 (26), p.7645-7650

2000

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Structural basis and mechanism of enoyl reductase inhibition by triclosan

Journal of molecular biology, 1999-07, Vol.290 (4), p.859-865

1999

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Synthesis of Crotonyl-OxyCoA: A Mechanistic Probe of the Reaction Catalyzed by Enoyl-CoA Hydratase

Journal of the American Chemical Society, 2001-01, Vol.123 (3), p.506-507

2001

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Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice

Antimicrobial agents and chemotherapy, 2013-01, Vol.57 (1), p.678-678

2013

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Involvement of Glycine 141 in Substrate Activation by Enoyl-CoA Hydratase

Biochemistry (Easton), 2001-02, Vol.40 (6), p.1725-1733

2001

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Probing the Ground State Structure of the Green Fluorescent Protein Chromophore Using Raman Spectroscopy

Biochemistry (Easton), 2000-04, Vol.39 (15), p.4423-4431

2000

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Active Site Heterogeneity in Dimethyl Sulfoxide Reductase from Rhodobacter capsulatus Revealed by Raman Spectroscopy

Biochemistry (Easton), 2001-01, Vol.40 (2), p.440-448

2001

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Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis

Biochemistry (Easton), 1999-10, Vol.38 (41), p.13623-13634

1999

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Medium-Chain Acyl-Coenzyme A Dehydrogenase Bound to a Product Analogue, Hexadienoyl-Coenzyme A: Effects on Reduction Potential, pK a, and Polarization

Biochemistry (Easton), 2000-11, Vol.39 (45), p.13982-13992

2000

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Forces, bond lengths, and reactivity: fundamental insight into the mechanism of enzyme catalysis

Biochemistry (Easton), 1992-09, Vol.31 (38), p.9122-9125

1992

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Transient IR study of Blue Light Sensing Proteins

EPJ Web of conferences, 2013-01, Vol.41, p.7009-np

2013

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H-Bonding in Alcohols Is Reflected in the Cα−H Bond Strength: Variation of C−D Vibrational Frequency and Fractionation Factor

Journal of the American Chemical Society, 2000-11, Vol.122 (47), p.11660-11669

2000

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Stable Analogues of OSB-AMP: Potent Inhibitors of MenE, the o-Succinylbenzoate-CoA Synthetase from Bacterial Menaquinone Biosynthesis

Chembiochem : a European journal of chemical biology, 2012-01, Vol.13 (1), p.129-136

2012

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Length of the acyl carbonyl bond in acyl-serine proteases correlates with reactivity

Biochemistry (Easton), 1990-12, Vol.29 (48), p.10723-10727

1990

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Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (17), p.5489-5495

2015

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Structural and Functional Studies of Fatty Acyl Adenylate Ligases from E. coli and L. pneumophila

Journal of molecular biology, 2011-02, Vol.406 (2), p.313-324

2011

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Structure and Mechanism of MbtI, the Salicylate Synthase from Mycobacterium tuberculosis

Biochemistry (Easton), 2007-01, Vol.46 (4), p.954-964

2007

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Role of Glutamate 144 and Glutamate 164 in the Catalytic Mechanism of Enoyl-CoA Hydratase

Biochemistry (Easton), 1999-07, Vol.38 (29), p.9508-9516

1999

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Effect of Mutagenesis on the Stereochemistry of Enoyl-CoA Hydratase

Biochemistry (Easton), 2002-10, Vol.41 (42), p.12883-12890

2002

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Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei

Journal of antimicrobial chemotherapy, 2011-03, Vol.66 (3), p.564-573

2011

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Another brick in the wall

Nature structural & molecular biology, 2000-02, Vol.7 (2), p.94-96

Tonge, Peter J

2000

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Lysine 190 Is the Catalytic Base in MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia coli: Implications for an Enzyme Family

Biochemistry (Easton), 2007-01, Vol.46 (4), p.946-953

2007

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Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice

The Isoniazid-NAD Adduct Is a Slow, Tight-Binding Inhibitor of InhA, the Mycobacterium tuberculosis Enoyl Reductase: Adduct Affinity and Drug Resistance

Vibrationally resolved photoabsorption spectroscopy of red fluorescent protein chromophore anions

Inhibition of InhA, the Enoyl Reductase from Mycobacterium tuberculosis, by Triclosan and Isoniazid

Structural basis and mechanism of enoyl reductase inhibition by triclosan

Synthesis of Crotonyl-OxyCoA: A Mechanistic Probe of the Reaction Catalyzed by Enoyl-CoA Hydratase

Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice

Involvement of Glycine 141 in Substrate Activation by Enoyl-CoA Hydratase

Probing the Ground State Structure of the Green Fluorescent Protein Chromophore Using Raman Spectroscopy

Active Site Heterogeneity in Dimethyl Sulfoxide Reductase from Rhodobacter capsulatus Revealed by Raman Spectroscopy

Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis

Medium-Chain Acyl-Coenzyme A Dehydrogenase Bound to a Product Analogue, Hexadienoyl-Coenzyme A: Effects on Reduction Potential, pK a, and Polarization

Forces, bond lengths, and reactivity: fundamental insight into the mechanism of enzyme catalysis

Transient IR study of Blue Light Sensing Proteins

H-Bonding in Alcohols Is Reflected in the Cα−H Bond Strength: Variation of C−D Vibrational Frequency and Fractionation Factor

Stable Analogues of OSB-AMP: Potent Inhibitors of MenE, the o-Succinylbenzoate-CoA Synthetase from Bacterial Menaquinone Biosynthesis

Length of the acyl carbonyl bond in acyl-serine proteases correlates with reactivity

Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A

Structural and Functional Studies of Fatty Acyl Adenylate Ligases from E. coli and L. pneumophila

Structure and Mechanism of MbtI, the Salicylate Synthase from Mycobacterium tuberculosis

Role of Glutamate 144 and Glutamate 164 in the Catalytic Mechanism of Enoyl-CoA Hydratase

Effect of Mutagenesis on the Stereochemistry of Enoyl-CoA Hydratase

Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei

Another brick in the wall

Lysine 190 Is the Catalytic Base in MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia coli: Implications for an Enzyme Family

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