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Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL

Cancer research (Chicago, Ill.), 2009-09, Vol.69 (17), p.6871-6878

2009

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Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma

Cell reports (Cambridge), 2013-09, Vol.4 (6), p.1090-1099

2013

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Oxidative stress and DNA damage resulting from welding fumes exposure among professional welders: A systematic review and meta-analysis

Environmental research, 2022-11, Vol.214, p.114152-114152, Article 114152

2022

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Developing non-response weights to account for attrition-related bias in a longitudinal pregnancy cohort

BMC medical research methodology, 2023-12, Vol.23 (1), p.295-295, Article 295

2023

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Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.909-920

2012

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Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

Cancer research (Chicago, Ill.), 2006-02, Vol.66 (3), p.1630-1639

2006

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The effectiveness of booster seat use in motor vehicle collisions

Accident analysis and prevention, 2021-09, Vol.159, p.106296-106296, Article 106296

2021

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Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

Molecular cancer therapeutics, 2007-07, Vol.6 (7), p.2012-2021

2007

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You exhaust me! Air pollution exposure near schools during pick-up and drop-off times

Paediatrics & child health, 2023-08, Vol.28 (6), p.275-277

2023

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Identifying modifiable factors related to novice adolescent driver fault in motor vehicle collisions

Traffic injury prevention, 2021-08, Vol.22 (6), p.437-442

2021

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Process intensification for lentiviral vector manufacturing using tangential flow depth filtration

Molecular therapy. Methods & clinical development, 2023-06, Vol.29, p.93-107

2023

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The Relationship of Urban Form on Children and Adolescent Health Outcomes: A Scoping Review of Canadian Evidence

International journal of environmental research and public health, 2021-04, Vol.18 (8), p.4180

2021

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Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells

Molecular cancer therapeutics, 2011-03, Vol.10 (3), p.518-530

2011

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A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): Relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

Cancer research (Chicago, Ill.), 2004-09, Vol.64 (18), p.6652-6659

2004

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Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles

Molecular cancer therapeutics, 2007-05, Vol.6 (5), p.1629-1640

2007

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In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1

Molecular cancer therapeutics, 2007-02, Vol.6 (2), p.450-459

2007

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Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Cancer research (Chicago, Ill.), 2008-04, Vol.68 (7), p.2366-2374

2008

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Lapatinib: functional genomics study leads to insights into mechanism of action

Molecular cancer therapeutics, 2011-11, Vol.10 (11), p.2025-2025

Gilmer, Tona M

2011

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The discovery of lapatinib (GW572016)

Molecular cancer therapeutics, 2011-11, Vol.10 (11), p.2019-2019

2011

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Design and development of a novel nuclear magnetic resonance detection for the gas phase ions by magnetic resonance acceleration technique

Review of scientific instruments, 2012-08, Vol.83 (8), p.085106-085106

2012

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Impact of Common Epidermal Growth Factor Receptor and HER2 Variants on Receptor Activity and Inhibition by Lapatinib

Cancer research (Chicago, Ill.), 2008-01, Vol.68 (2), p.571-579

2008

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The Effects of the Novel, Reversible Epidermal Growth Factor Receptor/ErbB-2 Tyrosine Kinase Inhibitor, GW2016, on the Growth of Human Normal and Tumor-derived Cell Lines in Vitro and in Vivo

Molecular cancer therapeutics, 2001-12, Vol.1 (2), p.85-94

2001

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Identifying motorist characteristics associated with youth bicycle-motor vehicle collisions

Traffic injury prevention, 2019-10, Vol.20 (7), p.744-748

2019

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Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data

Clinical cancer research, 2008-12, Vol.14 (23), p.7900-7908

2008

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Preparation of cold ions in strong magnetic field and its application to gas-phase NMR spectroscopy

Hyperfine interactions, 2015-11, Vol.236 (1-3), p.9-18

2015

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Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL

Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma

Oxidative stress and DNA damage resulting from welding fumes exposure among professional welders: A systematic review and meta-analysis

Developing non-response weights to account for attrition-related bias in a longitudinal pregnancy cohort

Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations

Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells

The effectiveness of booster seat use in motor vehicle collisions

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity

You exhaust me! Air pollution exposure near schools during pick-up and drop-off times

Identifying modifiable factors related to novice adolescent driver fault in motor vehicle collisions

Process intensification for lentiviral vector manufacturing using tangential flow depth filtration

The Relationship of Urban Form on Children and Adolescent Health Outcomes: A Scoping Review of Canadian Evidence

Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells

A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): Relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles

In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Lapatinib: functional genomics study leads to insights into mechanism of action

The discovery of lapatinib (GW572016)

Design and development of a novel nuclear magnetic resonance detection for the gas phase ions by magnetic resonance acceleration technique

Impact of Common Epidermal Growth Factor Receptor and HER2 Variants on Receptor Activity and Inhibition by Lapatinib

The Effects of the Novel, Reversible Epidermal Growth Factor Receptor/ErbB-2 Tyrosine Kinase Inhibitor, GW2016, on the Growth of Human Normal and Tumor-derived Cell Lines in Vitro and in Vivo

Identifying motorist characteristics associated with youth bicycle-motor vehicle collisions

Evaluation of Lapatinib and Topotecan Combination Therapy: Tissue Culture, Murine Xenograft, and Phase I Clinical Trial Data

Preparation of cold ions in strong magnetic field and its application to gas-phase NMR spectroscopy

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