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Development, Characterization and Potential Applications of a Multicellular Spheroidal Human Blood–Brain Barrier Model Integrating Three Conditionally Immortalized Cell Lines

Biological and Pharmaceutical Bulletin, 2021/07/01, Vol.44(7), pp.984-991

2021

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Functional Expression of Organic Ion Transporters in Astrocytes and Their Potential as a Drug Target in the Treatment of Central Nervous System Diseases

Biological and Pharmaceutical Bulletin, 2017/08/01, Vol.40(8), pp.1153-1160

2017

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Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

Scientific reports, 2020-01, Vol.10 (1), p.1292-1292, Article 1292

2020

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Quaternization of high molecular weight chitosan for increasing intestinal drug absorption using Caco-2 cells as an in vitro intestinal model

Scientific reports, 2023-05, Vol.13 (1), p.7904-7904, Article 7904

2023

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Interstitial flow regulates in vitro three-dimensional self-organized brain micro-vessels

Biochemical and biophysical research communications, 2020-12, Vol.533 (3), p.600-606

2020

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Calculation of Human Melatonin Partial Metabolic Clearance in Healthy Adult Volunteers for Investigation of a Novel in Vivo CYP1A2 Phenotyping Method: A Pilot Study

Biological and Pharmaceutical Bulletin, 2023/05/01, Vol.46(5), pp.736-740

2023

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An in vitro self-organized three-dimensional model of the blood-brain barrier microvasculature

Biomedical materials (Bristol), 2021-01, Vol.16 (1), p.015006

2021

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In Vivo Introduction of mRNA Encapsulated in Lipid Nanoparticles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration

Molecular pharmaceutics, 2018-05, Vol.15 (5), p.2060-2067

2018

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Quantification of fluticasone propionate in human plasma by LC–MS/MS and its application in the pharmacokinetic study of nasal spray at clinical doses

Drug metabolism and pharmacokinetics, 2024-02, Vol.54, p.100541-100541, Article 100541

2024

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Development and Validation of an LC–MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin

Chemical and Pharmaceutical Bulletin, 2022/05/01, Vol.70(5), pp.375-382

2022

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Establishment and characterization of a new conditionally immortalized human astrocyte cell line

Journal of neurochemistry, 2016-01, Vol.136 (1), p.92-105

2016

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Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies

Biological and Pharmaceutical Bulletin, 2018/05/01, Vol.41(5), pp.697-706

2018

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Different Response Profiles of Gastrointestinal Cancer Cells to an L-Type Amino Acid Transporter Inhibitor, JPH203

Anticancer research, 2019-01, Vol.39 (1), p.159-165

2019

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siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles

Journal of controlled release, 2023-01, Vol.353, p.125-133

2023

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Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma

Scientific reports, 2019-11, Vol.9 (1), p.16776-10, Article 16776

2019

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In Vitro-In Vivo Correlation of Blood–Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans

Pharmaceutical research, 2022-07, Vol.39 (7), p.1575-1586

2022

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Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.18614-18624

2020

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A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies

Molecular pharmaceutics, 2019-11, Vol.16 (11), p.4461-4471

2019

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Quantification of Melatonin, Caffeine, and Paraxanthine in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry

Chromatographia, 2024-03, Vol.87 (3), p.167-174

2024

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Development of a New Conditionally Immortalized Human Liver Sinusoidal Endothelial Cells

Biological and Pharmaceutical Bulletin, 2018/03/01, Vol.41(3), pp.440-444

2018

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Characterization of an L-Carnitine Transport System in Murine Photoreceptor Cell Line

Biological and Pharmaceutical Bulletin, 2017/12/01, Vol.40(12), pp.2110-2116

2017

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Transferrin receptor-targeting property of pabinafusp alfa facilitates its uptake by various types of human brain-derived cells in vitro

Frontiers in Drug Delivery, 2023-07, Vol.3

2023

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Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert

APL bioengineering, 2022-03, Vol.6 (1), p.016103-016103-9

2022

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Soluble CD40 ligand disrupts the blood–brain barrier and exacerbates inflammation in experimental autoimmune encephalomyelitis

Journal of neuroimmunology, 2018-03, Vol.316, p.117-120

2018

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Cancer-type Organic Anion Transporting Polypeptide 1B3: Current Knowledge of the Gene Structure, Expression Profile, Functional Implications and Future Perspectives

Current drug metabolism, 2015-10, Vol.16 (6), p.474

2015

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Development, Characterization and Potential Applications of a Multicellular Spheroidal Human Blood–Brain Barrier Model Integrating Three Conditionally Immortalized Cell Lines

Functional Expression of Organic Ion Transporters in Astrocytes and Their Potential as a Drug Target in the Treatment of Central Nervous System Diseases

Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma

Quaternization of high molecular weight chitosan for increasing intestinal drug absorption using Caco-2 cells as an in vitro intestinal model

Interstitial flow regulates in vitro three-dimensional self-organized brain micro-vessels

Calculation of Human Melatonin Partial Metabolic Clearance in Healthy Adult Volunteers for Investigation of a Novel in Vivo CYP1A2 Phenotyping Method: A Pilot Study

An in vitro self-organized three-dimensional model of the blood-brain barrier microvasculature

In Vivo Introduction of mRNA Encapsulated in Lipid Nanoparticles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration

Quantification of fluticasone propionate in human plasma by LC–MS/MS and its application in the pharmacokinetic study of nasal spray at clinical doses

Development and Validation of an LC–MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin

Establishment and characterization of a new conditionally immortalized human astrocyte cell line

Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies

Different Response Profiles of Gastrointestinal Cancer Cells to an L-Type Amino Acid Transporter Inhibitor, JPH203

siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles

Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma

In Vitro-In Vivo Correlation of Blood–Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans

Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure

A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies

Quantification of Melatonin, Caffeine, and Paraxanthine in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry

Development of a New Conditionally Immortalized Human Liver Sinusoidal Endothelial Cells

Characterization of an L-Carnitine Transport System in Murine Photoreceptor Cell Line

Transferrin receptor-targeting property of pabinafusp alfa facilitates its uptake by various types of human brain-derived cells in vitro

Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert

Soluble CD40 ligand disrupts the blood–brain barrier and exacerbates inflammation in experimental autoimmune encephalomyelitis

Cancer-type Organic Anion Transporting Polypeptide 1B3: Current Knowledge of the Gene Structure, Expression Profile, Functional Implications and Future Perspectives

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