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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Nature (London), 2011-09, Vol.477 (7363), p.225-228

2011

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The effects of mutational processes and selection on driver mutations across cancer types

Nature communications, 2018-05, Vol.9 (1), p.1857-10, Article 1857

2018

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Mitochondrial tumour suppressors: a genetic and biochemical update

Nature reviews. Cancer, 2005-11, Vol.5 (11), p.857-866

2005

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Chromosomal Instability Confers Intrinsic Multidrug Resistance

Cancer research (Chicago, Ill.), 2011-03, Vol.71 (5), p.1858-1870

2011

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Prognostic significance of POLE proofreading mutations in endometrial cancer

JNCI : Journal of the National Cancer Institute, 2015-01, Vol.107 (1), p.402

2015

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Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer

Journal of clinical oncology, 2013-12, Vol.31 (34), p.4297-4305

2013

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Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

Cancer research (Chicago, Ill.), 2014-06, Vol.74 (12), p.3238-3247

2014

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Replication stress links structural and numerical cancer chromosomal instability

Nature (London), 2013-02, Vol.494 (7438), p.492-496

2013

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Measuring single cell divisions in human tissues from multi-region sequencing data

Nature communications, 2020-02, Vol.11 (1), p.1035-1035, Article 1035

2020

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The importance of p53 pathway genetics in inherited and somatic cancer genomes

Nature reviews. Cancer, 2016-04, Vol.16 (4), p.251

2016

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Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12722

2023

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Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

British journal of cancer, 2021-03, Vol.124 (7), p.1330-1338

2021

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Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank

British journal of cancer, 2022-03, Vol.126 (5), p.822-830

2022

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KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

Clinical cancer research, 2011-03, Vol.17 (5), p.1122-1130

2011

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Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

Nature genetics, 2012-04, Vol.44 (4), p.420-425

2012

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PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis

Cancer research (Chicago, Ill.), 2011-05, Vol.71 (10), p.3709-3719

2011

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A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

Cell, 2013-10, Vol.155 (2), p.410-422

2013

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Author Correction: The effects of mutational processes and selection on driver mutations across cancer types

Nature communications, 2020-04, Vol.11 (1), p.1959-1959, Article 1959

2020

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Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study

JNCI : Journal of the National Cancer Institute, 2011-03, Vol.103 (5), p.425-435

2011

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Adjuvant Treatment for POLE Proofreading Domain-Mutant Cancers: Sensitivity to Radiotherapy, Chemotherapy, and Nucleoside Analogues

Clinical cancer research, 2018-07, Vol.24 (13), p.3197-3203

2018

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The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency

BMC medical genetics, 2008-03, Vol.9 (1), p.20-20, Article 20

2008

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A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

Gut, 2013-01, Vol.62 (1), p.83-93

2013

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Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis

Cell reports (Cambridge), 2018-03, Vol.22 (12), p.3107-3114

2018

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Genomic instability - the engine of tumorigenesis?

Nature reviews. Cancer, 2003-09, Vol.3 (9), p.701-708

2003

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

The effects of mutational processes and selection on driver mutations across cancer types

Mitochondrial tumour suppressors: a genetic and biochemical update

Chromosomal Instability Confers Intrinsic Multidrug Resistance

Prognostic significance of POLE proofreading mutations in endometrial cancer

Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

Replication stress links structural and numerical cancer chromosomal instability

Measuring single cell divisions in human tissues from multi-region sequencing data

The importance of p53 pathway genetics in inherited and somatic cancer genomes

Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types

Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status

PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

Author Correction: The effects of mutational processes and selection on driver mutations across cancer types

Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study

Adjuvant Treatment for POLE Proofreading Domain-Mutant Cancers: Sensitivity to Radiotherapy, Chemotherapy, and Nucleoside Analogues

The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis

Genomic instability - the engine of tumorigenesis?

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