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The Mutation Rate and Cancer

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (25), p.14800-14803

1996

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Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

British journal of cancer, 2008-12, Vol.99 (12), p.2088-2093

2008

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TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

Gut, 2012-02, Vol.61 (2), p.248-254

2012

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Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia

Leukemia, 2012-10, Vol.26 (10), p.2212-2215

2012

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comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence

The Journal of pathology, 2008-04, Vol.214 (5), p.533-544

2008

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APC and the three-hit hypothesis

Oncogene, 2009-01, Vol.28 (1), p.146-155

2009

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β -Catenin Mutations in Cell Lines Established from Human Colorectal Cancers

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (19), p.10330-10334

1997

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Location in the large bowel influences the APC mutations observed in FAP adenomas

Familial cancer, 2010-09, Vol.9 (3), p.389-393

2010

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Molecular classification and genetic pathways in hyperplastic polyposis syndrome

The Journal of pathology, 2007-08, Vol.212 (4), p.378-385

2007

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mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours

The Journal of pathology, 2008-12, Vol.216 (4), p.408-417

2008

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Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation

Gut, 2006-10, Vol.55 (10), p.1440-1448

2006

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Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

Oncogene, 2013-09, Vol.32 (39), p.4675-4682

2013

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Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

Nature communications, 2014-04, Vol.5 (1), p.3756-3756, Article 3756

2014

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Whole-Gene APC Deletions Cause Classical Familial Adenomatous Polyposis, but not Attenuated Polyposis or "Multiple" Colorectal Adenomas

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2954-2958

2002

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Molecular characteristics of serrated adenomas of the colorectum

Gut, 2002-08, Vol.51 (2), p.200-206

2002

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An Ancestral Ashkenazi Haplotype at the HMPS/CRAC1 Locus on 15q13–q14 Is Associated with Hereditary Mixed Polyposis Syndrome

American journal of human genetics, 2003-05, Vol.72 (5), p.1261-1267

2003

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Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate

The Journal of pathology, 2008-06, Vol.215 (2), p.204-210

2008

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Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH MUTYH mutations

British journal of cancer, 2007-06, Vol.96 (11), p.1729-1734

2007

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Analysis of Chromosomal Instability in Human Colorectal Adenomas with Two Mutational Hits at APC

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (26), p.16910-16915

2002

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Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas

The Journal of pathology, 2007-11, Vol.213 (3), p.249-256

2007

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Polyclonal Origin of Colonic Adenomas in an XO/XY Patient with FAP

Science (American Association for the Advancement of Science), 1996-05, Vol.272 (5265), p.1187-1190

1996

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Mechanisms of Inactivation of Mismatch Repair Genes in Human Colorectal Cancer Cell Lines: The Predominant Role of hMLH1

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (18), p.10296-10301

1999

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A study of genomic instability in early preneoplastic colonic lesions

Oncogene, 2013-11, Vol.32 (46), p.5333-5337

2013

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The role of cell proliferation and crypt fission in adenoma aggressiveness: a comparison of ileoanal pouch and rectal adenomas in familial adenomatous polyposis

Colorectal disease, 2011-04, Vol.13 (4), p.387-392

2011

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APC Mutations in Sporadic Colorectal Tumors: A Mutational "Hotspot" and Interdependence of the "Two Hits"

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (7), p.3352-3357

2000

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The Mutation Rate and Cancer

Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

Common genetic variation contributes significantly to the risk of childhood B-cell precursor acute lymphoblastic leukemia

comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence

APC and the three-hit hypothesis

β -Catenin Mutations in Cell Lines Established from Human Colorectal Cancers

Location in the large bowel influences the APC mutations observed in FAP adenomas

Molecular classification and genetic pathways in hyperplastic polyposis syndrome

mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours

Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

Whole-Gene APC Deletions Cause Classical Familial Adenomatous Polyposis, but not Attenuated Polyposis or "Multiple" Colorectal Adenomas

Molecular characteristics of serrated adenomas of the colorectum

An Ancestral Ashkenazi Haplotype at the HMPS/CRAC1 Locus on 15q13–q14 Is Associated with Hereditary Mixed Polyposis Syndrome

Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate

Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH MUTYH mutations

Analysis of Chromosomal Instability in Human Colorectal Adenomas with Two Mutational Hits at APC

Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas

Polyclonal Origin of Colonic Adenomas in an XO/XY Patient with FAP

Mechanisms of Inactivation of Mismatch Repair Genes in Human Colorectal Cancer Cell Lines: The Predominant Role of hMLH1

A study of genomic instability in early preneoplastic colonic lesions

The role of cell proliferation and crypt fission in adenoma aggressiveness: a comparison of ileoanal pouch and rectal adenomas in familial adenomatous polyposis

APC Mutations in Sporadic Colorectal Tumors: A Mutational "Hotspot" and Interdependence of the "Two Hits"

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