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Protein-based antigen presentation platforms for nanoparticle vaccines

npj vaccines, 2021-05, Vol.6 (1), p.70-70, Article 70

2021

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Getting in: The structural biology of malaria invasion

PLoS pathogens, 2019-09, Vol.15 (9), p.e1007943-e1007943

2019

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Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design

Scientific reports, 2022-11, Vol.12 (1), p.19556-19556, Article 19556

2022

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Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii

PLoS genetics, 2015-08, Vol.11 (8), p.e1005434-e1005434

2015

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Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

Nature structural & molecular biology, 2011-08, Vol.18 (8), p.908-914

2011

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Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Nature communications, 2022-10, Vol.13 (1), p.5888-5888, Article 5888

2022

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Red blood cell invasion by Plasmodium vivax: structural basis for DBP engagement of DARC

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003869-e1003869

2014

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Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Nature communications, 2023-09, Vol.14 (1), p.5345-5345, Article 5345

2023

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Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102241-102241, Article 102241

2022

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Exploring the “minimal” structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering

Blood, 2019-04, Vol.133 (17), p.1909-1918

2019

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Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion

PLoS pathogens, 2014-06, Vol.10 (6), p.e1004120-e1004120

2014

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Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria

Nature communications, 2024-08, Vol.15 (1), p.7487-14, Article 7487

2024

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Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

Communications biology, 2020-05, Vol.3 (1), p.241, Article 241

2020

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Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding

Scientific reports, 2021-03, Vol.11 (1), p.5930-5930, Article 5930

2021

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Purified Argonaute2 and an siRNA form recombinant human RISC

Nature structural & molecular biology, 2005-04, Vol.12 (4), p.340-349

2005

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Naturally acquired antibodies against Plasmodium vivax pre-erythrocytic stage vaccine antigens inhibit sporozoite invasion of human hepatocytes in vitro

Scientific reports, 2024-01, Vol.14 (1), p.1260-1260, Article 1260

2024

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Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Cell reports (Cambridge), 2023-03, Vol.42 (3), p.112266, Article 112266

2023

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Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum

Cell, 2005-07, Vol.122 (2), p.183-193

2005

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Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

Nature microbiology, 2021-03, Vol.6 (3), p.380-391

2021

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Structural and functional basis for inhibition of erythrocyte invasion by antibodies that target Plasmodium falciparum EBA-175

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003390-e1003390

2013

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Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion

The Journal of biological chemistry, 2012-10, Vol.287 (44), p.36830-36836

2012

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Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design

PLoS neglected tropical diseases, 2015-03, Vol.9 (3), p.e0003644-e0003644

2015

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Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

eLife, 2016-12, Vol.5

2016

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Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine

npj vaccines, 2023-02, Vol.8 (1), p.20-20, Article 20

2023

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Critical glycosylated residues in exon three of erythrocyte glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity

mBio, 2014-09, Vol.5 (5), p.e01606-e01614

2014

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Protein-based antigen presentation platforms for nanoparticle vaccines

Getting in: The structural biology of malaria invasion

Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii

Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Red blood cell invasion by Plasmodium vivax: structural basis for DBP engagement of DARC

Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration

Exploring the “minimal” structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering

Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion

Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding

Purified Argonaute2 and an siRNA form recombinant human RISC

Naturally acquired antibodies against Plasmodium vivax pre-erythrocytic stage vaccine antigens inhibit sporozoite invasion of human hepatocytes in vitro

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

Structural and functional basis for inhibition of erythrocyte invasion by antibodies that target Plasmodium falciparum EBA-175

Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion

Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine

Critical glycosylated residues in exon three of erythrocyte glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity

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