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IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex

Nature communications, 2020-09, Vol.11 (1), p.1-13, Article 4775

2020

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EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation

PloS one, 2019-09, Vol.14 (9), p.e0221048-e0221048

2019

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Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (9), p.2206-2211

2017

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Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing

Journal of virology, 2019-11, Vol.93 (21)

2019

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Enterovirus A71 Vaccines

Vaccines (Basel), 2021-02, Vol.9 (3), p.199

2021

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Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex

Nature communications, 2023-04, Vol.14 (1), p.2304-2304, Article 2304

2023

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The Repurposing of Cellular Proteins during Enterovirus A71 Infection

Viruses, 2023-12, Vol.16 (1), p.75

2023

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Regio-Selective Chemical-Enzymatic Synthesis of Pyrimidine Nucleotides Facilitates RNA Structure and Dynamics Studies

Chembiochem : a European journal of chemical biology, 2014-07, Vol.15 (11), p.1573-1577

2014

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Direct Determination of Thiol pKa by Isothermal Titration Microcalorimetry

Journal of the American Chemical Society, 2004-09, Vol.126 (34), p.10508-10509

2004

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Regulatory Mechanisms through RNA Conformational Switching and Dynamics

Journal of molecular biology, 2022-09, Vol.434 (18), p.167794-167794, Article 167794

2022

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HnRNP A1/A2 Proteins Assemble onto 7SK snRNA via Context Dependent Interactions

Journal of molecular biology, 2021-04, Vol.433 (9), p.166885-166885, Article 166885

2021

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Idiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function

Seminars in cell & developmental biology, 2019-02, Vol.86, p.150-161

2019

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Thermodynamic stability of hnRNP A1 low complexity domain revealed by high‐pressure NMR

Proteins, structure, function, and bioinformatics, 2021-07, Vol.89 (7), p.781-791

2021

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Integrated approaches to reveal mechanisms by which RNA viruses reprogram the cellular environment

Methods (San Diego, Calif.), 2020-11, Vol.183, p.50-56

2020

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HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation

Journal of molecular biology, 2017-09, Vol.429 (19), p.2841-2858

2017

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A Structurally Conserved RNA Element within SARS-CoV-2 ORF1a RNA and S mRNA Regulates Translation in Response to Viral S Protein-Induced Signaling in Human Lung Cells

Journal of virology, 2022-01, Vol.96 (2), p.e0167821

2022

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Encoded Conformational Dynamics of the HIV Splice Site A3 Regulatory Locus: Implications for Differential Binding of hnRNP Splicing Auxiliary Factors

Journal of molecular biology, 2022-09, Vol.434 (18), p.167728-167728, Article 167728

2022

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Differential Binding between PatS C-Terminal Peptide Fragments and HetR from Anabaena sp. PCC 7120

Biochemistry (Easton), 2012-03, Vol.51 (12), p.2436-2442

2012

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Editorial for “Methods to characterize virus small RNAs and RNA structures”

Methods (San Diego, Calif.), 2020-11, Vol.183, p.1-3

2020

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The Discovery of Antivirals and Targets for SARS‐CoV‐2 and EV‐A71

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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The 5'UTR of HCoV-OC43 adopts a topologically constrained structure to intrinsically repress translation

The Journal of biological chemistry, 2023-04, Vol.299 (4), p.103028-103028

2023

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Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Biosensors & bioelectronics, 2018-10, Vol.117, p.60-67

2018

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Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon

Nucleic acids research, 2017-12, Vol.45 (22), p.12987-13003

2017

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Nanoparticle based simple electrochemical biosensor platform for profiling of protein-nucleic acid interactions

Talanta (Oxford), 2019-04, Vol.195, p.46-54

2019

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R‑BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures

ACS chemical biology, 2022-06, Vol.17 (6), p.1556-1566

2022

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IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex

EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation

Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution

Genome-Wide Analysis of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Binding to HIV-1 RNA Reveals a Key Role for hnRNP H1 in Alternative Viral mRNA Splicing

Enterovirus A71 Vaccines

Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex

The Repurposing of Cellular Proteins during Enterovirus A71 Infection

Regio-Selective Chemical-Enzymatic Synthesis of Pyrimidine Nucleotides Facilitates RNA Structure and Dynamics Studies

Direct Determination of Thiol pKa by Isothermal Titration Microcalorimetry

Regulatory Mechanisms through RNA Conformational Switching and Dynamics

HnRNP A1/A2 Proteins Assemble onto 7SK snRNA via Context Dependent Interactions

Idiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function

Thermodynamic stability of hnRNP A1 low complexity domain revealed by high‐pressure NMR

Integrated approaches to reveal mechanisms by which RNA viruses reprogram the cellular environment

HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation

A Structurally Conserved RNA Element within SARS-CoV-2 ORF1a RNA and S mRNA Regulates Translation in Response to Viral S Protein-Induced Signaling in Human Lung Cells

Encoded Conformational Dynamics of the HIV Splice Site A3 Regulatory Locus: Implications for Differential Binding of hnRNP Splicing Auxiliary Factors

Differential Binding between PatS C-Terminal Peptide Fragments and HetR from Anabaena sp. PCC 7120

Editorial for “Methods to characterize virus small RNAs and RNA structures”

The Discovery of Antivirals and Targets for SARS‐CoV‐2 and EV‐A71

The 5'UTR of HCoV-OC43 adopts a topologically constrained structure to intrinsically repress translation

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon

Nanoparticle based simple electrochemical biosensor platform for profiling of protein-nucleic acid interactions

R‑BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures

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