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Targeting DNA Minor Groove by Hybrid Molecules as Anticancer Agents

Current medicinal chemistry, 2017-08, Vol.24 (26), p.2887

2017

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Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1919-1924

2018

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Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents

Anti-cancer agents in medicinal chemistry, 2021-01, Vol.21 (9), p.1127-1140

2021

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Expedition to Phenanthrene Nucleus: A Two‐decade Research on Bench

Asian journal of organic chemistry, 2021-08, Vol.10 (8), p.2105-2136

2021

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Ru(II)-Catalyzed Regioselective C–N Bond Formation on Benzothiazoles Employing Acyl Azide as an Amidating Agent

ACS omega, 2022-01, Vol.7 (1), p.1299-1310

2022

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Contribution of Knoevenagel Condensation Products toward the Development of Anticancer Agents: An Updated Review

ChemMedChem, 2022-04, Vol.17 (8), p.e202100736-n/a

2022

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Niclosamide inhibits epithelial-mesenchymal transition with apoptosis induction in BRAF/ NRAS mutated metastatic melanoma cells

Toxicology in vitro, 2023-06, Vol.89, p.105579-105579, Article 105579

2023

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Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2,4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies

New journal of chemistry, 2018, Vol.42 (19), p.16226-16236

2018

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Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect

European journal of medicinal chemistry, 2020-08, Vol.200, p.112457, Article 112457

2020

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Ru(II)-Catalyzed Regioselective Hydroxymethylation of β‑Carbolines and Isoquinolines via C–H Functionalization: Probing the Mechanism by Online ESI-MS/MS Screening

Journal of organic chemistry, 2019-05, Vol.84 (9), p.5504-5513

2019

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β-Carboline directed regioselective hydroxylation by employing Cu(OAc) and mechanistic investigation by ESI-MS

Organic & biomolecular chemistry, 2020-03, Vol.18 (12), p.237-2311

2020

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Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition

Bioorganic & medicinal chemistry, 2019-08, Vol.27 (15), p.3285-3298

2019

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Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: Synthesis, in silico and cell growth inhibition studies

Bioorganic chemistry, 2021-05, Vol.110, p.104765, Article 104765

2021

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Reliability of Click Chemistry on Drug Discovery: A Personal Account

Chemical record, 2020-04, Vol.20 (4), p.253-272

2020

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Design and Synthesis of DNA‐Interactive β‐Carboline–Oxindole Hybrids as Cytotoxic and Apoptosis‐Inducing Agents

ChemMedChem, 2018-09, Vol.13 (18), p.1909-1922

2018

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Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity

Bioorganic chemistry, 2020-12, Vol.105, p.104357-104357, Article 104357

2020

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Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction

Bioorganic chemistry, 2021-01, Vol.106, p.104481-104481, Article 104481

2021

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Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies

Bioorganic & medicinal chemistry, 2018-05, Vol.26 (8), p.1996-2008

2018

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Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines

RSC advances, 2020-04, Vol.1 (27), p.1611-1619

2020

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Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding

Bioorganic & medicinal chemistry, 2021-08, Vol.43, p.116277-116277, Article 116277

2021

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β-Carboline directed regioselective hydroxylation by employing Cu(OAc) 2 and mechanistic investigation by ESI-MS

Organic & biomolecular chemistry, 2020-03, Vol.18 (12), p.2307-2311

2020

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Synthesis of Combretastatin‐A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization

ChemMedChem, 2019-12, Vol.14 (24), p.2052-2060

2019

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Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors

Bioorganic chemistry, 2019-12, Vol.93, p.103317, Article 103317

2019

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Synthesis of DNA interactive C3-trans-cinnamide linked β-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors

Bioorganic & medicinal chemistry, 2018-09, Vol.26 (17), p.4916-4929

2018

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Exploration of mercaptoacetamide-linked pyrimidine-1,3,4-oxadiazole derivatives as DNA intercalative topo II inhibitors: Cytotoxicity and apoptosis induction

Bioorganic & medicinal chemistry letters, 2022-06, Vol.65, p.128697-128697, Article 128697

2022

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Targeting DNA Minor Groove by Hybrid Molecules as Anticancer Agents

Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents

Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents

Expedition to Phenanthrene Nucleus: A Two‐decade Research on Bench

Ru(II)-Catalyzed Regioselective C–N Bond Formation on Benzothiazoles Employing Acyl Azide as an Amidating Agent

Contribution of Knoevenagel Condensation Products toward the Development of Anticancer Agents: An Updated Review

Niclosamide inhibits epithelial-mesenchymal transition with apoptosis induction in BRAF/ NRAS mutated metastatic melanoma cells

Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2,4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies

Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect

Ru(II)-Catalyzed Regioselective Hydroxymethylation of β‑Carbolines and Isoquinolines via C–H Functionalization: Probing the Mechanism by Online ESI-MS/MS Screening

β-Carboline directed regioselective hydroxylation by employing Cu(OAc) and mechanistic investigation by ESI-MS

Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition

Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: Synthesis, in silico and cell growth inhibition studies

Reliability of Click Chemistry on Drug Discovery: A Personal Account

Design and Synthesis of DNA‐Interactive β‐Carboline–Oxindole Hybrids as Cytotoxic and Apoptosis‐Inducing Agents

Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity

Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction

Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies

Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines

Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding

β-Carboline directed regioselective hydroxylation by employing Cu(OAc) 2 and mechanistic investigation by ESI-MS

Synthesis of Combretastatin‐A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization

Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors

Synthesis of DNA interactive C3-trans-cinnamide linked β-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors

Exploration of mercaptoacetamide-linked pyrimidine-1,3,4-oxadiazole derivatives as DNA intercalative topo II inhibitors: Cytotoxicity and apoptosis induction

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