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Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562

Cancer letters, 2010-03, Vol.289 (1), p.46-52

2010

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Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

Cancer research (Chicago, Ill.), 2009-07, Vol.69 (14), p.5876-5884

2009

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Electrocardiographic Characterization of the QTc Interval in Patients with Advanced Solid Tumors: Pharmacokinetic- Pharmacodynamic Evaluation of Sunitinib

Clinical cancer research, 2009-11, Vol.15 (22), p.7045-7052

2009

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1336 Cancer vaccine co-targeting PRAME and PD-L1 exerts significant tumor growth inhibition in syngeneic mouse hepatocellular carcinoma models

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1487-A1487

2023

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Cognitive testing in early-phase clinical trials: Development of a rapid computerized test battery and application in a simulated Phase I study

Contemporary clinical trials, 2007-07, Vol.28 (4), p.391-400

2007

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Abstract 4106: A novel synthetic long peptide vaccine composition targeting multiple PD-L1 T-cell epitopes exhibits anti-tumor efficacy in a syngeneic mouse colorectal cancer model

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.4106-4106

2024

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Abstract 4111: Multi-peptide cancer vaccines targeting KRAS induce significant anti-tumor efficacy

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.4111-4111

2024

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Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration

Cancer letters, 2010-08, Vol.294 (1), p.118-124

2010

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Zolpidem Mucoadhesive Formulations for Intranasal Delivery: Characterization, In Vitro Permeability, Pharmacokinetics, and Nasal Ciliotoxicity in Rats

Journal of pharmaceutical sciences, 2016-09, Vol.105 (9), p.2840-2847

2016

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Abstract 3525: Towards the efficient design of shared neoantigen peptide cancer vaccines using artificial intelligence

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.3525-3525

2024

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The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer

International journal of cancer, 2013-06, Vol.132 (12), p.2730-2737

2013

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Modulation of 11β-Hydroxysteroid Dehydrogenase (11βHSD) Activity Biomarkers and Pharmacokinetics of PF-00915275, a Selective 11βHSD1 Inhibitor

The journal of clinical endocrinology and metabolism, 2008-02, Vol.93 (2), p.550-556

2008

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Pharmacokinetics of sunitinib malate in subjects with hepatic impairment

Cancer chemotherapy and pharmacology, 2010-09, Vol.66 (4), p.699-707

2010

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Pharmacokinetics of a Novel Zolpidem Nasal Spray for Rapid Management of Insomnia: First Trial in Humans

Journal of clinical sleep medicine, 2016-11, Vol.12 (11), p.1453-1459

2016

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Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

British journal of pharmacology, 2010-06, Vol.160 (4), p.998-1007

2010

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Pharmacokinetics and Safety of Sunitinib Malate in Subjects With Impaired Renal Function

Journal of clinical pharmacology, 2010-04, Vol.50 (4), p.472-481

2010

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Effect of axitinib on the QT interval in healthy volunteers

Cancer chemotherapy and pharmacology, 2015-03, Vol.75 (3), p.619-628

2015

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Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers

Cancer chemotherapy and pharmacology, 2012-07, Vol.70 (1), p.103-112

2012

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Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics

Investigational new drugs, 2011-12, Vol.29 (6), p.1370-1380

2011

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The triterpenoid Cucurbitacin B augments the anti-proliferative activity of chemotherapy in human breast cancer

International journal of cancer, 2012-12, Vol.132 (12), p.2730-2737

2012

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Abstract 5396: Synergistic effect of cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5396-5396

2010

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Abstract 5383: Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.5383-5383

2010

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Modulation of 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity biomarkers and pharmacokinetics of PF-00915275, a selective 11betaHSD1 inhibitor

The journal of clinical endocrinology and metabolism, 2008-02, Vol.93 (2), p.550

2008

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Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD

The journal of clinical endocrinology and metabolism, 2018-07, Vol.103 (7), p.2698-2706

2018

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High surface laser-induced damage threshold of SrB4O7 single crystals under 266-nm (DUV) laser irradiation

Optics express, 2020-09, Vol.28 (20), p.29239-29244

2020

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Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562

Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

Electrocardiographic Characterization of the QTc Interval in Patients with Advanced Solid Tumors: Pharmacokinetic- Pharmacodynamic Evaluation of Sunitinib

1336 Cancer vaccine co-targeting PRAME and PD-L1 exerts significant tumor growth inhibition in syngeneic mouse hepatocellular carcinoma models

Cognitive testing in early-phase clinical trials: Development of a rapid computerized test battery and application in a simulated Phase I study

Abstract 4106: A novel synthetic long peptide vaccine composition targeting multiple PD-L1 T-cell epitopes exhibits anti-tumor efficacy in a syngeneic mouse colorectal cancer model

Abstract 4111: Multi-peptide cancer vaccines targeting KRAS induce significant anti-tumor efficacy

Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration

Zolpidem Mucoadhesive Formulations for Intranasal Delivery: Characterization, In Vitro Permeability, Pharmacokinetics, and Nasal Ciliotoxicity in Rats

Abstract 3525: Towards the efficient design of shared neoantigen peptide cancer vaccines using artificial intelligence

The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer

Modulation of 11β-Hydroxysteroid Dehydrogenase (11βHSD) Activity Biomarkers and Pharmacokinetics of PF-00915275, a Selective 11βHSD1 Inhibitor

Pharmacokinetics of sunitinib malate in subjects with hepatic impairment

Pharmacokinetics of a Novel Zolpidem Nasal Spray for Rapid Management of Insomnia: First Trial in Humans

Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

Pharmacokinetics and Safety of Sunitinib Malate in Subjects With Impaired Renal Function

Effect of axitinib on the QT interval in healthy volunteers

Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers

Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics

The triterpenoid Cucurbitacin B augments the anti-proliferative activity of chemotherapy in human breast cancer

Abstract 5396: Synergistic effect of cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma

Abstract 5383: Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

Modulation of 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity biomarkers and pharmacokinetics of PF-00915275, a selective 11betaHSD1 inhibitor

Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD

High surface laser-induced damage threshold of SrB4O7 single crystals under 266-nm (DUV) laser irradiation

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