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Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Cell, 2013-12, Vol.155 (6), p.1422-1434

2013

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Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets

Cell, 2017-01, Vol.168 (1-2), p.159-171.e14

2017

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A bright future: optogenetics to dissect the spatiotemporal control of cell behavior

Current opinion in chemical biology, 2019-02, Vol.48, p.106-113

2019

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Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

Cell, 2018-11, Vol.175 (6), p.1467-1480.e13

2018

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Optogenetic regulation of engineered cellular metabolism for microbial chemical production

Nature (London), 2018-03, Vol.555 (7698), p.683-687

2018

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Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control

Molecular cell, 2017-09, Vol.67 (5), p.757-769.e5

2017

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Light-based control of metabolic flux through assembly of synthetic organelles

Nature chemical biology, 2019-06, Vol.15 (6), p.589-597

2019

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The Spatiotemporal Limits of Developmental Erk Signaling

Developmental cell, 2017-01, Vol.40 (2), p.185-192

2017

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Light-switchable transcription factors obtained by direct screening in mammalian cells

Nature communications, 2023-06, Vol.14 (1), p.3185-16, Article 3185

2023

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Light-based feedback for controlling intracellular signaling dynamics

Nature methods, 2011-10, Vol.8 (10), p.837-839

2011

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Optogenetic control of protein binding using light-switchable nanobodies

Nature communications, 2020-08, Vol.11 (1), p.4044-4044, Article 4044

2020

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Four Key Steps Control Glycolytic Flux in Mammalian Cells

Cell systems, 2018-07, Vol.7 (1), p.49-62.e8

2018

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Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli

Cell systems, 2018-06, Vol.6 (6), p.655-663.e5

2018

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Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

Nature communications, 2024-08, Vol.15 (1), p.6717-13, Article 6717

2024

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The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

Nature methods, 2011-01, Vol.8 (1), p.35-38

2011

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Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold

Nature communications, 2020-08, Vol.11 (1), p.4045-4045, Article 4045

2020

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Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation

Cell reports (Cambridge), 2022-03, Vol.38 (12), p.110543-110543, Article 110543

2022

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Optimizing photoswitchable MEK

Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (51), p.25756-25763

2019

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Stochastic Gene Expression in a Lentiviral Positive-Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic Diversity

Cell, 2005-07, Vol.122 (2), p.169-182

2005

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A self-exciting point process to study multicellular spatial signaling patterns

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (32), p.1

2021

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Light-guided embryogenesis: Using optogenetics to probe and replace developmental signaling patterns

Biophysical journal, 2023-02, Vol.122 (3), p.18a-18a

Toettcher, Jared E.

2023

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Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

Cell, 2019-01, Vol.176 (1-2), p.407-407

2019

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Signaling Dynamics Control Cell Fate in the Early Drosophila Embryo

Developmental cell, 2019-02, Vol.48 (3), p.361-370.e3

2019

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A size-invariant bud-duration timer enables robustness in yeast cell size control

PloS one, 2018-12, Vol.13 (12), p.e0209301-e0209301

2018

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Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration

PLoS biology, 2016-02, Vol.14 (2), p.e1002381-e1002381

2016

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Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets

A bright future: optogenetics to dissect the spatiotemporal control of cell behavior

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

Optogenetic regulation of engineered cellular metabolism for microbial chemical production

Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control

Light-based control of metabolic flux through assembly of synthetic organelles

The Spatiotemporal Limits of Developmental Erk Signaling

Light-switchable transcription factors obtained by direct screening in mammalian cells

Light-based feedback for controlling intracellular signaling dynamics

Optogenetic control of protein binding using light-switchable nanobodies

Four Key Steps Control Glycolytic Flux in Mammalian Cells

Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli

Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold

Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation

Optimizing photoswitchable MEK

Stochastic Gene Expression in a Lentiviral Positive-Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic Diversity

A self-exciting point process to study multicellular spatial signaling patterns

Light-guided embryogenesis: Using optogenetics to probe and replace developmental signaling patterns

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

Signaling Dynamics Control Cell Fate in the Early Drosophila Embryo

A size-invariant bud-duration timer enables robustness in yeast cell size control

Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration

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