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Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

Nature reviews. Drug discovery, 2003-07, Vol.2 (7), p.517-526

Tobert, Jonathan A

2003

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Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S)

Circulation (New York, N.Y.), 1998-04, Vol.97 (15), p.1453-1460

1998

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Effect of Simvastatin on Ischemic Signs and Symptoms in the Scandinavian Simvastatin Survival Study (4S)

The American journal of cardiology, 1998-02, Vol.81 (3), p.333-335

1998

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Simvastatin: a review

Expert opinion on pharmacotherapy, 2004-12, Vol.5 (12), p.2583-2596

2004

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Effects of high doses of simvastatin and atorvastatin on high-density lipoprotein cholesterol and apolipoprotein A-I

The American journal of cardiology, 1999-05, Vol.83 (10), p.1476-1477

1999

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Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin

The American journal of cardiology, 1999-10, Vol.84 (7), p.811-815

1999

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Efficacy and long-term adverse effect pattern of lovastatin

The American journal of cardiology, 1988-11, Vol.62 (15), p.J28-J34

Tobert, Jonathan A.

1988

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The Efficacy and Six-Week Tolerability of Simvastatin 80 and 160 mg/Day

The American journal of cardiology, 1997-01, Vol.79 (1), p.38-42

1997

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efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia

The New England journal of medicine, 1993-04, Vol.328 (17), p.1213-1219

1993

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A review of clinical trials comparing HMG-CoA reductase inhibitors

Clinical therapeutics, 1994-05, Vol.16 (3), p.366-385

1994

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Benefits and risks of HMG-CoA reductase inhibitors in the prevention of coronary heart disease: a reappraisal

Drug safety, 1996-01, Vol.14 (1), p.11-24

1996

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Therapeutic Response to Lovastatin (Mevinolin) in Nonfamilial Hypercholesterolemia: A Multicenter Study

JAMA : the journal of the American Medical Association, 1986-11, Vol.256 (20), p.2829

1986

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Effects of simvastatin on the lipid profile and attainment of low-density lipoprotein cholesterol goals when added to thiazolidinedione therapy in patients with type 2 diabetes mellitus: A multicenter, randomized, double-blind, placebo-controlled trial

Clinical therapeutics, 2004, Vol.26 (3), p.379-389

2004

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New developments in lipid-lowering therapy: the role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase

Circulation (New York, N.Y.), 1987-09, Vol.76 (3), p.534-538

TOBERT, J. A

1987

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A Multicenter Comparison of Lovastatin and Cholestyramine Therapy for Severe Primary Hypercholesterolemia

JAMA : the journal of the American Medical Association, 1988-07, Vol.260 (3), p.359

1988

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A multicenter comparison of lovastatin and probucol for treatment of severe primary hypercholesterolemia

The American journal of cardiology, 1990-09, Vol.66 (8), p.B22-B30

The Lovastatin Study Group IV

1990

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Lovastatin (mevinolin) in the treatment of heterozygous familial hypercholesterolemia. A multicenter study

Annals of internal medicine, 1987-11, Vol.107 (5), p.609

1987

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Statin therapy and CHD

The Lancet (British edition), 1996-01, Vol.347 (8994), p.128-128

Tobert, JonathanA

1996

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Lovastatin-associated sleep and mood disturbances

The American journal of medicine, 1995-07, Vol.99 (1), p.108-109

Tobert, Jonathan A.

1995

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HMG-CoA reductase inhibitors, gemfibrozil, and myopathy

The American journal of cardiology, 1995-04, Vol.75 (12), p.862-862

Tobert, Jonathan A.

1995

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Carcinogenicity of lipid-lowering drugs

JAMA : the journal of the American Medical Association, 1996-05, Vol.275 (19), p.1480

Tobert, J A

1996

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Lovastatin and myopathy

The American journal of medicine, 1994-03, Vol.96 (3), p.300-301

Tobert, Jonathan A.

1994

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Calcium channel blocker-simvastatin interaction

Clinical pharmacology and therapeutics, 1999-05, Vol.65 (5), p.583

1999

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Clinical experience with lovastatin

The American journal of cardiology, 1990-03, Vol.65 (12), p.23-26

1990

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Addressing a Treatment Gap: Rationale for Increasing the Starting Dose of Simvastatin in Hypercholesterolaemic Patients

Clinical drug investigation, 2002, Vol.22 (5), p.291-301

2002

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Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S)

Effect of Simvastatin on Ischemic Signs and Symptoms in the Scandinavian Simvastatin Survival Study (4S)

Simvastatin: a review

Effects of high doses of simvastatin and atorvastatin on high-density lipoprotein cholesterol and apolipoprotein A-I

Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin

Efficacy and long-term adverse effect pattern of lovastatin

The Efficacy and Six-Week Tolerability of Simvastatin 80 and 160 mg/Day

efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia

A review of clinical trials comparing HMG-CoA reductase inhibitors

Benefits and risks of HMG-CoA reductase inhibitors in the prevention of coronary heart disease: a reappraisal

Therapeutic Response to Lovastatin (Mevinolin) in Nonfamilial Hypercholesterolemia: A Multicenter Study

Effects of simvastatin on the lipid profile and attainment of low-density lipoprotein cholesterol goals when added to thiazolidinedione therapy in patients with type 2 diabetes mellitus: A multicenter, randomized, double-blind, placebo-controlled trial

New developments in lipid-lowering therapy: the role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase

A Multicenter Comparison of Lovastatin and Cholestyramine Therapy for Severe Primary Hypercholesterolemia

A multicenter comparison of lovastatin and probucol for treatment of severe primary hypercholesterolemia

Lovastatin (mevinolin) in the treatment of heterozygous familial hypercholesterolemia. A multicenter study

Statin therapy and CHD

Lovastatin-associated sleep and mood disturbances

HMG-CoA reductase inhibitors, gemfibrozil, and myopathy

Carcinogenicity of lipid-lowering drugs

Lovastatin and myopathy

Calcium channel blocker-simvastatin interaction

Clinical experience with lovastatin

Addressing a Treatment Gap: Rationale for Increasing the Starting Dose of Simvastatin in Hypercholesterolaemic Patients

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