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Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase of Trypanosoma brucei

The Journal of biological chemistry, 2013-09, Vol.288 (38), p.27456-27468

2013

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Polyglutamine-Expanded Ataxin-7 Inhibits STAGA Histone Acetyltransferase Activity to Produce Retinal Degeneration

Proceedings of the National Academy of Sciences - PNAS, 2005-06, Vol.102 (24), p.8472-8477

2005

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Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo

Molecular and Cellular Biology, 2001-10, Vol.21 (20), p.6782-6795

2001

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Intravenous delivery of a chemically modified sulfamidase efficiently reduces heparan sulfate storage and brain pathology in mucopolysaccharidosis IIIA mice

Molecular genetics and metabolism reports, 2019-12, Vol.21, p.100510, Article 100510

2019

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DMSO-related effects in protein characterization

Journal of biomolecular screening, 2006-03, Vol.11 (2), p.131-137

2006

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Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome

iScience, 2021-03, Vol.24 (3), p.102154-102154, Article 102154

2021

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Determination of Dissociation Constants for Protein−Ligand Complexes by Electrospray Ionization Mass Spectrometry

Analytical chemistry (Washington), 2004-08, Vol.76 (15), p.4325-4331

2004

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Requirement of Ca2+ and CaMKII for Stat1 Ser-727 Phosphorylation in Response to IFN-γ

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (9), p.5971-5976

2002

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SYT Associates with Human SNF/SWI Complexes and the C-terminal Region of Its Fusion Partner SSX1 Targets Histones

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.5498-5505

2002

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Human TATA-Binding Protein-Related Factor-2 (hTRF2) Stably Associates with hTFIIA in HeLa Cells

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (24), p.13720-13725

1999

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Improved identification of host cell proteins in a protein biopharmaceutical by LC–MS/MS using the ProteoMiner™ Enrichment Kit

Journal of pharmaceutical and biomedical analysis, 2020-06, Vol.185, p.113256-113256, Article 113256

2020

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Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione

The Journal of pharmacology and experimental therapeutics, 2004-05, Vol.309 (2), p.711

2004

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Robust LC–MS/MS methods for analysis of heparan sulfate levels in CSF and brain for application in studies of MPS IIIA

Bioanalysis, 2019-08, Vol.11 (15), p.1389-1403

2019

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A molecular model of Alzheimer amyloid beta-peptide fibril formation

The Journal of biological chemistry, 1999-04, Vol.274 (18), p.12619-12625

1999

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1- and 3-hydroxylations, in addition to 4-hydroxylation, of debrisoquine are catalyzed by cytochrome P450 2D6 in humans

Drug metabolism and disposition, 1998-11, Vol.26 (11), p.1096

1998

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A Microsomal GTPase Is Required for Glycopeptide Export from the Mammalian Endoplasmic Reticulum

The Journal of biological chemistry, 2000-10, Vol.275 (43), p.33222-33230

2000

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Development of a two-dimensional liquid chromatography system for isolation of drug metabolites

Journal of pharmaceutical and biomedical analysis, 2010-02, Vol.51 (3), p.649-657

2010

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Folding into a β-Hairpin Can Prevent Amyloid Fibril Formation

Biochemistry (Easton), 2004-04, Vol.43 (16), p.4655-4661

2004

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Assembling amyloid fibrils from designed structures containing a significant amyloid beta-peptide fragment

Biochemical journal, 2002-08, Vol.366 (Pt 1), p.343-351

2002

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Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B)

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (4), p.891-895

2004

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Protein Mass Spectrometry in the Drug Discovery Process

Tjernberg, Agneta

2005

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Matrix-assisted laser desorption/ionization mass spectrometry of proteins extracted directly from sodium dodecyl sulphate-polyacrylamide gels

Rapid communications in mass spectrometry, 1997-01, Vol.11 (17), p.1867-1873

1997

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Requirement of Ca 2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (9), p.5971-5976

2002

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Characterization of periplasmic Escherichia coli protein expression at high cell densities

Electrophoresis, 1999-04, Vol.20 (4-5), p.790-797

1999

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SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones

The Journal of biological chemistry, 2002-04, Vol.277 (16), p.14350-14350

2002

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Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase of Trypanosoma brucei

Polyglutamine-Expanded Ataxin-7 Inhibits STAGA Histone Acetyltransferase Activity to Produce Retinal Degeneration

Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo

Intravenous delivery of a chemically modified sulfamidase efficiently reduces heparan sulfate storage and brain pathology in mucopolysaccharidosis IIIA mice

DMSO-related effects in protein characterization

Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome

Determination of Dissociation Constants for Protein−Ligand Complexes by Electrospray Ionization Mass Spectrometry

Requirement of Ca2+ and CaMKII for Stat1 Ser-727 Phosphorylation in Response to IFN-γ

SYT Associates with Human SNF/SWI Complexes and the C-terminal Region of Its Fusion Partner SSX1 Targets Histones

Human TATA-Binding Protein-Related Factor-2 (hTRF2) Stably Associates with hTFIIA in HeLa Cells

Improved identification of host cell proteins in a protein biopharmaceutical by LC–MS/MS using the ProteoMiner™ Enrichment Kit

Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione

Robust LC–MS/MS methods for analysis of heparan sulfate levels in CSF and brain for application in studies of MPS IIIA

A molecular model of Alzheimer amyloid beta-peptide fibril formation

1- and 3-hydroxylations, in addition to 4-hydroxylation, of debrisoquine are catalyzed by cytochrome P450 2D6 in humans

A Microsomal GTPase Is Required for Glycopeptide Export from the Mammalian Endoplasmic Reticulum

Development of a two-dimensional liquid chromatography system for isolation of drug metabolites

Folding into a β-Hairpin Can Prevent Amyloid Fibril Formation

Assembling amyloid fibrils from designed structures containing a significant amyloid beta-peptide fragment

Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B)

Protein Mass Spectrometry in the Drug Discovery Process

Matrix-assisted laser desorption/ionization mass spectrometry of proteins extracted directly from sodium dodecyl sulphate-polyacrylamide gels

Requirement of Ca 2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ

Characterization of periplasmic Escherichia coli protein expression at high cell densities

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones

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